메뉴 건너뛰기




Volumn 287, Issue 40, 2012, Pages 33733-33744

Annexin A2 and A5 serve as new ligands for C1q on apoptotic cells

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXINS; APOPTOTIC; APOPTOTIC CELLS; AS-LIGANDS; AUTOIMMUNE DISEASE; BINDING PROTEINS; CLASSICAL COMPLEMENT PATHWAY; PATHOPHYSIOLOGY; PHOSPHATIDYLSERINE; RISK FACTORS; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 84866914816     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.341339     Document Type: Article
Times cited : (98)

References (53)
  • 1
    • 77955883153 scopus 로고    scopus 로고
    • Complement, a key system for immune surveillance and homeostasis
    • Ricklin, D., Hajishengallis, G., Yang, K., and Lambris, J. D. (2010) Complement, a key system for immune surveillance and homeostasis. Nat. Immunol. 11, 785-797
    • (2010) Nat. Immunol. , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 2
    • 70350041296 scopus 로고    scopus 로고
    • Paths reunited. Initiation of the classical and lectin pathways of complement activation
    • Wallis, R., Mitchell, D. A., Schmid, R., Schwaeble, W. J., and Keeble, A. H. (2010) Paths reunited. Initiation of the classical and lectin pathways of complement activation. Immunobiology 215, 1-11
    • (2010) Immunobiology , vol.215 , pp. 1-11
    • Wallis, R.1    Mitchell, D.A.2    Schmid, R.3    Schwaeble, W.J.4    Keeble, A.H.5
  • 3
    • 0031569975 scopus 로고    scopus 로고
    • C1q Binds Directly and Specifically to Surface Blebs of Apoptotic Human Keratinocytes: Complement Deficiency and Systemic Lupus Erythematosus Revisited
    • Korb, L. C., and Ahearn, J. M. (1997) C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes. Complement deficiency and systemic lupus erythematosus revisited. J. Immunol. 158, 4525-4528 (Pubitemid 127483768)
    • (1997) Journal of Immunology , vol.158 , Issue.10 , pp. 4525-4528
    • Korb, L.C.1    Ahearn, J.M.2
  • 4
    • 0035903289 scopus 로고    scopus 로고
    • C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
    • DOI 10.1084/jem.194.6.781
    • Ogden, C. A., deCathelineau, A., Hoffmann, P. R., Bratton, D., Ghebrehiwet, B., Fadok, V. A., and Henson, P. M. (2001) C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J. Exp. Med. 194, 781-795 (Pubitemid 32983014)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.6 , pp. 781-795
    • Ogden, C.A.1    DeCathelineau, A.2    Hoffmann, P.R.3    Bratton, D.4    Fadok, B.5    Ghebrehiwet, V.A.6    Henson, P.M.7
  • 5
    • 0035284867 scopus 로고    scopus 로고
    • The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells
    • Navratil, J. S., Watkins, S. C., Wisnieski, J. J., and Ahearn, J. M. (2001) The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells. J. Immunol. 166, 3231-3239 (Pubitemid 33117322)
    • (2001) Journal of Immunology , vol.166 , Issue.5 , pp. 3231-3239
    • Navratil, J.S.1    Watkins, S.C.2    Wisnieski, J.J.3    Ahearn, J.M.4
  • 6
    • 0036785571 scopus 로고    scopus 로고
    • Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro. Calreticulin and CD91 as a common collectin receptor complex
    • Vandivier, R. W., Ogden, C. A., Fadok, V. A., Hoffmann, P. R., Brown, K. K., Botto, M., Walport, M. J., Fisher, J. H., Henson, P. M., and Greene, K. E. (2002) Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro. Calreticulin and CD91 as a common collectin receptor complex. J. Immunol. 169, 3978-3986
    • (2002) J. Immunol. , vol.169 , pp. 3978-3986
    • Vandivier, R.W.1    Ogden, C.A.2    Fadok, V.A.3    Hoffmann, P.R.4    Brown, K.K.5    Botto, M.6    Walport, M.J.7    Fisher, J.H.8    Henson, P.M.9    Greene, K.E.10
  • 8
    • 27744503953 scopus 로고    scopus 로고
    • CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells
    • DOI 10.1074/jbc.M506579200
    • Elward, K., Griffiths, M., Mizuno, M., Harris, C. L., Neal, J. W., Morgan, B. P., and Gasque, P. (2005) CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells. J. Biol. Chem. 280, 36342-36354 (Pubitemid 41633908)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.43 , pp. 36342-36354
    • Elward, K.1    Griffiths, M.2    Mizuno, M.3    Harris, C.L.4    Neal, J.W.5    Morgan, B.P.6    Gasque, P.7
  • 9
    • 0026493918 scopus 로고
    • DNA binds and activates complement via residues 14-26 of the human C1q A chain
    • Jiang, H., Cooper, B., Robey, F. A., and Gewurz, H. (1992) DNA binds and activates complement via residues 14-26 of the human C1q A chain. J. Biol. Chem. 267, 25597-25601
    • (1992) J. Biol. Chem. , vol.267 , pp. 25597-25601
    • Jiang, H.1    Cooper, B.2    Robey, F.A.3    Gewurz, H.4
  • 10
    • 0038783609 scopus 로고    scopus 로고
    • Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains
    • Kishore, U., Gupta, S. K., Perdikoulis, M. V., Kojouharova, M. S., Urban, B. C., and Reid, K. B. (2003) Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains. J. Immunol. 171, 812-820 (Pubitemid 36871392)
    • (2003) Journal of Immunology , vol.171 , Issue.2 , pp. 812-820
    • Kishore, U.1    Gupta, S.K.2    Perdikoulis, M.V.3    Kojouharova, M.S.4    Urban, B.C.5    Reid, K.B.M.6
  • 11
    • 3543015529 scopus 로고    scopus 로고
    • Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin
    • DOI 10.1074/jbc.M403763200
    • Palaniyar, N., Nadesalingam, J., Clark, H., Shih, M. J., Dodds, A. W., and Reid, K. B. (2004) Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin. J. Biol. Chem. 279, 32728-32736 (Pubitemid 39014732)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.31 , pp. 32728-32736
    • Palaniyar, N.1    Nadesalingam, J.2    Clark, H.3    Shih, M.J.4    Dodds, A.W.5    Reid, K.B.M.6
  • 12
    • 0344393564 scopus 로고    scopus 로고
    • Interaction of the C1 complex of Complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy
    • DOI 10.1046/j.1432-1033.2003.03870.x
    • Tissot, B., Daniel, R., and Place, C. (2003) Interaction of the C1 complex of complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy. Eur. J. Biochem. 270, 4714-4720 (Pubitemid 37487241)
    • (2003) European Journal of Biochemistry , vol.270 , Issue.23 , pp. 4714-4720
    • Tissot, B.1    Daniel, R.2    Place, C.3
  • 14
    • 0036721697 scopus 로고    scopus 로고
    • Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells
    • Webb, J. H., Blom, A. M., and Dahlbäck, B. (2002) Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. J. Immunol. 169, 2580-2586 (Pubitemid 34921003)
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2580-2586
    • Webb, J.H.1    Blom, A.M.2    Dahlback, B.3
  • 15
    • 35348980673 scopus 로고    scopus 로고
    • C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack
    • DOI 10.1074/jbc.M704354200
    • Trouw, L. A., Bengtsson, A. A., Gelderman, K. A., Dahlbäck, B., Sturfelt, G., and Blom, A. M. (2007) C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack. J. Biol. Chem. 282, 28540-28548 (Pubitemid 47606049)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.39 , pp. 28540-28548
    • Trouw, L.A.1    Bengtsson, A.A.2    Gelderman, K.A.3    Dahlback, B.4    Sturfelt, G.5    Blom, A.M.6
  • 16
    • 22344454254 scopus 로고    scopus 로고
    • C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
    • DOI 10.1084/jem.20050189
    • Trouw, L. A., Nilsson, S. C., Gonçalves, I., Landberg, G., and Blom, A. M. (2005) C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation. J. Exp. Med. 201, 1937-1948 (Pubitemid 41002930)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.12 , pp. 1937-1948
    • Trouw, L.A.1    Nilsson, S.C.2    Goncalves, I.3    Landberg, G.4    Blom, A.M.5
  • 21
    • 79960013939 scopus 로고    scopus 로고
    • Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis
    • Ao, W., Zheng, H., Chen, X. W., Shen, Y., and Yang, C. D. (2011) Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis. Rheumatol. Int. 31, 865-869
    • (2011) Rheumatol. Int. , vol.31 , pp. 865-869
    • Ao, W.1    Zheng, H.2    Chen, X.W.3    Shen, Y.4    Yang, C.D.5
  • 22
    • 84863624989 scopus 로고    scopus 로고
    • Annexin A5 and anti-annexin antibodies in patients with systemic lupus erythematosus
    • Hrycek, A., and Cieślik, P. (2012) Annexin A5 and anti-annexin antibodies in patients with systemic lupus erythematosus. Rheumatol. Int. 32, 1335-1342
    • (2012) Rheumatol. Int. , vol.32 , pp. 1335-1342
    • Hrycek, A.1    Cieślik, P.2
  • 23
    • 0020530378 scopus 로고
    • Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S
    • Dahlbäck, B. (1983) Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S. Biochem. J. 209, 847-856
    • (1983) Biochem. J. , vol.209 , pp. 847-856
    • Dahlbäck, B.1
  • 24
    • 0037210218 scopus 로고    scopus 로고
    • CCP1-4 of the C4b-binding protein α-chain are required for factor I mediated cleavage of complement factor C3b
    • DOI 10.1016/S0161-5890(02)00213-4, PII S0161589002002134
    • Blom, A. M., Kask, L., and Dahlbäck, B. (2003) CCP1-4 of the C4b-binding protein α-chain are required for factor I mediated cleavage of complement factor C3b. Mol. Immunol. 39, 547-556 (Pubitemid 35335833)
    • (2003) Molecular Immunology , vol.39 , Issue.10 , pp. 547-556
    • Blom, A.M.1    Kask, L.2    Dahlback, B.3
  • 25
    • 0019472804 scopus 로고
    • Purification and radiolabeling of human C1q
    • Tenner, A. J., Lesavre, P. H., and Cooper, N. R. (1981) Purification and radiolabeling of human C1q. J. Immunol. 127, 648-653 (Pubitemid 11054682)
    • (1981) Journal of Immunology , vol.127 , Issue.2 , pp. 648-653
    • Tenner, A.J.1    Lesavre, P.H.2    Cooper, N.R.3
  • 26
    • 2642533647 scopus 로고    scopus 로고
    • The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells
    • DOI 10.1074/jbc.C400159200
    • Kask, L., Trouw, L. A., Dahlbäck, B., and Blom, A. M. (2004) The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells. J. Biol. Chem. 279, 23869-23873 (Pubitemid 38725243)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.23 , pp. 23869-23873
    • Kask, L.1    Trouw, L.A.2    Dahlback, B.3    Blom, A.M.4
  • 29
    • 70350435294 scopus 로고    scopus 로고
    • Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma
    • Krisinger, M. J., Guo, L. J., Salvagno, G. L., Guidi, G. C., Lippi, G., and Dahlbäck, B. (2009) Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma. FEBS J. 276, 6586-6602
    • (2009) FEBS J. , vol.276 , pp. 6586-6602
    • Krisinger, M.J.1    Guo, L.J.2    Salvagno, G.L.3    Guidi, G.C.4    Lippi, G.5    Dahlbäck, B.6
  • 30
    • 0027418205 scopus 로고
    • Measurement of co-localization of objects in dual-colour confocal images
    • Manders, E. M., Verbeek, F. J., and Aten, J. A. (1993) Measurement of colocalization of objects in dual-color confocal images. J. Microsc. 169, 375-382 (Pubitemid 23119681)
    • (1993) Journal of Microscopy , vol.169 , Issue.3 , pp. 375-382
    • Manders, E.M.M.1    Verbeek, F.J.2    Aten, J.A.3
  • 31
    • 2442707797 scopus 로고    scopus 로고
    • Nucleosomes are exposed at the cell surface in apoptosis
    • Radic, M., Marion, T., and Monestier, M. (2004) Nucleosomes are exposed at the cell surface in apoptosis. J. Immunol. 172, 6692-6700 (Pubitemid 38669105)
    • (2004) Journal of Immunology , vol.172 , Issue.11 , pp. 6692-6700
    • Radic, M.1    Marion, T.2    Monestier, M.3
  • 33
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke, T. M., and Sandstrom, P. A. (1994) Oxidative stress as a mediator of apoptosis. Immunol. Today 15, 7-10
    • (1994) Immunol. Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 34
    • 70449724676 scopus 로고    scopus 로고
    • Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H
    • Mihlan, M., Stippa, S., Józsi, M., and Zipfel, P. F. (2009) Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H. Cell Death Differ. 16, 1630-1640
    • (2009) Cell Death Differ. , vol.16 , pp. 1630-1640
    • Mihlan, M.1    Stippa, S.2    Józsi, M.3    Zipfel, P.F.4
  • 36
    • 70449710443 scopus 로고    scopus 로고
    • IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells
    • Chen, Y., Park, Y. B., Patel, E., and Silverman, G. J. (2009) IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells. J. Immunol. 182, 6031-6043
    • (2009) J. Immunol. , vol.182 , pp. 6031-6043
    • Chen, Y.1    Park, Y.B.2    Patel, E.3    Silverman, G.J.4
  • 37
    • 0026496332 scopus 로고
    • Serum amyloid P component binds to histones and activates the classical complement pathway
    • Hicks, P. S., Saunero-Nava, L., Du Clos, T. W., and Mold, C. (1992) Serum amyloid P component binds to histones and activates the classical complement pathway. J. Immunol. 149, 3689-3694
    • (1992) J. Immunol. , vol.149 , pp. 3689-3694
    • Hicks, P.S.1    Saunero-Nava, L.2    Du Clos, T.W.3    Mold, C.4
  • 38
    • 0032793635 scopus 로고    scopus 로고
    • DNA levels in circulating immune complexes decrease at severe SLE flares - Correlation with complement component C1q
    • DOI 10.1006/jaut.1999.0300
    • Bengtsson, A., Nezlin, R., Shoenfeld, Y., and Sturfelt, G. (1999) DNA levels in circulating immune complexes decrease at severe SLE flares. Correlation with complement component C1q. J. Autoimmun. 13, 111-119 (Pubitemid 29367014)
    • (1999) Journal of Autoimmunity , vol.13 , Issue.1 , pp. 111-119
    • Bengtsson, A.1    Nezlin, R.2    Shoenfeld, Y.3    Sturfelt, G.4
  • 40
    • 0038735621 scopus 로고    scopus 로고
    • Clinical significance of measurement of plasma annexin V concentration of patients in the emergency room
    • DOI 10.1016/S0300-9572(03)00034-0
    • Matsuda, R., Kaneko, N., Kikuchi, M., Chiwaki, F., Toda, M., Ieiri, T., Horikawa, Y., Shimizu, M., and Shimamoto, K. (2003) Clinical significance of measurement of plasma annexin V concentration of patients in the emergency room. Resuscitation 57, 171-177 (Pubitemid 36556185)
    • (2003) Resuscitation , vol.57 , Issue.2 , pp. 171-177
    • Matsuda, R.1    Kaneko, N.2    Kikuchi, M.3    Chiwaki, F.4    Toda, M.5    Ieiri, T.6    Horikawa, Y.7    Shimizu, M.8    Shimamoto, K.9
  • 41
    • 84858006658 scopus 로고    scopus 로고
    • Human complement factor H modulates C1q-mediated phagocytosis of apoptotic cells
    • Kang, Y. H., Urban, B. C., Sim, R. B., and Kishore, U. (2012) Human complement factor H modulates C1q-mediated phagocytosis of apoptotic cells. Immunobiology 217, 455-464
    • (2012) Immunobiology , vol.217 , pp. 455-464
    • Kang, Y.H.1    Urban, B.C.2    Sim, R.B.3    Kishore, U.4
  • 43
    • 15244353241 scopus 로고    scopus 로고
    • Role of anti-C1q autoantibodies in the pathogenesis of lupus nephritis
    • DOI 10.1517/14712598.5.2.243
    • Trouw, L. A., and Daha, M. R. (2005) Role of anti-C1q autoantibodies in the pathogenesis of lupus nephritis. Expert Opin. Biol. Ther. 5, 243-251 (Pubitemid 40388854)
    • (2005) Expert Opinion on Biological Therapy , vol.5 , Issue.2 , pp. 243-251
    • Trouw, L.A.1    Daha, M.R.2
  • 45
    • 37349066319 scopus 로고    scopus 로고
    • Complement deficiencies and systemic lupus erythematosus
    • DOI 10.1080/08916930701510673, PII 788414850
    • Truedsson, L., Bengtsson, A. A., and Sturfelt, G. (2007) Complement deficiencies and systemic lupus erythematosus. Autoimmunity 40, 560-566 (Pubitemid 350302182)
    • (2007) Autoimmunity , vol.40 , Issue.8 , pp. 560-566
    • Truedsson, L.1    Bengtsson, A.A.2    Sturfelt, G.3
  • 48
    • 70349769369 scopus 로고    scopus 로고
    • C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells. A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis
    • Lood, C., Gullstrand, B., Truedsson, L., Olin, A. I., Alm, G. V., Rönnblom, L., Sturfelt, G., Eloranta, M. L., and Bengtsson, A. A. (2009) C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells. A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis. Arthritis Rheum. 60, 3081-3090
    • (2009) Arthritis Rheum. , vol.60 , pp. 3081-3090
    • Lood, C.1    Gullstrand, B.2    Truedsson, L.3    Olin, A.I.4    Alm, G.V.5    Rönnblom, L.6    Sturfelt, G.7    Eloranta, M.L.8    Bengtsson, A.A.9
  • 49
    • 73949145491 scopus 로고    scopus 로고
    • C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells
    • Fraser, D. A., Laust, A. K., Nelson, E. L., and Tenner, A. J. (2009) C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. J. Immunol. 183, 6175-6185
    • (2009) J. Immunol. , vol.183 , pp. 6175-6185
    • Fraser, D.A.1    Laust, A.K.2    Nelson, E.L.3    Tenner, A.J.4
  • 50
    • 73949103664 scopus 로고    scopus 로고
    • C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production
    • Fraser, D. A., Pisalyaput, K., and Tenner, A. J. (2010) C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production. J. Neurochem. 112, 733-743
    • (2010) J. Neurochem. , vol.112 , pp. 733-743
    • Fraser, D.A.1    Pisalyaput, K.2    Tenner, A.J.3
  • 51
    • 0021822458 scopus 로고
    • Sequential studies of complement activation in systemic lupus erythematosus
    • Sturfelt, G., Johnson, U., and Sjöholm, A. G. (1985) Sequential studies of complement activation in systemic lupus erythematosus. Scand. J. Rheumatol. 14, 184-196 (Pubitemid 15057860)
    • (1985) Scandinavian Journal of Rheumatology , vol.14 , Issue.2 , pp. 184-196
    • Sturfelt, G.1    Johnson, U.2    Sjoholm, A.G.3
  • 52
    • 3242706096 scopus 로고    scopus 로고
    • Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro
    • Choi, J. J., Reich, C. F., 3rd, and Pisetsky, D. S. (2004) Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. Scand. J. Immunol. 60, 159-166
    • (2004) Scand. J. Immunol. , vol.60 , pp. 159-166
    • Choi, J.J.1    Reich III, C.F.2    Pisetsky, D.S.3
  • 53
    • 79955002341 scopus 로고    scopus 로고
    • Decreased secretion of MMP by nonlesional late-stage scleroderma fibroblasts after selection via activation of the apoptotic Fas-pathway
    • Chabaud, S., Corriveau, M. P., Grodzicky, T., Senécal, J. L., Chartier, S., Raymond, Y., and Moulin, V. J. (2011) Decreased secretion of MMP by nonlesional late-stage scleroderma fibroblasts after selection via activation of the apoptotic Fas-pathway. J. Cell. Physiol. 226, 1907-1914
    • (2011) J. Cell. Physiol. , vol.226 , pp. 1907-1914
    • Chabaud, S.1    Corriveau, M.P.2    Grodzicky, T.3    Senécal, J.L.4    Chartier, S.5    Raymond, Y.6    Moulin, V.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.