Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways

Anticancer Research

Volumn 32, Issue 9, 2012, Pages 3643-3649

  Miwa, Shinji ^a   Sugimoto, Naotoshi ^a   Yamamoto, Norio ^a   Shirai, Toshiharu ^a   Nishida, Hideji ^a   Hayashi, Katsuhiro ^a   Kimura, Hiroaki ^a   Takeuchi, Akihiko ^a   Igarashi, Kentaro ^a   Yachie, Akihiro ^a   Tsuchiya, Hiroyuki ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Caffeine; ERK; mTOR; NF B; Osteosarcoma; p70S6K

Indexed keywords

CAFFEINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN KINASE B; RAPAMYCIN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOSARCOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

APOPTOSIS; BONE NEOPLASMS; CAFFEINE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; OSTEOSARCOMA; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84866999366     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

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