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Volumn 3, Issue , 2012, Pages

Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE QUADRUPLEX; PROTEIN P16; PROTEIN P21; SINGLE WALLED NANOTUBE; TELOMERASE; TELOMERE BINDING PROTEIN;

EID: 84867022915     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2091     Document Type: Article
Times cited : (140)

References (59)
  • 1
    • 84866979733 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange, T. How telomeres solve the end-protection problem. Science 336, 593-597 (2009).
    • (2009) Science , vol.336 , pp. 593-597
    • De Lange, T.1
  • 3
    • 1842683257 scopus 로고    scopus 로고
    • T-loops and the origin of telomeres
    • DOI 10.1038/nrm1359
    • de Lange, T. T-loops and the origin of telomeres. Nat. Rev. Mol. Cell Biol 5, 323-329 (2004). (Pubitemid 38480613)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.4 , pp. 323-329
    • De Lange, T.1
  • 4
    • 1642523697 scopus 로고    scopus 로고
    • Indecent exposure: When telomeres become uncapped
    • Ferreira, M. G., Miller, K. M. & Cooper, J. P. Indecent exposure: when telomeres become uncapped. Mol. Cell 13, 7-16 (2004).
    • (2004) Mol. Cell , vol.13 , pp. 7-16
    • Ferreira, M.G.1    Miller, K.M.2    Cooper, J.P.3
  • 5
    • 0025877846 scopus 로고
    • Inhibition of telomerase by G-quartet structures
    • Zahler, A. M., Williamson, J. R., Cech, W. R. & Prescott, D. M. Inhibition of telomerase by G-quartet structures. Nature 350, 718-720 (1991).
    • (1991) Nature , vol.350 , pp. 718-720
    • Zahler, A.M.1    Williamson, J.R.2    Cech, W.R.3    Prescott, D.M.4
  • 6
    • 67649833785 scopus 로고    scopus 로고
    • G-quadruplex nucleic acids as therapeutic targets
    • Balasubramanian, S. & Neidle, S. G-quadruplex nucleic acids as therapeutic targets. Curr. Opin. Chem. Biol. 13, 345-353 (2009).
    • (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 345-353
    • Balasubramanian, S.1    Neidle, S.2
  • 7
  • 8
    • 77955809107 scopus 로고    scopus 로고
    • Making sense of G-quadruplex and i-motif functions in oncogene promoters
    • Brooks, T. A., Kendrick, S. & Hurley, L. H. Making sense of G-quadruplex and i-motif functions in oncogene promoters. FEBS J. 277, 3459-3469 (2010).
    • (2010) FEBS J. , vol.277 , pp. 3459-3469
    • Brooks, T.A.1    Kendrick, S.2    Hurley, L.H.3
  • 11
    • 33747093424 scopus 로고    scopus 로고
    • Carbon nanotubes selective destabilization of duplex and triplex DNA and inducing B-A transition in solution
    • DOI 10.1093/nar/gkl513
    • Li, X., Peng, Y. & Qu, X. Carbon nanotubes selective destabilization of duplex and triplex DNA and inducing B-A transition in solution. Nucleic Acids Res. 34, 3670-3676 (2006). (Pubitemid 44400416)
    • (2006) Nucleic Acids Research , vol.34 , Issue.13 , pp. 3670-3676
    • Li, X.1    Peng, Y.2    Qu, X.3
  • 12
    • 44949094300 scopus 로고    scopus 로고
    • Self-assembly of single-stranded RNA on carbon nanotube: Polyadenylic acid to form a duplex structure
    • DOI 10.1002/smll.200701054
    • Zhao, C., Peng, Y., Song, Y., Ren, J. & Qu, X. Self-assembly of single-stranded RNA on carbon nanotube: polyadenylic acid to form a duplex structure. Small 4, 656-661 (2008). (Pubitemid 351808065)
    • (2008) Small , vol.4 , Issue.5 , pp. 656-661
    • Zhao, C.1    Peng, Y.2    Song, Y.3    Ren, J.4    Qu, X.5
  • 14
    • 36849092925 scopus 로고    scopus 로고
    • Single-walled carbon nanotubes binding to human telomeric i-motif DNA: Significant acceleration of S1 nuclease cleavage rate
    • DOI 10.1039/b710950d
    • Peng, Y., Li, X., Ren, J. & Qu, X. Single-walled carbon nanotubes binding to human telomeric i-motif DNA: significant acceleration of S1 nuclease cleavage rate. Chem. Commun. 48, 5176-5178 (2007). (Pubitemid 350222795)
    • (2007) Chemical Communications , Issue.48 , pp. 5176-5178
    • Peng, Y.1    Li, X.2    Ren, J.3    Qu, X.4
  • 15
    • 70349747005 scopus 로고    scopus 로고
    • I-Motif quadruplex DNA-based biosensor for distinguishing single-and multi-walled carbon nanotubes
    • Peng, Y. et al. i-Motif quadruplex DNA-based biosensor for distinguishing single-and multi-walled carbon nanotubes. J. Am. Chem. Soc. 131, 13813-13818 (2009).
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 13813-13818
    • Peng, Y.1
  • 16
    • 59149086234 scopus 로고    scopus 로고
    • A DNA nanomachine induced by single-walled carbon nanotubes on gold surface
    • Zhao, C., Song, Y., Ren, J. & Qu, X. A DNA nanomachine induced by single-walled carbon nanotubes on gold surface. Biomaterials 30, 1739-1745 (2009).
    • (2009) Biomaterials , vol.30 , pp. 1739-1745
    • Zhao, C.1    Song, Y.2    Ren, J.3    Qu, X.4
  • 17
    • 53849130674 scopus 로고    scopus 로고
    • Single-walled carbon nanotubes binding to human telomeric i-Motif DNA under molecular-crowding conditions: More water molecules released
    • Zhao, C., Ren, J. & Qu, X. Single-walled carbon nanotubes binding to human telomeric i-Motif DNA under molecular-crowding conditions: more water molecules released. Chem. Eur. J. 14, 5435-5439 (2008).
    • (2008) Chem. Eur. J. , vol.14 , pp. 5435-5439
    • Zhao, C.1    Ren, J.2    Qu, X.3
  • 18
    • 68949164684 scopus 로고    scopus 로고
    • Knocking-down cyclin A(2) by siRNA suppresses apoptosis and switches differentiation pathways in K562 cells upon administration with doxorubicin
    • Wang, X., Song, Y., Ren, J. & Qu, X. Knocking-down cyclin A(2) by siRNA suppresses apoptosis and switches differentiation pathways in K562 cells upon administration with doxorubicin. PLoS One 4, e6665 (2009).
    • (2009) PLoS One , vol.4
    • Wang, X.1    Song, Y.2    Ren, J.3    Qu, X.4
  • 20
    • 0037096736 scopus 로고    scopus 로고
    • Detection of telomerase inhibitors based on G-quadruplex ligands by a modified telomeric repeat amplification protocol assay
    • Gomez, D., Mergny, J.L. & Riou, J.F. Detection of telomerase inhibitors based on G-quadruplex ligands by a modified telomeric repeat amplification protocol assay. Cancer Res. 62, 3365-3368 (2002). (Pubitemid 34651379)
    • (2002) Cancer Research , vol.62 , Issue.12 , pp. 3365-3368
    • Gomez, D.1    Mergny, J.-L.2    Riou, J.-F.3
  • 21
    • 11144235139 scopus 로고    scopus 로고
    • Processive utilization of the human telomerase template: Lack of a requirement for template switching
    • DOI 10.1074/jbc.M407768200
    • Rivera, M. A. & Blackburn, E. H. Processive utilization of the human telomerase template: lack of a requirement for template switching. J. Biol. Chem. 279, 53770-53781 (2004). (Pubitemid 40051886)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.51 , pp. 53770-53781
    • Rivera, M.A.1    Blackburn, E.H.2
  • 22
    • 80051762076 scopus 로고    scopus 로고
    • G-quadruplex formation at the 3′ end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase
    • Wang, Q. et al. G-quadruplex formation at the 3′ end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase. Nucleic Acids Res. 39, 6229-6237 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. 6229-6237
    • Wang, Q.1
  • 23
    • 33644865847 scopus 로고    scopus 로고
    • Extension of G-quadruplex DNA by ciliate telomerase
    • DOI 10.1038/sj.emboj.7601006, PII 7601006
    • Oganesian, L., Moon, I. K., Bryan, T. M. & Jarstfer, M. B. Extension of G-quadruplex DNA by ciliate telomerase. EMBO J. 25, 1148-1159 (2006). (Pubitemid 43372127)
    • (2006) EMBO Journal , vol.25 , Issue.5 , pp. 1148-1159
    • Oganesian, L.1    Moon, I.K.2    Bryan, T.M.3    Jarstfer, M.B.4
  • 26
    • 34247582332 scopus 로고    scopus 로고
    • SiRNA delivery into human T cells and primary cells with carbon-nanotube transporters
    • DOI 10.1002/anie.200604295
    • Liu, Z., Winters, M., Holodniy, M. & Dai, H. siRNA delivery into human T cells and primary cells with carbonnanotube transporters. Angew Chem. Int. Ed. 46, 2023-2027 (2007). (Pubitemid 46973660)
    • (2007) Angewandte Chemie - International Edition , vol.46 , Issue.12 , pp. 2023-2027
    • Liu, Z.1    Winters, M.2    Holodniy, M.3    Dai, H.4
  • 27
    • 56849127859 scopus 로고    scopus 로고
    • Reversible accumulation of PEGylated single-walled carbon nanotubes in the mammalian nucleus
    • Cheng, J. et al. Reversible accumulation of PEGylated single-walled carbon nanotubes in the mammalian nucleus. ACS Nano 2, 2085-2094 (2008).
    • (2008) ACS Nano , vol.2 , pp. 2085-2094
    • Cheng, J.1
  • 28
    • 55249084450 scopus 로고    scopus 로고
    • Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA
    • Yu, H., Ren, J. & Qu, X. Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA. Nucleic Acids Res. 36, 5695-5703 (2008).
    • (2008) Nucleic Acids Res. , vol.36 , pp. 5695-5703
    • Yu, H.1    Ren, J.2    Qu, X.3
  • 29
    • 33745374520 scopus 로고    scopus 로고
    • Hydration regulates thermodynamics of G-quadruplex formation under molecular crowding conditions
    • DOI 10.1021/ja061267m
    • Miyoshi, D., Karimata, H. & Sugimoto, N. Hydration regulates thermodynamics of G-quadruplex formation under molecular crowding conditions. J. Am. Chem. Soc. 128, 7957-7963 (2010). (Pubitemid 43945737)
    • (2006) Journal of the American Chemical Society , vol.128 , Issue.24 , pp. 7957-7963
    • Miyoshi, D.1    Karimata, H.2    Sugimoto, N.3
  • 30
    • 74849106906 scopus 로고    scopus 로고
    • DNA Loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivity
    • Yu, H. et al. DNA Loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivity. J. Med. Chem. 53, 492-498 (2010).
    • (2010) J. Med. Chem. , vol.53 , pp. 492-498
    • Yu, H.1
  • 32
    • 77949666221 scopus 로고    scopus 로고
    • Label-free colorimetric detection of single nucleotide polymorphism by using single-walled carbon nanotube intrinsic peroxidase-like activity
    • Song, Y. et al. Label-free colorimetric detection of single nucleotide polymorphism by using single-walled carbon nanotube intrinsic peroxidase-like activity. Chem. Eur. J. 16, 3617-3621 (2010).
    • (2010) Chem. Eur. J. , vol.16 , pp. 3617-3621
    • Song, Y.1
  • 33
    • 0032578525 scopus 로고    scopus 로고
    • Inhibition of human telomerase by 2′-O-methyl-RNA
    • Pitts, A. E. & Corey, D. R. Inhibition of human telomerase by 2′-O-methyl-RNA. Proc. Natl Acad. Sci. USA 95, 11549-11554 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11549-11554
    • Pitts, A.E.1    Corey, D.R.2
  • 34
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • DOI 10.1016/S0092-8674(00)80932-0
    • van Steensel, B., Smogorzewska, A. & de Lange, T. TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413 (1998). (Pubitemid 28093017)
    • (1998) Cell , vol.92 , Issue.3 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 35
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • DOI 10.1016/S0960-9822(03)00542-6
    • Takai, H., Smogorzewska, A. & de Lange, T. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 1549-1556 (2003). (Pubitemid 37078413)
    • (2003) Current Biology , vol.13 , Issue.17 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    De Lange, T.3
  • 36
    • 20144369806 scopus 로고    scopus 로고
    • Highly prevalent putative quadruplex sequence motifs in human DNA
    • DOI 10.1093/nar/gki553
    • Todd, A. K., Johnston, M. & Neidle, S. Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res. 33, 2901-2907 (2005). (Pubitemid 41511229)
    • (2005) Nucleic Acids Research , vol.33 , Issue.9 , pp. 2901-2907
    • Todd, A.K.1    Johnston, M.2    Neidle, S.3
  • 38
    • 33645280314 scopus 로고    scopus 로고
    • G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells
    • Tahara, H. et al. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells. Oncogene 25, 1955-1966 (2006).
    • (2006) Oncogene , vol.25 , pp. 1955-1966
    • Tahara, H.1
  • 40
    • 70349921098 scopus 로고    scopus 로고
    • Induction of aneuploidy by single-walled carbon nanotubes
    • Sargent, L. M. et al. Induction of aneuploidy by single-walled carbon nanotubes. Environ. Mol. Mutagen. 50, 708-717 (2009).
    • (2009) Environ. Mol. Mutagen. , vol.50 , pp. 708-717
    • Sargent, L.M.1
  • 41
    • 27944496124 scopus 로고    scopus 로고
    • Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
    • DOI 10.1016/j.molcel.2005.09.024, PII S109727650501645X
    • Verdun, R. E., Crabbe, L., Haggblom, C. & Karlseder, J. Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol. Cell 20, 551-561 (2005). (Pubitemid 41668640)
    • (2005) Molecular Cell , vol.20 , Issue.4 , pp. 551-561
    • Verdun, R.E.1    Crabbe, L.2    Haggblom, C.3    Karlseder, J.4
  • 43
    • 34250319300 scopus 로고    scopus 로고
    • Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6A resolution
    • DOI 10.1093/nar/gkm139
    • Fenn, S. et al. Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6A resolution. Nucleic Acids Res. 3, 2651-2660 (2007). (Pubitemid 47073678)
    • (2007) Nucleic Acids Research , vol.35 , Issue.8 , pp. 2651-2660
    • Fenn, S.1    Du, Z.2    Lee, J.K.3    Tjhen, R.4    Stroud, R.M.5    James, T.L.6
  • 44
    • 28544453509 scopus 로고    scopus 로고
    • G-tail telomere HPA: Simple measurement of human single-stranded telomeric overhangs
    • DOI 10.1038/nmeth797, PII N797
    • Tahara, H., Kusunoki, M., Yamanaka, Y., Matsumura, S. & Ide, T. G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangs. Nat. Methods 2, 829-831 (2005). (Pubitemid 41741532)
    • (2005) Nature Methods , vol.2 , Issue.11 , pp. 829-831
    • Tahara, H.1    Kusunoki, M.2    Yamanaka, Y.3    Matsumura, S.4    Ide, T.5
  • 45
    • 0041353443 scopus 로고    scopus 로고
    • Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: Involvement of ATM-dependent DNA damage response pathways
    • DOI 10.1038/sj.onc.1206833
    • Tauchi, T. et al. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways. Oncogene 22, 5338-5347 (2003). (Pubitemid 37056096)
    • (2003) Oncogene , vol.22 , Issue.34 , pp. 5338-5347
    • Tauchi, T.1    Shin-Ya, K.2    Sashida, G.3    Sumi, M.4    Nakajima, A.5    Shimamoto, T.6    Ohyashiki, J.H.7    Ohyashiki, K.8
  • 46
    • 65649089445 scopus 로고    scopus 로고
    • The importance of negative superhelicity in inducing the formation of G-quadruplex and i-Motif structures in the c-Myc promoter: Sun, D. & Hurley, L. H. The importance of negative superhelicity in inducing the formation of G-quadruplex and i-Motif structures in the c-Myc promoter: Implications for drug targeting and control of gene expression
    • implications for drug targeting and control of gene expression. J. Med. Chem. 52, 2863-2874 (2009).
    • (2009) J. Med. Chem. , vol.52 , pp. 2863-2874
    • Sun, D.1    Hurley, L.H.2
  • 47
    • 79952344184 scopus 로고    scopus 로고
    • Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene
    • Sun, D., Guo, K. & Shin, Y. J. Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene. Nucleic Acids Res. 39, 1256-1265 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1256-1265
    • Sun, D.1    Guo, K.2    Shin, Y.J.3
  • 49
  • 50
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • DOI 10.1146/annurev.biochem.73.071403.160049
    • Smogorzewska, A. & de Lange, T. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73, 177-208 (2004). (Pubitemid 39050367)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 51
    • 68249156463 scopus 로고    scopus 로고
    • Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands
    • Palumbo, S. L., Ebbinghaus, S. W. & Hurley, L. H. Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands. J. Am. Chem. Soc. 131, 10878-10891 (2009).
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 10878-10891
    • Palumbo, S.L.1    Ebbinghaus, S.W.2    Hurley, L.H.3
  • 52
    • 0035476710 scopus 로고    scopus 로고
    • T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang
    • DOI 10.1093/emboj/20.19.5532
    • Stansel, R. M., de Lange, T. & Griffith, J. D. T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang. EMBO J. 20, 5532-5540 (2001). (Pubitemid 32959473)
    • (2001) EMBO Journal , vol.20 , Issue.19 , pp. 5532-5540
    • Stansel, R.M.1    De Lange, T.2    Griffith, J.D.3
  • 53
    • 11144223025 scopus 로고    scopus 로고
    • Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities
    • DOI 10.1110/ps.04983705
    • Hanaoka, S., Nagadoi, A. & Nishimura, Y. Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities. Protein Sci. 14, 119-130 (2005). (Pubitemid 40054123)
    • (2005) Protein Science , vol.14 , Issue.1 , pp. 119-130
    • Hanaoka, S.1    Nagadoi, A.2    Nishimura, Y.3
  • 54
    • 77955110561 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles
    • Chaudhury, A., Chander, P. & Howe, P. H. Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: focus on hnRNP E1's multifunctional regulatory roles. RNA 16, 1449-1462 (2010).
    • (2010) RNA , vol.16 , pp. 1449-1462
    • Chaudhury, A.1    Chander, P.2    Howe, P.H.3
  • 55
    • 81755172447 scopus 로고    scopus 로고
    • Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex
    • Brown, R. V., Danford, F. L., Gokhale, V., Hurley, L. H. & Brooks, T. A. Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex. J. Biol. Chem. 286, 41018-41027 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 41018-41027
    • Brown, R.V.1    Danford, F.L.2    Gokhale, V.3    Hurley, L.H.4    Brooks, T.A.5
  • 57
    • 24044481977 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: Implications for replication of telomeric DNA
    • DOI 10.1093/nar/gki777
    • Ghosal, G. & Muniyappa, K. Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA. Nucleic Acids Res. 33, 4692-4703 (2005). (Pubitemid 41418871)
    • (2005) Nucleic Acids Research , vol.33 , Issue.15 , pp. 4692-4703
    • Ghosal, G.1    Muniyappa, K.2
  • 58
    • 40649085753 scopus 로고    scopus 로고
    • Telomeric 3′-overhang length is associated with the size of telomeres
    • Rahman, R., Forsyth, N. R. & Cui, W. Telomeric 3′-overhang length is associated with the size of telomeres. Exp. Gerontol. 43, 258-265 (2008).
    • (2008) Exp. Gerontol. , vol.43 , pp. 258-265
    • Rahman, R.1    Forsyth, N.R.2    Cui, W.3
  • 59
    • 0034733606 scopus 로고    scopus 로고
    • Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang
    • DOI 10.1074/jbc.M002843200
    • Huffman, K. E., Levene, S. D., Tesmer, V. M., Shay, J. W. & Wright, W. E. Telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang. J. Biol. Chem. 275, 19719-19722 (2000). (Pubitemid 30441569)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.26 , pp. 19719-19722
    • Huffman, K.E.1    Levene, S.D.2    Tesmer, V.M.3    Shay, J.W.4    Wright, W.E.5


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