메뉴 건너뛰기




Volumn 18, Issue 19-20, 2012, Pages 2114-2124

Improved chondrogenesis and engineered cartilage formation from TGF-β3-expressing adipose-derived stem cells cultured in the rotating-shaft bioreactor

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIALS; BIOREACTORS; GENE TRANSFER; HISTOLOGY; MONOLAYERS; STEM CELLS; TISSUE;

EID: 84866979497     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0010     Document Type: Article
Times cited : (40)

References (48)
  • 1
    • 80052965339 scopus 로고    scopus 로고
    • Recent progress in cartilage tissue engineering
    • Keeney, M., Lai, J.H., and Yang, F. Recent progress in cartilage tissue engineering. Curr Opin Biotechnol 25, 734, 2011.
    • (2011) Curr Opin Biotechnol , vol.25 , pp. 734
    • Keeney, M.1    Lai, J.H.2    Yang, F.3
  • 2
    • 1642563967 scopus 로고    scopus 로고
    • The role of bioreac-tors in tissue engineering
    • Martin, I., Wendt, D., and Heberer, M. The role of bioreac-tors in tissue engineering. Trends Biotechnol 22, 80, 2004.
    • (2004) Trends Biotechnol , vol.22 , pp. 80
    • Martin, I.1    Wendt, D.2    Heberer, M.3
  • 3
    • 10044290683 scopus 로고    scopus 로고
    • A novel rotating-shaft bioreactor for two-phase cultivation of tissue-engineered cartilage
    • Chen, H.-C., Lee, H.-P., Sung, M.-L., Liao, C.-J., and Hu, Y.-C. A novel rotating-shaft bioreactor for two-phase cultivation of tissue-engineered cartilage. Biotechnol Prog 20, 1802, 2004.
    • (2004) Biotechnol Prog , vol.20 , pp. 1802
    • Chen, H.-C.1    Lee, H.-P.2    Sung, M.-L.3    Liao, C.-J.4    Hu, Y.-C.5
  • 5
    • 33646367147 scopus 로고    scopus 로고
    • Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6
    • Estes, B.T., Wu, A.W., and Guilak, F. Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6. Arthritis Rheum 54, 1222, 2006.
    • (2006) Arthritis Rheum , vol.54 , pp. 1222
    • Estes, B.T.1    Wu, A.W.2    Guilak, F.3
  • 6
    • 73449101414 scopus 로고    scopus 로고
    • Cartilage regeneration using adipose-derived stem cells and the controlled-released hybrid microspheres
    • Han, Y., Wei, Y., Wang, S., and Song, Y. Cartilage regeneration using adipose-derived stem cells and the controlled-released hybrid microspheres. Joint Bone Spine 77, 27, 2010.
    • (2010) Joint Bone Spine , vol.77 , pp. 27
    • Han, Y.1    Wei, Y.2    Wang, S.3    Song, Y.4
  • 8
    • 33646190866 scopus 로고    scopus 로고
    • Ex vivo gene therapy approaches to cartilage repair
    • Gelse, K., and Schneider, H. Ex vivo gene therapy approaches to cartilage repair. Adv Drug Deliv Rev 58, 259, 2006.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 259
    • Gelse, K.1    Schneider, H.2
  • 9
    • 77952012256 scopus 로고    scopus 로고
    • Mesenchymal stem cells expressing osteo-genic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect
    • Kumar, S., Wan, C., Ramaswamy, G., Clemens, T.L., and Ponnazhagan, S. Mesenchymal stem cells expressing osteo-genic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect. Mol Ther 18, 1026, 2010.
    • (2010) Mol Ther , vol.18 , pp. 1026
    • Kumar, S.1    Wan, C.2    Ramaswamy, G.3    Clemens, T.L.4    Ponnazhagan, S.5
  • 11
    • 77953811664 scopus 로고    scopus 로고
    • In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes
    • Wang, W., Li, B., Li, Y.L., Jiang, Y.Z., Ouyang, H.W., and Gao, C.Y. In vivo restoration of full-thickness cartilage defects by poly(lactide-co- glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes. Biomaterials 31, 5953, 2010.
    • (2010) Biomaterials , vol.31 , pp. 5953
    • Wang, W.1    Li, B.2    Li, Y.L.3    Jiang, Y.Z.4    Ouyang, H.W.5    Gao, C.Y.6
  • 12
    • 34248181957 scopus 로고    scopus 로고
    • Adeno-associated viral gene transfer of transforming growth factor-b1 to human mesenchymal stem cells improves cartilage repair
    • Pagnotto, M.R., Wang, Z., Karpie, J.C., Ferretti, M., Xiao, X., and Chu, C.R. Adeno-associated viral gene transfer of transforming growth factor-b1 to human mesenchymal stem cells improves cartilage repair. Gene Ther 14, 804, 2007.
    • (2007) Gene Ther , vol.14 , pp. 804
    • Pagnotto, M.R.1    Wang, Z.2    Karpie, J.C.3    Ferretti, M.4    Xiao, X.5    Chu, C.R.6
  • 13
    • 77950687027 scopus 로고    scopus 로고
    • The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors
    • Diekman, B.O., Estes, B.T., and Guilak, F. The effects of BMP6 overexpression on adipose stem cell chondrogenesis: interactions with dexamethasone and exogenous growth factors. J Biomed Mater Res A 93, 994, 2010.
    • (2010) J Biomed Mater Res A , vol.93 , pp. 994
    • Diekman, B.O.1    Estes, B.T.2    Guilak, F.3
  • 14
    • 34147186789 scopus 로고    scopus 로고
    • Ectopic neocartilage formation from pre-differentiated human adipose derived stem cells induced by adenoviral-mediated transfer of hTGF beta2
    • Jin, X.B., Sun, Y.S., Zhang, K., Wang, J., Shi, T.P., Ju, X.D., and Lou, S.Q. Ectopic neocartilage formation from pre-differentiated human adipose derived stem cells induced by adenoviral-mediated transfer of hTGF beta2. Biomaterials 28, 2994, 2007.
    • (2007) Biomaterials , vol.28 , pp. 2994
    • Jin, X.B.1    Sun, Y.S.2    Zhang, K.3    Wang, J.4    Shi, T.P.5    Ju, X.D.6    Lou, S.Q.7
  • 15
    • 80053453533 scopus 로고    scopus 로고
    • Baculo-virus as a gene delivery vector: Recent understandings of molecular alterations in transduced cells and latest applications
    • Chen, C.-Y., Lin, C.-Y., Chen, G.-Y., and Hu, Y.-C. Baculo-virus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications. Biotechnol Adv 29, 618, 2011.
    • (2011) Biotechnol Adv , vol.29 , pp. 618
    • Chen, C.-Y.1    Lin, C.-Y.2    Chen, G.-Y.3    Hu, Y.-C.4
  • 17
    • 66249115629 scopus 로고    scopus 로고
    • Baculovirus-mediated growth factor expression in dedifferentiated chondrocytes accelerates redifferentiation: Effects of combinational transduction
    • Sung, L.-Y., Chiu, H.-Y., Chen, H.-C., Chen, Y.-L., Chuang, C.-K., and Hu, Y.-C. Baculovirus-mediated growth factor expression in dedifferentiated chondrocytes accelerates redifferentiation: effects of combinational transduction. Tissue Eng Part A 15, 1353, 2009.
    • (2009) Tissue Eng Part A , vol.15 , pp. 1353
    • Sung, L.-Y.1    Chiu, H.-Y.2    Chen, H.-C.3    Chen, Y.-L.4    Chuang, C.-K.5    Hu, Y.-C.6
  • 18
    • 38949133043 scopus 로고    scopus 로고
    • Combination of baculovirus-mediated BMP-2 expression and rotating-shaft bioreactor culture synergistically enhances cartilage formation
    • Chen, H.-C., Sung, L.-Y., Lo, W.-H., Chuang, C.-K., Wang, Y.-H., Lin, J.-L., and Hu, Y.-C. Combination of baculovirus-mediated BMP-2 expression and rotating-shaft bioreactor culture synergistically enhances cartilage formation. Gene Ther 15, 309, 2008.
    • (2008) Gene Ther , vol.15 , pp. 309
    • Chen, H.-C.1    Sung, L.-Y.2    Lo, W.-H.3    Chuang, C.-K.4    Wang, Y.-H.5    Lin, J.-L.6    Hu, Y.-C.7
  • 19
    • 56449083886 scopus 로고    scopus 로고
    • The repair of osteochon-dral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture
    • Chen, H.-C., Chang, Y.-H., Chuang, C.-K., Lin, C.-Y., Sung, L.-Y., Wang, Y.-H., and Hu, Y.-C. The repair of osteochon-dral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture. Biomaterials 30, 674, 2009.
    • (2009) Biomaterials , vol.30 , pp. 674
    • Chen, H.-C.1    Chang, Y.-H.2    Chuang, C.-K.3    Lin, C.-Y.4    Sung, L.-Y.5    Wang, Y.-H.6    Hu, Y.-C.7
  • 20
    • 63949083132 scopus 로고    scopus 로고
    • Development of a hybrid baculoviral vector for sustained transgene expression
    • Lo, W.-H., Hwang, S.-M., Chuang, C.-K., Chen, C.-Y., and Hu, Y.-C. Development of a hybrid baculoviral vector for sustained transgene expression. Mol Ther 17, 658, 2009.
    • (2009) Mol Ther , vol.17 , pp. 658
    • Lo, W.-H.1    Hwang, S.-M.2    Chuang, C.-K.3    Chen, C.-Y.4    Hu, Y.-C.5
  • 21
    • 76749091376 scopus 로고    scopus 로고
    • The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells
    • Lin, C.-Y., Chang, Y.-H., Lin, K.-J., Yen, T.-Z., Tai, C.-L., Chen, C.-Y., Lo, W.-H., Hsiao, I.-T., and Hu, Y.-C. The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells. Biomaterials 31, 3222, 2010.
    • (2010) Biomaterials , vol.31 , pp. 3222
    • Lin, C.-Y.1    Chang, Y.-H.2    Lin, K.-J.3    Yen, T.-Z.4    Tai, C.-L.5    Chen, C.-Y.6    Lo, W.-H.7    Hsiao, I.-T.8    Hu, Y.-C.9
  • 22
    • 79960096418 scopus 로고    scopus 로고
    • The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects
    • Lin, C.-Y., Lin, K.-J., Kao, C.-Y., Chen, M.-C., Yen, T.-Z., Lo, W.-H., Chang, Y.-H., and Hu, Y.-C. The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects. Biomaterials 32, 6505, 2011.
    • (2011) Biomaterials , vol.32 , pp. 6505
    • Lin, C.-Y.1    Lin, K.-J.2    Kao, C.-Y.3    Chen, M.-C.4    Yen, T.-Z.5    Lo, W.-H.6    Chang, Y.-H.7    Hu, Y.-C.8
  • 24
    • 0035882056 scopus 로고    scopus 로고
    • Chon-drogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
    • Barry, F., Boynton, R.E., Liu, B., and Murphy, J.M. Chon-drogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components. Exp Cell Res 268, 189, 2001.
    • (2001) Exp Cell Res , vol.268 , pp. 189
    • Barry, F.1    Boynton, R.E.2    Liu, B.3    Murphy, J.M.4
  • 27
    • 77956788659 scopus 로고    scopus 로고
    • The response of bone marrow-derived mesenchymal stem cells to dynamic compression following TGF-beta3 induced chondrogenic differentiation
    • Thorpe, S.D., Buckley, C.T., Vinardell, T., O'Brien, F.J., Campbell, V.A., and Kelly, D.J. The response of bone marrow-derived mesenchymal stem cells to dynamic compression following TGF-beta3 induced chondrogenic differentiation. Ann Biomed Eng 38, 2896, 2010.
    • (2010) Ann Biomed Eng , vol.38 , pp. 2896
    • Thorpe, S.D.1    Buckley, C.T.2    Vinardell, T.3    O'Brien, F.J.4    Campbell, V.A.5    Kelly, D.J.6
  • 29
    • 70349952050 scopus 로고    scopus 로고
    • Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering
    • Rada, T., Reis, R.L., and Gomes, M.E. Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering. Tissue Eng Part B 15, 113, 2009.
    • (2009) Tissue Eng Part B , vol.15 , pp. 113
    • Rada, T.1    Reis, R.L.2    Gomes, M.E.3
  • 30
    • 34247587579 scopus 로고    scopus 로고
    • Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6
    • Hennig, T., Lorenz, H., Thiel, A., Goetzke, K., Dickhut, A., Geiger, F., and Richter, W. Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6. J Cell Physiol 211, 682, 2007.
    • (2007) J Cell Physiol , vol.211 , pp. 682
    • Hennig, T.1    Lorenz, H.2    Thiel, A.3    Goetzke, K.4    Dickhut, A.5    Geiger, F.6    Richter, W.7
  • 31
    • 77649271173 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human adipose-derived stem cells in polyglycolic acid mesh scaffolds under dynamic culture conditions
    • Mahmoudifar, N., and Doran, P.M. Chondrogenic differentiation of human adipose-derived stem cells in polyglycolic acid mesh scaffolds under dynamic culture conditions. Biomaterials 31, 3858, 2010.
    • (2010) Biomaterials , vol.31 , pp. 3858
    • Mahmoudifar, N.1    Doran, P.M.2
  • 32
    • 77956430523 scopus 로고    scopus 로고
    • Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression
    • Meyer, E.G., Buckley, C.T., Thorpe, S.D., and Kelly, D.J. Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression. J Biomech 43, 2516, 2010.
    • (2010) J Biomech , vol.43 , pp. 2516
    • Meyer, E.G.1    Buckley, C.T.2    Thorpe, S.D.3    Kelly, D.J.4
  • 35
    • 61549118493 scopus 로고    scopus 로고
    • Repair of articular cartilage defect in non-weight bearing areas using adipose derived stem cells loaded polyglycolic acid mesh
    • Cui, L., Wu, Y., Cen, L., Zhou, H., Yin, S., Liu, G., Liu, W., and Cao, Y. Repair of articular cartilage defect in non-weight bearing areas using adipose derived stem cells loaded polyglycolic acid mesh. Biomaterials 30, 2683, 2009.
    • (2009) Biomaterials , vol.30 , pp. 2683
    • Cui, L.1    Wu, Y.2    Cen, L.3    Zhou, H.4    Yin, S.5    Liu, G.6    Liu, W.7    Cao, Y.8
  • 36
    • 34247466934 scopus 로고    scopus 로고
    • A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors
    • Afizah, H., Yang, Z., Hui, J.H., Ouyang, H.W., and Lee, E.H. A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors. Tissue Eng 13, 659, 2007.
    • (2007) Tissue Eng , vol.13 , pp. 659
    • Afizah, H.1    Yang, Z.2    Hui, J.H.3    Ouyang, H.W.4    Lee, E.H.5
  • 37
    • 26444553353 scopus 로고    scopus 로고
    • Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?
    • Im, G.I., Shin, Y.W., and Lee, K.B. Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells? Os-teoarthritis Cartilage 13, 845, 2005.
    • (2005) Os-teoarthritis Cartilage , vol.13 , pp. 845
    • Im, G.I.1    Shin, Y.W.2    Lee, K.B.3
  • 38
    • 65249090766 scopus 로고    scopus 로고
    • Chondrogenic differentiation of adipose tissue-derived mesenchymal stem cells: Greater doses of growth factor are necessary
    • Kim, H.-J., and Im, G.-I. Chondrogenic differentiation of adipose tissue-derived mesenchymal stem cells: Greater doses of growth factor are necessary. J Orthop Res 27, 612, 2009.
    • (2009) J Orthop Res , vol.27 , pp. 612
    • Kim, H.-J.1    Im, G.-I.2
  • 39
    • 79951708094 scopus 로고    scopus 로고
    • Adipose tissue-derived stem cells show both immunogenic and immunosuppressive properties after chondrogenic differentiation
    • Technau, A., Froelich, K., Hagen, R., and Kleinsasser, N. Adipose tissue-derived stem cells show both immunogenic and immunosuppressive properties after chondrogenic differentiation. Cytotherapy 13, 310, 2011.
    • (2011) Cytotherapy , vol.13 , pp. 310
    • Technau, A.1    Froelich, K.2    Hagen, R.3    Kleinsasser, N.4
  • 40
    • 72649099116 scopus 로고    scopus 로고
    • Transient exposure to transforming growth factor beta 3 improves the mechanical properties of mesenchymal stem cellladen cartilage constructs in a density-dependent manner
    • Huang, A.H., Stein, A., Tuan, R.S., and Mauck, R.L. Transient exposure to transforming growth factor beta 3 improves the mechanical properties of mesenchymal stem cellladen cartilage constructs in a density-dependent manner. Tissue Eng Part A 15, 3461, 2009.
    • (2009) Tissue Eng Part A , vol.15 , pp. 3461
    • Huang, A.H.1    Stein, A.2    Tuan, R.S.3    Mauck, R.L.4
  • 41
    • 77955071183 scopus 로고    scopus 로고
    • Comparative review of growth factors for induction of three-dimensional in vitro chondrogenesis in human mesenchymal stem cells isolated from bone marrow and adipose tissue
    • Puetzer, J.L., Petitte, J.N., and Loboa, E.G. Comparative review of growth factors for induction of three-dimensional in vitro chondrogenesis in human mesenchymal stem cells isolated from bone marrow and adipose tissue. Tissue Eng Part B 16, 435, 2010.
    • (2010) Tissue Eng Part B , vol.16 , pp. 435
    • Puetzer, J.L.1    Petitte, J.N.2    Loboa, E.G.3
  • 43
    • 80455164787 scopus 로고    scopus 로고
    • Construction of eukaryotic expression plasmid of hTGF-b3 and its inducing effect on differentiation of precartilaginous stem cells into chondroblasts
    • You, H., Chen, A., Liu, T., Wang, M., and Zhang, G. Construction of eukaryotic expression plasmid of hTGF-b3 and its inducing effect on differentiation of precartilaginous stem cells into chondroblasts. J Huazhong Univ Sci Technolog Med Sci 31, 524, 2011.
    • (2011) J Huazhong Univ Sci Technolog Med Sci , vol.31 , pp. 524
    • You, H.1    Chen, A.2    Liu, T.3    Wang, M.4    Zhang, G.5
  • 44
    • 71649102759 scopus 로고    scopus 로고
    • A study on the effect of degradation media on the physical and mechanical properties of porous PLGA 85/15 scaffolds
    • Perron, J.K., Naguib, H.E., Daka, J., Chawla, A., and Wilkins, R. A study on the effect of degradation media on the physical and mechanical properties of porous PLGA 85/15 scaffolds. J Biomed Mater Res B Appl Biomater 91, 876, 2009.
    • (2009) J Biomed Mater Res B Appl Biomater , vol.91 , pp. 876
    • Perron, J.K.1    Naguib, H.E.2    Daka, J.3    Chawla, A.4    Wilkins, R.5
  • 45
    • 77953491512 scopus 로고    scopus 로고
    • Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma
    • Savaraj, N., You, M., Wu, C., Wangpaichitr, M., Kuo, M.T., and Feun, L.G. Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma. Curr Mol Med 10, 405, 2010.
    • (2010) Curr Mol Med , vol.10 , pp. 405
    • Savaraj, N.1    You, M.2    Wu, C.3    Wangpaichitr, M.4    Kuo, M.T.5    Feun, L.G.6
  • 46
    • 67349276428 scopus 로고    scopus 로고
    • Bacu-lovirus transduction of mesenchymal stem cells: In vitro responses and in vivo immune responses after cell transplantation
    • Chuang, C.-K., Wong, T.-H., Hwang, S.-M., Chang, Y.-H., Chen, Y.-H., Chiu, Y.-C., Huang, S.-F., and Hu, Y.-C. Bacu-lovirus transduction of mesenchymal stem cells: In vitro responses and in vivo immune responses after cell transplantation. Mol Ther 17, 889, 2009.
    • (2009) Mol Ther , vol.17 , pp. 889
    • Chuang, C.-K.1    Wong, T.-H.2    Hwang, S.-M.3    Chang, Y.-H.4    Chen, Y.-H.5    Chiu, Y.-C.6    Huang, S.-F.7    Hu, Y.-C.8
  • 47
    • 69949162433 scopus 로고    scopus 로고
    • High-efficiency transient transduction of human embryonic stem cell-derived neurons with baculoviral vectors
    • Zeng, J.-M., Du, J., Lin, J.-K., Bak, X.-Y., Wu, C.-X., and Wang, S. High-efficiency transient transduction of human embryonic stem cell-derived neurons with baculoviral vectors. Mol Ther 17, 1585, 2009.
    • (2009) Mol Ther , vol.17 , pp. 1585
    • Zeng, J.-M.1    Du, J.2    Lin, J.-K.3    Bak, X.-Y.4    Wu, C.-X.5    Wang, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.