CCl4-induced hepatotoxicity: Protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Khan, Rahmat A ^a,b   Khan, Muhammad R ^b   Sahreen, Sumaira ^b,c  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY BANNU   (Pakistan)

^b QUAID I AZAM UNIVERSITY   (Pakistan)

^c PAKISTAN MUSEUM OF NATURAL HISTORY   (Pakistan)

Author keywords

Antioxidant enzymes; CYP 2E1; Hepatotoxicity; p53; Rutin

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CHOLESTEROL; CYTOCHROME P450 2E1; ENZYME; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MOLECULAR MARKER; PROTEIN P53; RUTOSIDE; TRIACYLGLYCEROL; ANTIOXIDANT; LIPID; PLANT EXTRACT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; LIPID ANALYSIS; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; DRUG EFFECT; ENZYMOLOGY; LIVER; METABOLISM; PHYTOTHERAPY; SPRAGUE DAWLEY RAT; TOXIC HEPATITIS;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CYTOCHROME P-450 CYP2E1; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ENZYMES; LIPID PEROXIDATION; LIPIDS; LIVER; MALE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RUTIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84867087393     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-178     Document Type: Article

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