The p35 human invariant chain in transgenic mice restores mature b cells in the absence of endogenous CD74

International Immunology

Volumn 24, Issue 10, 2012, Pages 645-660

  Genéve, Laetitia ^a   Ménard, Catherine ^a   Labrecque, Nathalie ^a,b   Thibodeau, Jacques ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Antigen presentation; Iip35; Invariant chain; MHC; Transgenic mouse

Indexed keywords

CD74 ANTIGEN; PEPTIDES AND PROTEINS; PROTEIN LIP35; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL MATURATION; CELL PERMEABILIZATION; ENDOSOME; HOMEOSTASIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SPLEEN;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTES; CELL DIFFERENTIATION; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC;

EID: 84867115491     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxs066     Document Type: Article

References (60)

1. Roche, P. A., Marks, M. S. and Cresswell, P. 1991. Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain. Nature 354:392.
2. Roche, P. A. and Cresswell, P. 1990. Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature 345:615.
3. Roche, P. A. and Cresswell, P. 1991. Proteolysis of the class IIassociated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc. Natl. Acad. Sci. U.S.A. 88:3150.
4. Bremnes, B., Madsen, T., Gedde-Dahl, M. and Bakke, O. 1994. An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization. J. Cell Sci. 107(Pt 7):2021.
5. Odorizzi, C. G., Trowbridge, I. S., Xue, L., Hopkins, C. R., Davis, C. D. and Collawn, J. F. 1994. Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment. J. Cell Biol. 126:317.
6. Pieters, J., Bakke, O. and Dobberstein, B. 1993. The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail. J. Cell Sci. 106(Pt 3):831.
7. Zecher, R., Ballhausen, W., Reske, K., Linder, D., Schluter, M. and Stirm, S. 1984. The invariant chains of mouse class II antigens: biochemical properties and molecular relationship. Eur. J. Immunol. 14:511.
8. Bijlmakers, M. E., Benaroch, P. and Ploegh, H. L. 1994. Mapping functional regions in the lumenal domain of the class II-associated invariant chain. J. Exp. Med. 180:623.
9. Hsing, L. C. and Rudensky, A. Y. 2005. The lysosomal cysteine proteases in MHC class II antigen presentation. Immunol. Rev. 207:229.
10. Kelly, A. P., Monaco, J. J., Cho, S. and Trowsdale, J. 1991. A new human HLA class II-related locus, DM. Nature 353:571.
11. Avva, R. R. and Cresswell, P. 1994. In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chainderived peptides. Immunity 1:763.
12. Riberdy, J. M., Avva, R. R., Geuze, H. J. and Cresswell, P. 1994. Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen- processing mutant cell lines. J. Cell Biol. 125:1225.
13. Berger, A. C. and Roche, P. A. 2009. MHC class II transport at a glance. J. Cell Sci. 122:1.
14. Viville, S., Neefjes, J. J., Lotteau, V. et al. 1993. Mice lacking the MHC class II-associated invariant chain. Cell 72:635.
15. Bikoff, E. K., Huang, L.-Y., Episkopou, V., van Meerwijk, J., Germain, R. N. and Robertson, E. J. 1993. Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression. J. Exp. Med. 177:1699.
16. Elliott, E. A., Drake, J. R., Amigorena, S. et al. 1994. The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules. J. Exp. Med. 179:681.
17. Dornmair, K., Rothenhausler, B. and McConnell, H. M. 1989. Structural intermediates in the reactions of antigenic peptides with MHC molecules. Cold Spring Harb. Symp. Quant. Biol. 54(Pt 1):409.
18. Cresswell, P. 1994. Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12:259.
19. Tourne, S., Nakano, N., Viville, S., Benoist, C. and Mathis, D. 1995. The influence of invariant chain on the positive selection of single T cell receptor specificities. Eur. J. Immunol. 25:1851.
20. Wong, P. and Rudensky, A. Y. 1996. Phenotype and function of CD4+ T cells in mice lacking invariant chain. J. Immunol. 156:2133.
21. Bikoff, E. K., Germain, R. N. and Robertson, E. J. 1995. Allelic differences affecting invariant chain dependency of MHC class II subunit assembly. Immunity. 2:301.
22. Shachar, I. and Flavell, R. A. 1996. Requirement for invariant chain in B cell maturation and function. Science 274:106.
23. Koonce, C. H. and Bikoff, E. K. 2004. Dissecting MHC class II export, B cell maturation, and DM stability defects in invariant chain mutant mice. J. Immunol. 173:3271.
24. Benlagha, K., Park, S. H., Guinamard, R. et al. 2004. Mechanisms governing B cell developmental defects in invariant chain-deficient mice. J. Immunol. 172:2076.
25. Matza, D., Kerem, A. and Shachar, I. 2003. Invariant chain, a chain of command. Trends Immunol. 24:264.
26. Labrecque, N., Madsen, L., Fugger, L., Benoist, C. and Mathis, D. 1999. Toxic MHC class II beta chains. Immunity 11:515.
27. Maehr, R., Kraus, M. and Ploegh, H. L. 2004. Mice deficient in invariant-chain and MHC class II exhibit a normal mature B2 cell compartment. Eur. J. Immunol. 34:2230.
28. Jayawardena-Wolf, J., Benlagha, K., Chiu, Y. H., Mehr, R. and Bendelac, A. 2001. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 15:897.
29. Sugita, M. and Brenner, M. B. 1995. Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments. J. Biol. Chem. 270:1443.
30. Ye, L., Liu, X., Rout, S. N. et al. 2008. The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments. J. Immunol. 181:2572.
31. Zwart, W., Peperzak, V., de Vries E., Keller, A. M. et al. 2010. The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells. J. Cell Sci. 123:3817.
32. Leng, L., Metz, C. N., Fang, Y. et al. 2003. MIF signal transduction initiated by binding to CD74. J. Exp. Med. 197:1467.
33. Beswick, E. J., Pinchuk, I. V., Minch, K. et al. 2006. The Helicobacter pylori urease B subunit binds to CD74 on gastric epithelial cells and induces NF-kappaB activation and interleukin-8 production. Infect. Immun. 74:1148.
34. Faure-Andre, G., Vargas, P., Yuseff, M. I. et al. 2008. Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science 322:1705.
35. Stumptner-Cuvelette, P., Morchoisne, S., Dugast, M. et al. 2001. HIV-1 Nef impairs MHC class II antigen presentation and surface expression. Proc. Natl. Acad. Sci. U.S.A. 98:12144.
36. Lennon-Dumenil, A. M., Roberts, R. A., Valentijn, K. et al. 2001. The p41 isoform of invariant chain is a chaperone for cathepsin L. EMBO J. 20:4055.
37. Strubin, M., Berte, C. and Mach, B. 1986. Alternative splicing and alternative initiation of translation explain the four forms of the Ia antigen-associated invariant chain. EMBO J. 5:3485.
38. Lamb, C. A. and Cresswell, P. 1992. Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes. J. Immunol. 148:3478.
39. Anderson, H. A., Bergstralh, D. T., Kawamura, T., Blauvelt, A. and Roche, P. A. 1999. Phosphorylation of the invariant chain by protein kinase C regulates MHC class II trafficking to antigen-processing compartments. J. Immunol. 163:5435.
40. Marks, M. S., Blum, J. S. and Cresswell, P. 1990. Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens. J. Cell Biol. 111:839.
41. Newcomb, J. R. and Cresswell, P. 1993. Structural analysis of proteolytic products of MHC class II-invariant chain complexes generated in vivo. J. Immunol. 151:4153.
42. Khalil, H., Brunet, A., Saba, I., Terra, R., Sekaly, R. P. and Thibodeau, J. 2003. The MHC class II beta chain cytoplasmic tail overcomes the invariant chain p35-encoded endoplasmic reticulum retention signal. Int. Immunol. 15:1249.
43. Anderson, H. A. and Roche, P. A. 1998. Phosphorylation regulates the delivery of MHC class II invariant chain complexes to antigen processing compartments. J. Immunol. 160:4850.
44. Kuwana, T., Peterson, P. A. and Karlsson, L. 1998. Exit of major histocompatibility complex class II-invariant chain p35 complexes from the endoplasmic reticulum is modulated by phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 95:1056.
45. Warmerdam, P. A., Long, E. O. and Roche, P. A. 1996. Isoforms of the invariant chain regulate transport of MHC class II molecules to antigen processing compartments. J. Cell Biol. 133:281.
46. Wang, K., Peterson, P. A. and Karlsson, L. 1997. Decreased endosomal delivery of major histocompatibility complex class II-invariant chain complexes in dynamin-deficient cells. J. Biol. Chem. 272:17055.
47. van Santen, H., Benoist, C. and Mathis, D. 2000. A cassette vector for high-level reporter expression driven by a hybrid invariant chain promoter in transgenic mice. J. Immunol. Methods 245:133.
48. Wraight, C. J., Van Endert, P., Moller, P. et al. 1990. Human major histocompatibility complex class II invariant chain is expressed on the cell surface. J. Biol. Chem. 265:5787.
49. Lacombe, M. H., Hardy, M. P., Rooney, J. and Labrecque, N. 2005. IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization. J. Immunol. 175:4400.
50. Glimcher, L. H., Polla, B. S., Poljak, A., Morton, C. C. and McKean, D. J. 1987. Murine class II (Ia) molecules associate with human invariant chain. J. Immunol. 138:1519.
51. Eastman, S., Deftos, M., DeRoos, P. C. et al. 1996. A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody. Eur. J. Immunol. 26:385.
52. Pierre, P., Shachar, I., Matza, D., Gatti, E., Flavell, R. A. and Mellman, I. 2000. Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cells. J. Exp. Med. 191:1057.
53. Sadegh-Nasseri, S. and Germain, R. N. 1991. A role for peptide in determining MHC class II structure. Nature 353:167.
54. Germain, R. N. and Hendrix, L. R. 1991. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353:134.
55. Honey, K., Forbush, K., Jensen, P. E. and Rudensky, A. Y. 2004. Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M. J. Immunol. 172:4142.
56. Zhu, Y., Rudensky, A. Y., Corper, A. L., Teyton, L. and Wilson, I. A. 2003. Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. J. Mol. Biol. 326:1157.
57. Beck, B. N., Buerstedde, J. M., Krco, C. J., Nilson, A. E., Chase, C. G. and McKean, D. J. 1986. Characterization of cell lines expressing mutant I-Ab and I-Ak molecules allows the definition of distinct serologic epitopes on A alpha and A beta polypeptides. J. Immunol. 136:2953.
58. Matza, D., Lantner, F., Bogoch, Y., Flaishon, L., Hershkoviz, R. and Shachar, I. 2002. Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity. Proc. Natl. Acad. Sci. U.S.A. 99:3018.
59. Kuwana, T., Peterson, P. A. and Karlsson, L. 1998. Exit of major histocompatibility complex class II-invariant chain p35 complexes from the endoplasmic reticulum is modulated by phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 95:1056.
60. Su, T. T., Guo, B. and Rawlings, D. J. 2002. Emerging roles for PKC isoforms in immune cell function. Mol. Interv. 2:141.