The metastatic microenvironment: Brain-derived soluble factors alter the malignant phenotype of cutaneous and brain-metastasizing melanoma cells

International Journal of Cancer

Volumn 131, Issue 11, 2012, Pages 2509-2518

  Klein, Anat ^a   Sagi Assif, Orit ^a   Izraely, Sivan ^a   Meshel, Tsipi ^a   Pasmanik Chor, Metsada ^a   Nahmias, Clara ^b,c,d   Couraud, Pierre Olivier ^b,c,d   Erez, Neta ^a   Hoon, Dave S B ^e   Witz, Isaac P ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b INSTITUT COCHIN   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e JOHN WAYNE CANCER INSTITUTE   (United States)

Author keywords

brain metastasis; melanoma; microenvironment

Indexed keywords

BRAIN DERIVED SOLUBLE FACTOR; BRAIN PROTEIN; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN METASTASIS; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL MIGRATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MELANOMA CELL; METASTASIS POTENTIAL; METASTATIC MELANOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; TISSUE CULTURE; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; UPREGULATION;

ANIMALS; APOPTOSIS; BRAIN; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL MOVEMENT; ENDOTHELIAL CELLS; HUMANS; MALE; MELANOMA; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM METASTASIS; PHENOTYPE; RECEPTORS, CCR3; RECEPTORS, CCR4; S PHASE; SKIN NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; TUMOR MICROENVIRONMENT; UP-REGULATION;

EID: 84867093457     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27552     Document Type: Article

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