메뉴 건너뛰기




Volumn 7, Issue 10, 2012, Pages

Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF GROWTH 4 PROTEIN; TRANSCRIPTION FACTOR RELA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84867137097     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046823     Document Type: Article
Times cited : (43)

References (56)
  • 1
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S, (2008) Shared principles in NF-kappaB signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 2
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • Vallabhapurapu S, Karin M, (2009) Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27: 693-733.
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 3
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-κB as the matchmaker
    • Ben-Neriah Y, Karin M, (2011) Inflammation meets cancer, with NF-κB as the matchmaker. Nat Immunol 12: 715-723.
    • (2011) Nat Immunol , vol.12 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 4
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M, (2010) Immunity, inflammation, and cancer. Cell 140: 883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 6
    • 3042716638 scopus 로고    scopus 로고
    • NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis
    • Biswas DK, Shi Q, Baily S, Strickland I, Ghosh S, et al. (2004) NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc Natl Acad Sci U S A 101: 10137-10142.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10137-10142
    • Biswas, D.K.1    Shi, Q.2    Baily, S.3    Strickland, I.4    Ghosh, S.5
  • 7
    • 2342641439 scopus 로고    scopus 로고
    • Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway
    • Makino K, Day CP, Wang SC, Li YM, Hung MC, (2004) Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway. Oncogene 23: 3883-3887.
    • (2004) Oncogene , vol.23 , pp. 3883-3887
    • Makino, K.1    Day, C.P.2    Wang, S.C.3    Li, Y.M.4    Hung, M.C.5
  • 8
    • 33750495811 scopus 로고    scopus 로고
    • Linkage between EGFR family receptors and nuclear factor kappaB (NF-kappaB) signaling in breast cancer
    • Biswas DK, Iglehart JD, (2006) Linkage between EGFR family receptors and nuclear factor kappaB (NF-kappaB) signaling in breast cancer. J Cell Physiol 209: 645-652.
    • (2006) J Cell Physiol , vol.209 , pp. 645-652
    • Biswas, D.K.1    Iglehart, J.D.2
  • 9
    • 77649190700 scopus 로고    scopus 로고
    • Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha
    • Merkhofer EC, Cogswell P, Baldwin AS, (2010) Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene 29: 1238-1248.
    • (2010) Oncogene , vol.29 , pp. 1238-1248
    • Merkhofer, E.C.1    Cogswell, P.2    Baldwin, A.S.3
  • 10
    • 35648970074 scopus 로고    scopus 로고
    • IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
    • Cao Y, Luo JL, Karin M, (2007) IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. Proc Natl Acad Sci U S A 104: 15852-15857.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15852-15857
    • Cao, Y.1    Luo, J.L.2    Karin, M.3
  • 11
    • 65649107679 scopus 로고    scopus 로고
    • Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo
    • Liu M, Ju X, Willmarth NE, Casimiro MC, Ojeifo J, et al. (2009) Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol 174: 1910-1920.
    • (2009) Am J Pathol , vol.174 , pp. 1910-1920
    • Liu, M.1    Ju, X.2    Willmarth, N.E.3    Casimiro, M.C.4    Ojeifo, J.5
  • 12
    • 78650369893 scopus 로고    scopus 로고
    • The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion
    • Liu M, Sakamaki T, Casimiro MC, Willmarth NE, Quong AA, et al. (2010) The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion. Cancer Res 70: 10464-10473.
    • (2010) Cancer Res , vol.70 , pp. 10464-10473
    • Liu, M.1    Sakamaki, T.2    Casimiro, M.C.3    Willmarth, N.E.4    Quong, A.A.5
  • 14
    • 34247242607 scopus 로고    scopus 로고
    • Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
    • Zhou Y, Yau C, Gray JW, Chew K, Dairkee SH, et al. (2007) Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. BMC Cancer 7: 1-15.
    • (2007) BMC Cancer , vol.7 , pp. 1-15
    • Zhou, Y.1    Yau, C.2    Gray, J.W.3    Chew, K.4    Dairkee, S.H.5
  • 15
    • 71549124954 scopus 로고    scopus 로고
    • Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer
    • Frasor J, Weaver A, Pradhan M, Dai Y, Miller LD, et al. (2009) Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer. Cancer Res 69: 8918-8925.
    • (2009) Cancer Res , vol.69 , pp. 8918-8925
    • Frasor, J.1    Weaver, A.2    Pradhan, M.3    Dai, Y.4    Miller, L.D.5
  • 16
    • 77957764181 scopus 로고    scopus 로고
    • Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements
    • Pradhan M, Bembinster LA, Baumgarten SC, Frasor J, (2010) Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements. J Biol Chem 285: 31100-31106.
    • (2010) J Biol Chem , vol.285 , pp. 31100-31106
    • Pradhan, M.1    Bembinster, L.A.2    Baumgarten, S.C.3    Frasor, J.4
  • 18
    • 67349253400 scopus 로고    scopus 로고
    • Inhibitor of growth 4 induces apoptosis in human lung adenocarcinoma cell line A549 via Bcl-2 family proteins and mitochondria apoptosis pathway
    • Li X, Zhang Q, Cai L, Wang Y, Wang Q, et al. (2009) Inhibitor of growth 4 induces apoptosis in human lung adenocarcinoma cell line A549 via Bcl-2 family proteins and mitochondria apoptosis pathway. J Cancer Res Clin Oncol 135: 829-835.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 829-835
    • Li, X.1    Zhang, Q.2    Cai, L.3    Wang, Y.4    Wang, Q.5
  • 19
    • 34047273596 scopus 로고    scopus 로고
    • Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1
    • Shen JC, Unoki M, Ythier D, Duperray A, Varticovski L, et al. (2007) Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1. Cancer Res 67: 2552-2558.
    • (2007) Cancer Res , vol.67 , pp. 2552-2558
    • Shen, J.C.1    Unoki, M.2    Ythier, D.3    Duperray, A.4    Varticovski, L.5
  • 20
    • 1642586297 scopus 로고    scopus 로고
    • The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
    • Garkavtsev I, Kozin SV, Chernova O, Xu L, Winkler F, et al. (2004) The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature 428: 328-332.
    • (2004) Nature , vol.428 , pp. 328-332
    • Garkavtsev, I.1    Kozin, S.V.2    Chernova, O.3    Xu, L.4    Winkler, F.5
  • 21
    • 39649104151 scopus 로고    scopus 로고
    • The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis
    • Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, et al. (2007) The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis. Blood 110: 4464-4475.
    • (2007) Blood , vol.110 , pp. 4464-4475
    • Colla, S.1    Tagliaferri, S.2    Morandi, F.3    Lunghi, P.4    Donofrio, G.5
  • 22
    • 78650319117 scopus 로고    scopus 로고
    • Cell cycle regulator ING4 is a suppressor of melanoma angiogenesis that is regulated by the metastasis suppressor BRMS1
    • Li J, Li G, (2010) Cell cycle regulator ING4 is a suppressor of melanoma angiogenesis that is regulated by the metastasis suppressor BRMS1. Cancer Res 70: 10445-10453.
    • (2010) Cancer Res , vol.70 , pp. 10445-10453
    • Li, J.1    Li, G.2
  • 23
    • 9244239717 scopus 로고    scopus 로고
    • A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer
    • Kim S, Chin K, Gray JW, Bishop JM, (2004) A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer. Proc Natl Acad Sci U S A 101: 16251-16256.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16251-16256
    • Kim, S.1    Chin, K.2    Gray, J.W.3    Bishop, J.M.4
  • 24
    • 19644376763 scopus 로고    scopus 로고
    • The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF)
    • Ozer A, Wu LC, Bruick RK, (2005) The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF). Proc Natl Acad Sci U S A 102: 7481-7486.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7481-7486
    • Ozer, A.1    Wu, L.C.2    Bruick, R.K.3
  • 25
    • 55449102824 scopus 로고    scopus 로고
    • The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes
    • Nozell S, Laver T, Moseley D, Nowoslawski L, De Vos M, et al. (2008) The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes. Mol Cell Biol 28: 6632-6645.
    • (2008) Mol Cell Biol , vol.28 , pp. 6632-6645
    • Nozell, S.1    Laver, T.2    Moseley, D.3    Nowoslawski, L.4    de Vos, M.5
  • 26
    • 79959356720 scopus 로고    scopus 로고
    • Deletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer
    • Tapia C, Zlobec I, Schneider S, Kilic E, Güth U, et al. (2011) Deletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer. Hum Pathol 42: 983-990.
    • (2011) Hum Pathol , vol.42 , pp. 983-990
    • Tapia, C.1    Zlobec, I.2    Schneider, S.3    Kilic, E.4    Güth, U.5
  • 27
    • 23844441255 scopus 로고    scopus 로고
    • Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas
    • Gunduz M, Nagatsuka H, Demircan K, Gunduz E, Cengiz B, et al. (2005) Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas. Gene 356: 109-117.
    • (2005) Gene , vol.356 , pp. 109-117
    • Gunduz, M.1    Nagatsuka, H.2    Demircan, K.3    Gunduz, E.4    Cengiz, B.5
  • 28
    • 49349105425 scopus 로고    scopus 로고
    • Role of ING4 in human melanoma cell migration, invasion and patient survival
    • Li J, Martinka M, Li G, (2008) Role of ING4 in human melanoma cell migration, invasion and patient survival. Carcinogenesis 29: 1373-1379.
    • (2008) Carcinogenesis , vol.29 , pp. 1373-1379
    • Li, J.1    Martinka, M.2    Li, G.3
  • 29
    • 60549094969 scopus 로고    scopus 로고
    • Decreased expression of inhibitor of growth 4 correlated with poor prognosis of hepatocellular carcinoma
    • Fang F, Luo LB, Tao YM, Wu F, Yang LY, (2009) Decreased expression of inhibitor of growth 4 correlated with poor prognosis of hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev 18: 409-416.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 409-416
    • Fang, F.1    Luo, L.B.2    Tao, Y.M.3    Wu, F.4    Yang, L.Y.5
  • 30
    • 68849123129 scopus 로고    scopus 로고
    • Reduced expression and novel splice variants of ING4 in human gastric adenocarcinoma
    • Li M, Jin Y, Sun WJ, Yu Y, Bai J, et al. (2009) Reduced expression and novel splice variants of ING4 in human gastric adenocarcinoma. J Pathol 219: 87-95.
    • (2009) J Pathol , vol.219 , pp. 87-95
    • Li, M.1    Jin, Y.2    Sun, W.J.3    Yu, Y.4    Bai, J.5
  • 31
    • 80052704802 scopus 로고    scopus 로고
    • Downregulated Expression of Inhibitor of Growth 4 (ING4) in Advanced Colorectal Cancers: A Non-Randomized Experimental Study
    • You Q, Wang XS, Fu SB, Jin XM, (2011) Downregulated Expression of Inhibitor of Growth 4 (ING4) in Advanced Colorectal Cancers: A Non-Randomized Experimental Study. Pathol Oncol Res 17: 473-477.
    • (2011) Pathol Oncol Res , vol.17 , pp. 473-477
    • You, Q.1    Wang, X.S.2    Fu, S.B.3    Jin, X.M.4
  • 32
    • 77955834791 scopus 로고    scopus 로고
    • Down-regulation of ING4 is associated with initiation and progression of lung cancer
    • Wang QS, Li M, Zhang LY, Jin Y, Tong DD, et al. (2010) Down-regulation of ING4 is associated with initiation and progression of lung cancer. Histopathology 57: 271-281.
    • (2010) Histopathology , vol.57 , pp. 271-281
    • Wang, Q.S.1    Li, M.2    Zhang, L.Y.3    Jin, Y.4    Tong, D.D.5
  • 33
    • 77954914085 scopus 로고    scopus 로고
    • Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity
    • Coles AH, Gannon H, Cerny A, Kurt-Jones E, Jones SN, (2010) Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity. Proc Natl Acad Sci U S A 107: 11423-11428.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11423-11428
    • Coles, A.H.1    Gannon, H.2    Cerny, A.3    Kurt-Jones, E.4    Jones, S.N.5
  • 34
    • 77953766708 scopus 로고    scopus 로고
    • A Dominant Mutant Allele of the ING4 Tumor Suppressor Found in Human Cancer Cells Exacerbates MYC-Initiated Mouse Mammary Tumorigenesis
    • Kim S, Welm AL, Bishop JM, (2010) A Dominant Mutant Allele of the ING4 Tumor Suppressor Found in Human Cancer Cells Exacerbates MYC-Initiated Mouse Mammary Tumorigenesis. Cancer Res 70: 5155-5162.
    • (2010) Cancer Res , vol.70 , pp. 5155-5162
    • Kim, S.1    Welm, A.L.2    Bishop, J.M.3
  • 35
    • 33645224637 scopus 로고    scopus 로고
    • Grow-ING, Age-ING and Die-ING: ING proteins link cancer, senescence and apoptosis
    • Russell M, Berardi P, Gong W, Riabowol K, (2006) Grow-ING, Age-ING and Die-ING: ING proteins link cancer, senescence and apoptosis. Exp Cell Res 312: 951-961.
    • (2006) Exp Cell Res , vol.312 , pp. 951-961
    • Russell, M.1    Berardi, P.2    Gong, W.3    Riabowol, K.4
  • 36
    • 0028861418 scopus 로고
    • The PHD finger: implications for chromatin-mediated transcriptional regulation
    • Aasland R, Gibson TJ, Stewart AF, (1995) The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci 20: 56-59.
    • (1995) Trends Biochem Sci , vol.20 , pp. 56-59
    • Aasland, R.1    Gibson, T.J.2    Stewart, A.F.3
  • 38
    • 58649102691 scopus 로고    scopus 로고
    • ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
    • Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, et al. (2009) ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Mol Cell 33: 248-256.
    • (2009) Mol Cell , vol.33 , pp. 248-256
    • Hung, T.1    Binda, O.2    Champagne, K.S.3    Kuo, A.J.4    Johnson, K.5
  • 39
    • 29544444195 scopus 로고    scopus 로고
    • ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation
    • Doyon Y, Cayrou C, Ullah M, Landry AJ, Côté V, et al. (2006) ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell 21: 51-64.
    • (2006) Mol Cell , vol.21 , pp. 51-64
    • Doyon, Y.1    Cayrou, C.2    Ullah, M.3    Landry, A.J.4    Côté, V.5
  • 40
    • 58649113419 scopus 로고    scopus 로고
    • HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail
    • Saksouk N, Avvakumov N, Champagne KS, Hung T, Doyon Y, et al. (2009) HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell 33: 257-265.
    • (2009) Mol Cell , vol.33 , pp. 257-265
    • Saksouk, N.1    Avvakumov, N.2    Champagne, K.S.3    Hung, T.4    Doyon, Y.5
  • 41
    • 0032774583 scopus 로고    scopus 로고
    • Production and characterization of monoclonal antibodies to the steroid receptor coactivator AIB1
    • Azorsa DO, Meltzer PS, (1999) Production and characterization of monoclonal antibodies to the steroid receptor coactivator AIB1. Hybridoma 18: 281-287.
    • (1999) Hybridoma , vol.18 , pp. 281-287
    • Azorsa, D.O.1    Meltzer, P.S.2
  • 42
    • 34447339121 scopus 로고    scopus 로고
    • HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer
    • Al-Kuraya K, Novotny H, Bavi P, Siraj AK, Uddin S, et al. (2007) HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer. J Clin Pathol 60: 768-772.
    • (2007) J Clin Pathol , vol.60 , pp. 768-772
    • Al-Kuraya, K.1    Novotny, H.2    Bavi, P.3    Siraj, A.K.4    Uddin, S.5
  • 43
    • 16644365463 scopus 로고    scopus 로고
    • HER2 analysis in breast cancer: reduced immunoreactivity in FISH non-informative cancer biopsies
    • Tapia C, Schraml P, Simon R, Al-Kuraya KS, Maurer R, et al. (2004) HER2 analysis in breast cancer: reduced immunoreactivity in FISH non-informative cancer biopsies. Int J Oncol 25: 1551-1557.
    • (2004) Int J Oncol , vol.25 , pp. 1551-1557
    • Tapia, C.1    Schraml, P.2    Simon, R.3    Al-Kuraya, K.S.4    Maurer, R.5
  • 44
    • 2942578063 scopus 로고    scopus 로고
    • A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    • Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, et al. (2004) A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 5: 607-616.
    • (2004) Cancer Cell , vol.5 , pp. 607-616
    • Ma, X.J.1    Wang, Z.2    Ryan, P.D.3    Isakoff, S.J.4    Barmettler, A.5
  • 45
    • 65449159747 scopus 로고    scopus 로고
    • A compact VEGF signature associated with distant metastases and poor outcomes
    • Hu Z, Fan C, Livasy C, He X, Oh DS, et al. (2009) A compact VEGF signature associated with distant metastases and poor outcomes. BMC Med 7: 9.
    • (2009) BMC Med , vol.7 , pp. 9
    • Hu, Z.1    Fan, C.2    Livasy, C.3    He, X.4    Oh, D.S.5
  • 46
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • van 't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3    He, Y.D.4    Hart, A.A.5
  • 47
    • 0030991201 scopus 로고    scopus 로고
    • The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism
    • Zhong H, SuYang H, Erdjument-Bromage H, Tempst P, Ghosh S, (1997) The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell 89: 413-424.
    • (1997) Cell , vol.89 , pp. 413-424
    • Zhong, H.1    SuYang, H.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 48
    • 77955171057 scopus 로고    scopus 로고
    • Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression
    • Teo H, Ghosh S, Luesch H, Ghosh A, Wong ET, et al. (2010) Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression. Nat Cell Biol 12: 758-767.
    • (2010) Nat Cell Biol , vol.12 , pp. 758-767
    • Teo, H.1    Ghosh, S.2    Luesch, H.3    Ghosh, A.4    Wong, E.T.5
  • 49
    • 0141703513 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
    • Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, et al. (2003) Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J Biol Chem 278: 36916-36923.
    • (2003) J Biol Chem , vol.278 , pp. 36916-36923
    • Sakurai, H.1    Suzuki, S.2    Kawasaki, N.3    Nakano, H.4    Okazaki, T.5
  • 50
    • 11244285329 scopus 로고    scopus 로고
    • Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
    • Buss H, Dörrie A, Schmitz ML, Hoffmann E, Resch K, et al. (2004) Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. J Biol Chem 279: 55633-55643.
    • (2004) J Biol Chem , vol.279 , pp. 55633-55643
    • Buss, H.1    Dörrie, A.2    Schmitz, M.L.3    Hoffmann, E.4    Resch, K.5
  • 52
    • 33747888160 scopus 로고    scopus 로고
    • Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer
    • Walser TC, Rifat S, Ma X, Kundu N, Ward C, et al. (2006) Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer. Cancer Res 66: 7701-7707.
    • (2006) Cancer Res , vol.66 , pp. 7701-7707
    • Walser, T.C.1    Rifat, S.2    Ma, X.3    Kundu, N.4    Ward, C.5
  • 53
    • 47749097074 scopus 로고    scopus 로고
    • The inflammatory chemokines CCL2 and CCL5 in breast cancer
    • Soria G, Ben-Baruch A, (2008) The inflammatory chemokines CCL2 and CCL5 in breast cancer. Cancer Lett 267: 271-285.
    • (2008) Cancer Lett , vol.267 , pp. 271-285
    • Soria, G.1    Ben-Baruch, A.2
  • 54
    • 40349113534 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer
    • Howe LR, (2007) Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer. Breast Cancer Res 9: 210.
    • (2007) Breast Cancer Res , vol.9 , pp. 210
    • Howe, L.R.1
  • 55
    • 79952996039 scopus 로고    scopus 로고
    • Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
    • Grivennikov SI, Karin M, (2011) Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 70: i104-108.
    • (2011) Ann Rheum Dis , vol.70
    • Grivennikov, S.I.1    Karin, M.2
  • 56
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.