Systematic engineering of 3D pluripotent stem cell niches to guide blood development

Biomaterials

Volumn 33, Issue 5, 2012, Pages 1271-1280

  Purpura, Kelly A ^a,b   Bratt Leal, Andrés M ^e   Hammersmith, Katy A ^e   McDevitt, Todd C ^e   Zandstra, Peter W ^a,b,c,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d HEART AND STROKE FOUNDATION OF CANADA   (Canada)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Blood progenitor cell; Gelatin; Heparin; Microparticles; Stem cells

Indexed keywords

AGGREGATE SIZE; BLOOD PROGENITORS; BONE MORPHOGENETIC PROTEIN-4; CELL THERAPY; DELIVERY METHODS; DIFFERENTIATION RESPONSE; E-CADHERINS; EMBRYONIC STEM CELLS; ENDOGENOUS SIGNALING; ENVIRONMENTAL SIGNALS; FUNCTIONAL CELLS; GELATIN; GROWTH FACTOR; HEMATOPOIETIC PROGENITOR CELLS; HEPARIN; IN-VIVO; LOCALIZED DELIVERY; LOW OXYGEN; MICRO-PARTICLES; MICROENVIRONMENTS; PHENOTYPIC MARKERS; PLURIPOTENT STEM CELLS; SYSTEMATIC ENGINEERING; THROMBOPOIETIN;

BLOOD; CELL GROWTH; CHLOROFLUOROCARBONS; CYTOLOGY;

STEM CELLS;

BONE MORPHOGENETIC PROTEIN 4; BRACHYURY; GREEN FLUORESCENT PROTEIN; OXYGEN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; THROMBOPOIETIN; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN RECEPTOR 2;

ARTICLE; BLOOD CELL; COLONY FORMING CELL; EMBRYONIC STEM CELL; MESODERM; MICROPARTICLE ENZYME IMMUNOASSAY; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

BIOMEDICAL ENGINEERING; BODY PATTERNING; BONE MORPHOGENETIC PROTEIN 4; CELL AGGREGATION; CELL-DERIVED MICROPARTICLES; GELATIN; HEMATOPOIETIC STEM CELLS; HUMANS; MESODERM; OXYGEN; PHENOTYPE; PLURIPOTENT STEM CELLS; STEM CELL NICHE;

EID: 83355169558     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.10.051     Document Type: Article

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