Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis

Food and Chemical Toxicology

Volumn 50, Issue 12, 2012, Pages 4333-4339

  Lin, Ming Wei ^a,b   Lin, An Shen ^a   Wu, Deng Chyang ^b   Wang, Sophie S W ^b   Chang, Fang Rong ^a,b   Wu, Yang Chang ^a,c,d   Huang, Yaw Bin ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Anti proliferation; Apoptosis; ERK1 2; Euphol; Human gastric cancer

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CASPASE 3; CYCLIN B1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; EUPHOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2;

ANTIINFLAMMATORY ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; EUPHORBIA; EUPHORBIA TIRUCALLI; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STOMACH CANCER; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN B1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; EUPHORBIA; HUMANS; LANOSTEROL; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; UP-REGULATION;

EUPHORBIA TIRUCALLI;

EID: 84867051119     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.029     Document Type: Article

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