Chemical inhibition of bacterial protein tyrosine phosphatase suppresses capsule production

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Standish, Alistair J ^a   Salim, Angela A ^b   Zhang, Hua ^b   Capon, Robert J ^b   Morona, Renato ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENYL PHOSPHATE; ANTIINFECTIVE AGENT; CAPSULE POLYSACCHARIDE B; FASCIOQUINOL E; PROTEIN TYROSINE PHOSPHATASE; TERPENE; TYROSINE; UNCLASSIFIED DRUG; URONIC ACID; VIRULENCE FACTOR; WZB PROTEIN; DITERPENE; SULFATE;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BACTERIAL CAPSULE; BACTERICIDAL ACTIVITY; BACTERIUM ADHERENCE; CONTROLLED STUDY; ESCHERICHIA COLI; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; IC50; KLEBSIELLA PNEUMONIAE; MOUSE; NONHUMAN; PROOF OF CONCEPT; PROTEIN DEPHOSPHORYLATION; RAW 264.7 CELL LINE; STREPTOCOCCUS PNEUMONIAE; ANIMAL; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; MACROPHAGE; METABOLISM; MICROBIOLOGY; PHOSPHORYLATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL CAPSULES; CELL LINE; DITERPENES; MACROPHAGES; MICE; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASES; STREPTOCOCCUS PNEUMONIAE; SULFURIC ACID ESTERS;

EID: 84866917514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036312     Document Type: Article

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