Diet-induced metabolic change induces estrogen-independent allometric mammary growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 40, 2012, Pages 16294-16299

  Berryhill, Grace E ^a   Gloviczki, Julia M ^a   Trott, Josephine F ^a   Aimo, Lucila ^a   Kraft, Jana ^b   Cardiff, Robert D ^a   Paul, Carly T ^a   Petrie, Whitney K ^a   Lock, Adam L ^c   Hovey, Russell C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONJUGATED LINOLEIC ACID; ESTROGEN; ESTROGEN RECEPTOR; ROSIGLITAZONE; SOMATOMEDIN C RECEPTOR; VIRUS T ANTIGEN;

ALLOMETRY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; ESTROGEN SYNTHESIS; FEMALE; HYPERINSULINEMIA; ISOMER; MALE; MAMMARY GLAND; MAMMARY GLAND GROWTH; METABOLIC SYNDROME X; MOUSE; NONHUMAN; ORGAN GROWTH; OVARIECTOMY; OVARY FUNCTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMAL FEED; ANIMALS; BLOTTING, WESTERN; CORTICOSTERONE; DNA PRIMERS; FATTY ACIDS; FEMALE; HISTOLOGICAL TECHNIQUES; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LEAST-SQUARES ANALYSIS; LINOLEIC ACIDS, CONJUGATED; MAMMARY GLANDS, ANIMAL; METABOLIC SYNDROME X; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; THIAZOLIDINEDIONES;

MUS; POLYOMAVIRUS;

EID: 84867055650     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210527109     Document Type: Article

References (47)

1. Michels KB, Rosner BA, Chumlea WC, Colditz GA, Willett WC (2006) Preschool diet and adult risk of breast cancer. Int J Cancer 118:749-754. (Pubitemid 43076027)
2. Ruder EH, Dorgan JF, Kranz S, Kris-Etherton PM, Hartman TJ (2008) Examining breast cancer growth and lifestyle risk factors: Early life, childhood, and adolescence. Clin Breast Cancer 8:334-342.
3. Baer HJ, et al. (2005) Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: A prospective cohort study. Breast Cancer Res 7:R314-R325.
4. Berkey CS, Frazier AL, Gardner JD, Colditz GA (1999) Adolescence and breast carcinoma risk. Cancer 85:2400-2409. (Pubitemid 29244849)
5. Himes JH (2006) Examining the evidence for recent secular changes in the timing of puberty in US children in light of increases in the prevalence of obesity. Mol Cell Endocrinol 254-255:13-21.
6. Lee JM, et al. (2007) Weight status in young girls and the onset of puberty. Pediatrics 119:e624-e630. (Pubitemid 46407535)
7. Aksglaede L, Sørensen K, Petersen JH, Skakkebaek NE, Juul A (2009) Recent decline in age at breast development: The Copenhagen Puberty Study. Pediatrics 123:e932-e939.
8. Ronckers CM, Erdmann CA, Land CE (2005) Radiation and breast cancer: A review of current evidence. Breast Cancer Res 7:21-32. (Pubitemid 40214533)
9. Haslam SZ (1979) Age as a modifying factor of 7,12-dimethylbenz(a) anthracene-induced mammary carcinogenesis in the Lewis rat. Int J Cancer 23:374-379.
10. Elias SG, Peeters PH, Grobbee DE, van Noord PA (2004) Breast cancer risk after caloric restriction during the 1944-1945 Dutch famine. J Natl Cancer Inst 96:539-546. (Pubitemid 38559578)
11. Berkey CS, et al. (2011) Prospective study of growth and development in older girls and risk of benign breast disease in young women. Cancer 117:1612-1620.
12. Hovey RC, Trott JF, Vonderhaar BK (2002) Establishing a framework for the functional mammary gland: From endocrinology to morphology. J Mammary Gland Biol Neoplasia 7:17-38. (Pubitemid 38420779)
13. Flux DS (1954) Growth of the mammary duct system in intact and ovariectomized mice of the CHI strain. J Endocrinol 11:223-237.
14. Ruan W, Kleinberg DL (1999) Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. Endocrinology 140:5075-5081.
15. Hovey RC, Aimo L (2010) Diverse and active roles for adipocytes during mammary gland growth and function. J Mammary Gland Biol Neoplasia 15:279-290.
16. Grundy SM, Brewer HB, Jr., Cleeman JI, Smith SC, Jr., Lenfant C; American Heart Association; National Heart, Lung, and Blood Institute (2004) Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 109:433-438. (Pubitemid 38133916)
17. Bremer AA, Mietus-Snyder M, Lustig RH (2012) Toward a unifying hypothesis of metabolic syndrome. Pediatrics 129:557-570.
18. Jung MO, Yoon SH, Jung MY (2001) Effects of temperature and agitation rate on the formation of conjugated linoleic acids in soybean oil during hydrogenation process. J Agric Food Chem 49:3010-3016.
19. Lock AL, Bauman DE (2004) Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health. Lipids 39:1197-1206.
20. Halade GV, Rahman MM, Fernandes G (2010) Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice. J Nutr Biochem 21:332-337.
21. Clément L, et al. (2002) Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J Lipid Res 43:1400-1409.
22. Poirier H, Shapiro JS, Kim RJ, Lazar MA (2006) Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue. Diabetes 55:1634-1641. (Pubitemid 44324115)
23. Larsen TM, Toubro S, Astrup A (2003) Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: Evidence from animal and human studies. J Lipid Res 44:2234-2241. (Pubitemid 38082481)
24. Tricon S, et al. (2004) Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. Am J Clin Nutr 80:614-620. (Pubitemid 41115525)
25. Hovey RC, et al. (2005) Effects of neonatal exposure to diethylstilbestrol, tamoxifen, and toremifene on the BALB/c mouse mammary gland. Biol Reprod 72:423-435. (Pubitemid 40129719)
26. Ulanet DB, Ludwig DL, Kahn CR, Hanahan D (2010) Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci USA 107:10791-10798.
27. Guy CT, Cardiff RD, Muller WJ (1992) Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease. Mol Cell Biol 12:954-961.
28. Walden PD, Ruan W, Feldman M, Kleinberg DL (1998) Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development. Endocrinology 139:659-662. (Pubitemid 28513216)
29. Ruan W, Catanese V, Wieczorek R, Feldman M, Kleinberg DL (1995) Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid. Endocrinology 136:1296-1302.
30. Feldman M, Ruan W, Tappin I, Wieczorek R, Kleinberg DL (1999) The effect of GH on estrogen receptor expression in the rat mammary gland. J Endocrinol 163:515-522. (Pubitemid 30033747)
31. Ruan W, Monaco ME, Kleinberg DL (2005) Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action. Endocrinology 146:1170-1178. (Pubitemid 40289306)
32. Ip MM, et al. (2007) The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis 28:1269-1276. (Pubitemid 47062687)
33. Foote MR, Giesy SL, Bernal-Santos G, Bauman DE, Boisclair YR (2010) t10,c12-CLA decreases adiposity in peripubertal mice without dose-related detrimental effects on mammary development, inflammation status, and metabolism. Am J Physiol Regul Integr Comp Physiol 299:R1521-R1528.
34. Rogers IS, et al. (2010) Diet throughout childhood and age at menarche in a contemporary cohort of British girls. Public Health Nutr 13:2052-2063.
35. Fuemmeler BF, Pendzich MK, Tercyak KP (2009) Weight, dietary behavior, and physical activity in childhood and adolescence: Implications for adult cancer risk. Obes Facts 2:179-186.
36. Boyd NF, et al. (2003) Dietary fat and breast cancer risk revisited: A meta-analysis of the published literature. Br J Cancer 89:1672-1685. (Pubitemid 37464139)
37. Wang J, John EM, Horn-Ross PL, Ingles SA (2008) Dietary fat, cooking fat, and breast cancer risk in a multiethnic population. Nutr Cancer 60:492-504. (Pubitemid 351918541)
38. Ibarra-Drendall C, Dietze EC, Seewaldt VL (2011) Metabolic syndrome and breast cancer risk: Is there a role for metformin? Curr Breast Cancer Rep 3:142-150.
39. Rose DP, Haffner SM, Baillargeon J (2007) Adiposity, the metabolic syndrome, and breast cancer in African-American and white American women. Endocr Rev 28:763-777. (Pubitemid 350294295)
40. Novosyadlyy R, et al. (2010) Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes. Cancer Res 70:741-751.
41. Gunter MJ, et al. (2009) Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 101:48-60.
42. Currie CJ, et al. (2012) Mortality after incident cancer in people with and without type 2 diabetes: Impact of metformin on survival. Diabetes Care 35:299-304.
43. Rowzee AM, Ludwig DL, Wood TL (2009) Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells. Endocrinology 150:3611-3619.
44. Bonnette SG, Hadsell DL (2001) Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds. Endocrinology 142:4937-4945. (Pubitemid 33022370)
45. Fox EM, et al. (2011) A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. Cancer Res 71:6773-6784.
46. Pollak M (2012) The insulin and insulin-like growth factor receptor family in neoplasia: An update. Nat Rev Cancer 12:159-169.
47. Gallagher EJ, LeRoith D (2011) Minireview: IGF, insulin, and cancer. Endocrinology 152:2546-2551.