The role of XRCC6 T-991C functional polymorphism in renal cell carcinoma

Anticancer Research

Volumn 32, Issue 9, 2012, Pages 3855-3860

  Chang, Wen Shin ^a,b   Ke, Hung Lung ^c,d   Tsai, Chia Wen ^a,b   Lien, Chi Shun ^b   Liao, Wen Ling ^b   Lin, Hui Hui ^c,d   Lee, Meng Hsuan ^a,b   Wu, Hsi Chin ^b   Chang, Chao Hsiang ^b   Chen, Chi Cheng ^b   Lee, Hong Zin ^a,b   Bau, Da Tian ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

DNA repair; Ku70; Non homologous end joining; Polymorphism; Renal cell carcinoma; T 991C; XRCC6

Indexed keywords

MESSENGER RNA; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; XRCC6 PROTEIN;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN TISSUE; INTRON; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANTIGENS, NUCLEAR; CARCINOMA, RENAL CELL; CASE-CONTROL STUDIES; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER;

EID: 84866978374     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Lipworth L, Tarone RE and McLaughlin JK: The epidemiology of renal cell carcinoma. J Urol 176: 2353-2358, 2006. (Pubitemid 44665976)
2. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ and Thun MJ: Cancer statistics, 2005. CA Cancer J Clin 55: 10-30, 2005. (Pubitemid 40310185)
3. Murai M and Oya M: Renal cell carcinoma: Etiology, incidence and epidemiology. Curr Opin Urol 14: 229-233, 2004. (Pubitemid 38932351)
4. Lindblad P: Epidemiology of renal cell carcinoma. Scand J Surg 93: 88-96, 2004.
5. Sugimura T, Kumimoto H, Tohnai I, Fukui T, Matsuo K, Tsurusako S, Mitsudo K, Ueda M, Tajima K and Ishizaki K: Gene-environment interaction involved in oral carcinogenesis: Molecular epidemiological study for metabolic and DNA repair gene polymorphisms. J Oral Pathol Med 35: 11-18, 2006.
6. Vogelstein B, Alberts B and Shine K: Genetics. Please don't call it cloning! Science 295: 1237, 2002. (Pubitemid 34157602)
7. Miller KL, Karagas MR, Kraft P, Hunter DJ, Catalano PJ, Byler SH and Nelson HH: XPA, haplotypes, and risk of basal and squamous cell carcinoma. Carcinogenesis 27: 1670-1675, 2006. (Pubitemid 44288056)
8. Wood RD, Mitchell M, Sgouros J and Lindahl T: Human DNA repair genes. Science 291: 1284-1289, 2001. (Pubitemid 32173086)
9. Khanna KK and Jackson SP: DNA double-strand breaks: Signaling, repair and the cancer connection. Nat Genet 27: 247-254, 2001. (Pubitemid 32201842)
10. Jackson SP: Sensing and repairing DNA double-strand breaks. Carcinogenesis 23: 687-696, 2002.
11. Han J, Colditz GA, Samson LD and Hunter DJ: Polymorphisms in DNA double-strand break repair genes and skin cancer risk. Cancer Res 64: 3009-3013, 2004. (Pubitemid 38581398)
12. Willems P, Claes K, Baeyens A, Vandersickel V, Werbrouck J, De Ruyck K, Poppe B, Van den Broecke R, Makar A, Marras E, Perletti G, Thierens H and Vral A: Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity. Genes Chromosomes Cancer 47: 137-148, 2008.
13. Bau DT, Mau YC, Ding SL, Wu PE and Shen CY: DNA double-strand break repair capacity and risk of breast cancer. Carcinogenesis 28: 1726-1730, 2007.
14. Bau DT, Fu YP, Chen ST, Cheng TC, Yu JC, Wu PE and Shen CY: Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1 . Cancer Res 64: 5013-5019, 2004.
15. Chiu CF, Wang CH, Wang CL, Lin CC, Hsu NY, Weng JR and Bau DT: A novel single nucleotide polymorphism in XRCC4 gene is associated with gastric cancer susceptibility in Taiwan. Ann Surg Oncol 15: 514-518, 2008.
16. Wang SY, Peng L, Li CP, Li AP, Zhou JW, Zhang ZD and Liu QZ: Genetic variants of the XRCC7 gene involved in DNA repair and risk of human bladder cancer. Int J Urol 15: 534-539, 2008. (Pubitemid 351713194)
17. Chiu CF, Tsai MH, Tseng HC, Wang CL, Wang CH, Wu CN, Lin CC and Bau DT: A novel single nucleotide polymorphism in XRCC4 gene is associated with oral cancer susceptibility in Taiwanese patients. Oral Oncol 44: 898-902, 2008.
18. Hirata H, Hinoda Y, Matsuyama H, Tanaka Y, Okayama N, Suehiro Y, Zhao H, Urakami S, Kawamoto K, Kawakami T, Igawa M, Naito K and Dahiya R: Polymorphisms of DNA repair genes are associated with renal cell carcinoma. Biochem Biophys Res Commun 342: 1058-1062, 2006.
19. Yang MD, Wang HC, Chang WS, Tsai CW and Bau DT: Genetic polymorphisms of DNA double strand break gene Ku70 and gastric cancer in Taiwan. BMC Cancer 11: 174, 2011.
20. Fu YP, Yu JC, Cheng TC, Lou MA, Hsu GC, Wu CY, Chen ST, Wu HS, Wu PE and Shen CY: Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: A multigenic study on cancer susceptibility. Cancer Res 63: 2440-2446, 2003. (Pubitemid 36605181)
21. Yang MD, Hsu YM, Kuo YS, Chen HS, Chang CL, Wu CN, Chang CH, Liao YM, Wang HC, Wang MF and Bau DT: Significant association of Ku80 single nucleotide polymorphisms with colorectal cancer susceptibility in Central Taiwan. Anticancer Res 29: 2239-2242, 2009.
22. Wu HC, Chang CH, Tsou YA, Tsai CW, Lin CC and Bau DT: Significant association of caveolin-1 (CAV1) genotypes with prostate cancer susceptibility in Taiwan. Anticancer Res 31: 745-749, 2011.
23. Wu HC, Chang CH, Tsai RY, Lin CH, Wang RF, Tsai CW, Chen KB, Yao CH, Chiu CF, Bau DT and Lin CC: Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in Taiwan. Anticancer Res 30: 3573-3577, 2010.
24. Wang HC, Liu CS, Chiu CF, Chiang SY, Wang CH, Wang RF, Lin CC, Tsai RY and Bau DT: Significant association of DNA repair gene Ku80 genotypes with breast cancer susceptibility in Taiwan. Anticancer Res 29: 5251-5254, 2009.
25. Wang HC, Chiu CF, Tsai RY, Kuo YS, Chen HS, Wang RF, Tsai CW, Chang CH, Lin CC and Bau DT: Association of genetic polymorphisms of EXO1 gene with risk of breast cancer in Taiwan. Anticancer Res 29: 3897-3901, 2009.
26. Wang HC, Chang WS, Tsai RY, Tsai CW, Liu LC, Su CH, Cheng HN, Tsou YA, Sun SS, Lin CC and Bau DT: Association between ataxia telangiectasia mutated gene polymorphisms and breast cancer in Taiwanese females. Anticancer Res 30: 5217-5221, 2010.
27. Tseng HC, Tsai MH, Chiu CF, Wang CH, Chang NW, Huang CY, Tsai CW, Liang SY, Wang CL and Bau DT: Association of XRCC4 codon 247 polymorphism with oral cancer susceptibility in Taiwan. Anticancer Res 28: 1687-1691, 2008. (Pubitemid 351892945)
28. Chang CH, Wang RF, Tsai RY, Wu HC, Wang CH, Tsai CW, Chang CL, Tsou YA, Liu CS and Bau DT: Significant association of XPD codon 312 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan. Anticancer Res 29: 3903-3907, 2009.
29. Chang CH, Chiu CF, Wang HC, Wu HC, Tsai RY, Tsai CW, Wang RF, Wang CH, Tsou YA and Bau DT: Significant association of ERCC6 single nucleotide polymorphisms with bladder cancer susceptibility in Taiwan. Anticancer Res 29: 5121-5124, 2009.
30. Chang CH, Chiu CF, Liang SY, Wu HC, Chang CL, Tsai CW, Wang HC, Lee HZ and Bau DT: Significant association of Ku80 single nucleotide polymorphisms with bladder cancer susceptibility in Taiwan. Anticancer Res 29: 1275-1279, 2009.
31. Chang CH, Chang CL, Tsai CW, Wu HC, Chiu CF, Wang RF, Liu CS, Lin CC and Bau DT: Significant association of an XRCC4 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan. Anticancer Res 29: 1777-1782, 2009.
32. Wang J, Dong X, Myung K, Hendrickson EA and Reeves WH: Identification of two domains of the p70 Ku protein mediating dimerization with p80 and DNA binding. J Biol Chem 273: 842-848, 1998. (Pubitemid 28049175)
33. Featherstone C and Jackson SP: Ku, a DNA repair protein with multiple cellular functions? Mutat Res 434: 3-15, 1999. (Pubitemid 29240693)
34. Bau DT, Mau YC and Shen CY: The role of BRCA1 in non-homologous end-joining. Cancer Lett 240: 1-8, 2006.
35. Tsai YY, Bau DT, Chiang CC, Cheng YW, Tseng SH and Tsai FJ: Pterygium and genetic polymorphism of DNA double-strand break repair gene Ku70 . Mol Vis 13: 1436-1440, 2007.
36. Wang W, Pan X, Huo X, Yan F, Wang M, Wang D, Gao Y, Cao Q, Luo D, Qin C, Yin C and Zhang Z: A functional polymorphism C-1310G in the promoter region of Ku70/XRCC6 is associated with risk of renal cell carcinoma. Mol Carcinog doi: 10.1002/mc.21914, 2012.
37. Wang W, Gao Y, Yan F, Wang M, Hu F, Wang D, Cao Q, Qin C, Yin C, Zhang Z and Pan X: Association of Ku70 A-31G polymorphism and risk of renal cell carcinoma in a Chinese population. DNA Cell Biol 31: 1314-1320, 2012.
38. Bau DT, Yang MD, Tsou YA, Lin SS, Wu CN, Hsieh HH, Wang RF, Tsai CW, Chang WS, Hsieh HM, Sun SS and Tsai RY: Colorectal cancer and genetic polymorphism of DNA double-strand break repair gene XRCC4 in Taiwan. Anticancer Res 30: 2727-2730, 2010.