-
1
-
-
2342629325
-
Bcr-Abl kinase mutations and drug resistance to imatinib (STI571) in chronic myelogenous leukemia
-
Cowan-Jacob SW, Guez V, Fendrich G, Griffin JD, Fabbro D, et al. (2004) Bcr-Abl kinase mutations and drug resistance to imatinib (STI571) in chronic myelogenous leukemia. Mini Rev Med Chem 4: 285-299.
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 285-299
-
-
Cowan-Jacob, S.W.1
Guez, V.2
Fendrich, G.3
Griffin, J.D.4
Fabbro, D.5
-
2
-
-
34247329753
-
Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells
-
Jorgensen HG, Allen EK, Jordanides NE, Mountford JC, Holyoake TL, (2007) Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells. Blood 109: 4016-4019.
-
(2007)
Blood
, vol.109
, pp. 4016-4019
-
-
Jorgensen, H.G.1
Allen, E.K.2
Jordanides, N.E.3
Mountford, J.C.4
Holyoake, T.L.5
-
3
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 year: the prospective, multicentre Stop Imatinib (STIM) trial
-
Mahon FX, Rea D, Guilhot J, Guilhot F, Huguet F, et al. (2010) Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 year: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 11: 1029-1035.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
Guilhot, F.4
Huguet, F.5
-
4
-
-
79952081141
-
Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemia
-
Cortes J, Hochhaus A, Hughes T, Kantarjian H, (2011) Front-line and salvage therapies with tyrosine kinase inhibitors and other treatments in chronic myeloid leukemia. J Clin Oncol 29: 524-531.
-
(2011)
J Clin Oncol
, vol.29
, pp. 524-531
-
-
Cortes, J.1
Hochhaus, A.2
Hughes, T.3
Kantarjian, H.4
-
5
-
-
0035313251
-
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents
-
Kano Y, Akutsu M, Tsunoda S, Mano H, Sato Y, et al. (2001) In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents. Blood 97: 1999-2007.
-
(2001)
Blood
, vol.97
, pp. 1999-2007
-
-
Kano, Y.1
Akutsu, M.2
Tsunoda, S.3
Mano, H.4
Sato, Y.5
-
6
-
-
0036715327
-
Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells
-
Yu C, Krystal G, Dent P, Grant S, (2002) Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells. Clin Cancer Res 8: 2976-2984.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2976-2984
-
-
Yu, C.1
Krystal, G.2
Dent, P.3
Grant, S.4
-
7
-
-
30744446226
-
Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy
-
Borthakur G, Kantarjian H, Daley G, Talpaz M, O'Brien S, et al. (2006) Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy. Cancer 106: 346-352.
-
(2006)
Cancer
, vol.106
, pp. 346-352
-
-
Borthakur, G.1
Kantarjian, H.2
Daley, G.3
Talpaz, M.4
O'Brien, S.5
-
8
-
-
67650888562
-
Synergy between proteasome inhibitors and imatinib mesylate in chronic myeloid leukemia
-
Hu Z, Pan XF, Wu FQ, Ma LY, Liu DP, et al. (2009) Synergy between proteasome inhibitors and imatinib mesylate in chronic myeloid leukemia. PLoS One 4: e6257.
-
(2009)
PLoS One
, vol.4
-
-
Hu, Z.1
Pan, X.F.2
Wu, F.Q.3
Ma, L.Y.4
Liu, D.P.5
-
9
-
-
79953907017
-
Combination of the Hedgehog Pathway Inhibitor LDE225 and Nilotinib eliminates Chronic Myeloid Leukemia Stem and Progenitor Cells
-
Irvine DA, Zhang B, Allan EK, Holyoake TL, Dorsch M, et al. (2009) Combination of the Hedgehog Pathway Inhibitor LDE225 and Nilotinib eliminates Chronic Myeloid Leukemia Stem and Progenitor Cells. Blood (ASH Annual Meeting abstracts) 114: 1428.
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, pp. 1428
-
-
Irvine, D.A.1
Zhang, B.2
Allan, E.K.3
Holyoake, T.L.4
Dorsch, M.5
-
10
-
-
77952105211
-
Targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate
-
Zhang B, Strauss AC, Chu S, Li M, Ho Y, et al. (2010) Targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate. Cancer Cell 17: 427-442.
-
(2010)
Cancer Cell
, vol.17
, pp. 427-442
-
-
Zhang, B.1
Strauss, A.C.2
Chu, S.3
Li, M.4
Ho, Y.5
-
11
-
-
0018414519
-
Pharmacological investigations with compounds of chamomile II. New investigations on the antiphlogistic effects of (-)-alpha bisabolol and bisabolol oxides
-
Jakovlev V, Isaac O, Thiemer K, Kunde R, (1979) Pharmacological investigations with compounds of chamomile II. New investigations on the antiphlogistic effects of (-)-alpha bisabolol and bisabolol oxides. Planta Med 35: 125-140.
-
(1979)
Planta Med
, vol.35
, pp. 125-140
-
-
Jakovlev, V.1
Isaac, O.2
Thiemer, K.3
Kunde, R.4
-
12
-
-
10744228702
-
Alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells
-
Cavalieri E, Mariotto S, Fabrizi C, de Prati AC, Gottardo R, et al. (2004) Alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells. Biochem Biophys Res Commun 315: 589-594.
-
(2004)
Biochem Biophys Res Commun
, vol.315
, pp. 589-594
-
-
Cavalieri, E.1
Mariotto, S.2
Fabrizi, C.3
de Prati, A.C.4
Gottardo, R.5
-
13
-
-
79954590785
-
Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells
-
Cavalieri E, Rigo A, Bonifacio M, de Prati AC, Guardalben E, et al. (2011) Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells. J Transl Med 9: 45.
-
(2011)
J Transl Med
, vol.9
, pp. 45
-
-
Cavalieri, E.1
Rigo, A.2
Bonifacio, M.3
de Prati, A.C.4
Guardalben, E.5
-
14
-
-
48149111801
-
Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid
-
Darra E, Abdel-Azeim S, Manara A, Shoji K, Marechal JD, et al. (2008) Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid. Arch Biochem Biophys 476: 113-123.
-
(2008)
Arch Biochem Biophys
, vol.476
, pp. 113-123
-
-
Darra, E.1
Abdel-Azeim, S.2
Manara, A.3
Shoji, K.4
Marechal, J.D.5
-
15
-
-
34548042324
-
Epigenetic DNA-methylation regulation of genes coding for lipid raft-associated components: a role for raft proteins in cell transformation and cancer progression
-
Patra SK, Bettuzzi S, (2007) Epigenetic DNA-methylation regulation of genes coding for lipid raft-associated components: a role for raft proteins in cell transformation and cancer progression. Oncol Rep 17: 1279-1290.
-
(2007)
Oncol Rep
, vol.17
, pp. 1279-1290
-
-
Patra, S.K.1
Bettuzzi, S.2
-
16
-
-
68149156097
-
Involvement of the mitochondrial permeability transition pore opening in α-bisabolol induced apoptosis
-
Cavalieri E, Bergamini C, Mariotto S, Leoni S, Perbellini L, et al. (2009) Involvement of the mitochondrial permeability transition pore opening in α-bisabolol induced apoptosis. FEBS Journal 276: 3990-4000.
-
(2009)
FEBS Journal
, vol.276
, pp. 3990-4000
-
-
Cavalieri, E.1
Bergamini, C.2
Mariotto, S.3
Leoni, S.4
Perbellini, L.5
-
17
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
Eskes R, Desagher S, Antonsson B, Martinou JC, (2000) Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 20: 929-935.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 929-935
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
Martinou, J.C.4
-
18
-
-
69349087479
-
Anti- and pro-tumor functions of autophagy
-
Morselli E, Galluzzi L, Kepp O, Vicencio JM, Criollo A, et al. (2009) Anti- and pro-tumor functions of autophagy. Biochim Biophys Acta 1793: 1524-1532.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
-
19
-
-
0033106398
-
Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor expression by acute myeloid leukemia cells
-
Vinante F, Rigo A, Papini E, Cassatella MA, Pizzolo G, (1999) Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor expression by acute myeloid leukemia cells. Blood 93: 1715-1723.
-
(1999)
Blood
, vol.93
, pp. 1715-1723
-
-
Vinante, F.1
Rigo, A.2
Papini, E.3
Cassatella, M.A.4
Pizzolo, G.5
-
20
-
-
0033231097
-
Granulocyte-macrophage colony-stimulating factor induces expression of heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor and sensitivity to diphtheria toxin in human neutrophils
-
Vinante F, Marchi M, Rigo A, Scapini P, Pizzolo G, et al. (1999) Granulocyte-macrophage colony-stimulating factor induces expression of heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor and sensitivity to diphtheria toxin in human neutrophils. Blood 94: 3169-3177.
-
(1999)
Blood
, vol.94
, pp. 3169-3177
-
-
Vinante, F.1
Marchi, M.2
Rigo, A.3
Scapini, P.4
Pizzolo, G.5
-
21
-
-
84859937526
-
CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin
-
Rigo A, Gottardi M, Damiani E, Bonifacio M, Ferrarini I, et al. (2012) CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin. PLoS One 7: e34432.
-
(2012)
PLoS One
, vol.7
-
-
Rigo, A.1
Gottardi, M.2
Damiani, E.3
Bonifacio, M.4
Ferrarini, I.5
-
22
-
-
0000994406
-
Analysis of combined drug effects: a new look at a very old problem
-
Chou TC, Talalay P, (1984) Analysis of combined drug effects: a new look at a very old problem. Trends Pharmacol Sci 4: 450-454.
-
(1984)
Trends Pharmacol Sci
, vol.4
, pp. 450-454
-
-
Chou, T.C.1
Talalay, P.2
-
23
-
-
0031939746
-
Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase
-
Imai H, Narashima K, Arai M, Sakamoto H, Chiba N, et al. (1998) Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase. J Biol Chem 273: 1990-1997.
-
(1998)
J Biol Chem
, vol.273
, pp. 1990-1997
-
-
Imai, H.1
Narashima, K.2
Arai, M.3
Sakamoto, H.4
Chiba, N.5
-
24
-
-
70349480990
-
Validation of a high-performance liquid chromatography method for the determination of (-)-α-bisabolol from particulate systems
-
Sao Pedro A, Detoni C, Ferreira D, Cabral-Albuquerque E, Sarmento B, (2009) Validation of a high-performance liquid chromatography method for the determination of (-)-α-bisabolol from particulate systems. Biomed Chromatogr 23: 966-972.
-
(2009)
Biomed Chromatogr
, vol.23
, pp. 966-972
-
-
Sao Pedro, A.1
Detoni, C.2
Ferreira, D.3
Cabral-Albuquerque, E.4
Sarmento, B.5
-
25
-
-
0037474471
-
Assay of mitochondrial respiratory chain complex I in human lymphocytes and cultured skin fibroblasts
-
Chretien D, Bénit P, Chol M, Lebon S, Rötig A, et al. (2003) Assay of mitochondrial respiratory chain complex I in human lymphocytes and cultured skin fibroblasts. Biochem Biophys Res Commun 301: 222-224.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 222-224
-
-
Chretien, D.1
Bénit, P.2
Chol, M.3
Lebon, S.4
Rötig, A.5
-
26
-
-
79956191110
-
Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation
-
Butturini E, Cavalieri E, Carcereri de Prati A, Darra E, Rigo A, et al. (2011) Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation. PLoS One 6: e20174.
-
(2011)
PLoS One
, vol.6
-
-
Butturini, E.1
Cavalieri, E.2
Carcereri de Prati, A.3
Darra, E.4
Rigo, A.5
-
27
-
-
77952327851
-
In vivo effect of alpha-bisabolol, a non toxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice
-
Costarelli L, Malavolta M, Giacconi R, Cipriano C, Gasparini N, et al. (2010) In vivo effect of alpha-bisabolol, a non toxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice. Oncol Res 18: 409-418.
-
(2010)
Oncol Res
, vol.18
, pp. 409-418
-
-
Costarelli, L.1
Malavolta, M.2
Giacconi, R.3
Cipriano, C.4
Gasparini, N.5
-
28
-
-
81855194120
-
Antitumor effect of α-bisabolol against pancreatic cancer
-
Seki T, Kokuryo T, Yokoyama Y, Suzuki H, Itatsu K, et al. (2011) Antitumor effect of α-bisabolol against pancreatic cancer. Cancer Sci 102: 2199-2205.
-
(2011)
Cancer Sci
, vol.102
, pp. 2199-2205
-
-
Seki, T.1
Kokuryo, T.2
Yokoyama, Y.3
Suzuki, H.4
Itatsu, K.5
-
29
-
-
66449122303
-
Targeting autophagy potentiates tyrosine kinase inhibito-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
-
Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, et al. (2009) Targeting autophagy potentiates tyrosine kinase inhibito-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 119: 1109-1123.
-
(2009)
J Clin Invest
, vol.119
, pp. 1109-1123
-
-
Bellodi, C.1
Lidonnici, M.R.2
Hamilton, A.3
Helgason, G.V.4
Soliera, A.R.5
-
31
-
-
34548188741
-
Self-eating and self-killing: crosstalk between autophagy and apoptosis
-
Maiuri MC, Zalckvar E, Kimchi A, Kroemer G, (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
|