Evasion of human innate immunity without antagonizing TLR4 by mutant Salmonella enterica serovar Typhimurium having penta-acylated lipid A

Innate Immunity

Volumn 18, Issue 5, 2012, Pages 764-773

  Matsuura, Motohiro ^a   Kawasaki, Kiyoshi ^b   Kawahara, Kazuyoshi ^c   Mitsuyama, Masao ^a  

^a KYOTO UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c KANTO GAKUIN UNIVERSITY   (Japan)

Author keywords

Bacterial evasion; human innate immunity; lipopolysaccharide; penta acylated lipid A; Salmonella

Indexed keywords

LIPID A; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM;

ACETYLATION; ANTIBODIES, BLOCKING; CYTOKINES; HUMANS; IMMUNE EVASION; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; LIPID A; MACROPHAGE ACTIVATION; MACROPHAGES; MUTATION; SALMONELLA TYPHI; TOLL-LIKE RECEPTOR 4; TYPHOID FEVER; U937 CELLS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; TETRA;

EID: 84867088982     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425912440599     Document Type: Article

References (37)

1. Miyake K. Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. Trends Microbiol. 2004 ; 12: 186-192
2. Shimazu R, Akashi S, Ogata H, et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med. 1999 ; 189: 1777-1782
3. Nagai Y, Akashi S, Nagafuku M, et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol. 2002 ; 3: 667-672
4. Akashi S, Saitoh S, Wakabayashi Y, et al. Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J Exp Med. 2003 ; 198: 1035-1042
5. Visintin A, Latz E, Monks BG, et al. Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. J Biol Chem. 2003 ; 278: 48313-48320
6. Golenbock DT, Hampton RY, Qureshi N, et al. Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. J Biol Chem. 1991 ; 266: 19490-19498
7. Matsuura M, Kiso M, Hasegawa A. Activity of monosaccharide lipid A analogues in human monocytic cells as agonists or antagonists of bacterial lipopolysaccharide. Infect Immun. 1999 ; 67: 6286-6292
8. Galanos C, Lüderitz O, Rietschel ET, et al. Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. Eur J Biochem. 1985 ; 148: 1-5
9. Homma JY, Matsuura M, Kanegasaki S, et al. Structural requirements of lipid A responsible for the functions: a study with chemically synthesized lipid A and its analogues. J Biochem. 1985 ; 98: 395-406
10. Kotani S, Takada H, Tsujimoto M, et al. Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant. Infect Immun. 1985 ; 49: 225-237
11. Raetz CR, Whitfield C. Lipopolysaccharide endotoxins. Annu Rev Biochem. 2002 ; 71: 635-700
12. Kawahara K, Tsukano H, Watanabe H, et al. Modification of the structure and activity of lipid A in Yersinia pestis lipopolysaccharide by growth temperature. Infect Immun. 2002 ; 70: 4092-4098
13. Montminy SW, Khan N, McGrath S, et al. Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response. Nat Immunol. 2006 ; 7: 1066-1073
14. Phillips NJ, Schilling B, McLendon MK, et al. Novel modification of lipid A of Francisella tularensis. Infect Immun. 2004 ; 72: 5340-5348
15. Vinogradov E, Perry MB, Conlan JW. Structural analysis of Francisella tularensis lipopolysaccharide. Eur J Biochem. 2002 ; 269: 6112-6118
16. Lepper PM, Triantafilou M, Schumann C, et al. Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4. Cell Microbiol. 2005 ; 7: 519-528
17. Coats SR, Reife RA, Bainbridge BW, et al. Porphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells. Infect Immun. 2003 ; 71: 6799-6807
18. Vogel SN, Johnson D, Perera PY, et al. Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation. J Immunol. 1999 ; 162: 5666-5670
19. O'Brien AD, Metcalf ES, Rosenstreich DL. Defect in macrophage effector function confers Salmonella typhimurium susceptibility on C3H/HeJ mice. Cell Immunol. 1982 ; 67: 325-333
20. Jarvik T, Smillie C, Groisman EA, et al. Short-term signatures of evolutionary change in the Salmonella enterica serovar typhimurium 14028 genome. J Bacteriol. 2010 ; 192: 560-567
21. Datsenko KA, Wanner BL. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA. 2000 ; 97: 6640-6645
22. Kawasaki K, China K, Nishijima M. Release of the lipopolysaccharide deacylase PagL from latency compensates for a lack of lipopolysaccharide aminoarabinose modification-dependent resistance to the antimicrobial peptide polymyxin B in Salmonella enterica. J Bacteriol. 2007 ; 189: 4911-4919
23. Davis RW, Bolstein D, Roth JR Advanced bacterial genetics: A manual for genetic engineering. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press ; 1980 :
24. Yi EC, Hackett M. Rapid isolation method for lipopolysaccharide and lipid A from gram-negative bacteria. Analyst. 2000 ; 125: 651-656
25. Westphal O, Lüderitz O and Bister F. Uber die Extraktion von Bakterien mit Phenol/Wasser. Z Naturforsch 1952; Teil B 7: 148-155.
26. Westphal O, Jann K. Bacterial lipopolysaccharides: extraction with phenol-water and further application of the procedure. Methods Carbohydro Chem. 1965 ; 234: 1945-1950
27. Akashi S, Ogata H, Kirikae F, et al. Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2. Biochem Biophys Res Commun. 2000 ; 268: 172-177
28. Lien E, Sellati TJ, Yoshimura A, et al. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem. 1999 ; 274: 33419-33425
29. Guo L, Lim KB, Poduje CM, et al. Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides. Cell. 1998 ; 95: 189-198
30. Bishop RE, Gibbons HS, Guina T, et al. Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria. EMBO J. 2000 ; 19: 5071-5080
31. Raetz CR, Reynolds CM, Trent MS, et al. Lipid A modification systems in gram-negative bacteria. Annu Rev Biochem. 2007 ; 76: 295-329
32. Matsuura M, Takahashi H, Watanabe H, et al. Immunomodulatory effects of Yersinia pestis lipopolysaccharides on human macrophages. Clin Vaccine Immunol. 2010 ; 17: 49-55
33. Jones BD, Nichols WA, Gibson BW, et al. Study of the role of the htrB gene in Salmonella typhimurium virulence. Infect Immun. 1997 ; 65: 4778-4783
34. Kalupahana R, Emilianus AR, Maskell D, et al. Salmonella enterica serovar Typhimurium expressing mutant lipid A with decreased endotoxicity causes maturation of murine dendritic cells. Infect Immun. 2003 ; 71: 6132-6140
35. Vorachek-Warren MK, Ramirez S, Cotter RJ, et al. A triple mutant of Escherichia coli lacking secondary acyl chains on lipid A. J Biol Chem. 2002 ; 277: 14194-14205
36. Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol. 2005 ; 17: 338-344
37. Fransen F, Heckenberg SG, Hamstra HJ, et al. Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy. PLoS Pathog. 2009 ; 5: e1000396 - e1000396