Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly

Journal of Molecular Biology

Volumn 392, Issue 3, 2009, Pages 678-688

  Hagelueken, Gregor ^a   Huang, Hexian ^a   Mainprize, Iain L ^b   Whitfield, Chris ^b   Naismith, James H ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

capsule; enzyme mechanism; kinase; pathogenic bacteria; phosphatase

Indexed keywords

BACTERIAL POLYSACCHARIDE; PHOSPHATE; PROTEIN CPSB; PROTEIN DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN WZB; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL MEMBRANE; BACTERIAL MUTATION; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME STRUCTURE; ESCHERICHIA COLI; GRAM POSITIVE BACTERIUM; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ANALYSIS;

ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA; STREPTOCOCCUS PNEUMONIAE;

BACTERIAL CAPSULES; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; LIGANDS; METALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHATES; PHOSPHOPROTEIN PHOSPHATASES; PROTEIN STRUCTURE, TERTIARY; PROTEIN TYROSINE PHOSPHATASES; STREPTOCOCCUS PNEUMONIAE; SUBSTRATE SPECIFICITY;

EID: 69349088603     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.07.026     Document Type: Article

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