Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells

Biochemical Journal

Volumn 447, Issue 2, 2012, Pages 313-320

  Kang, Shin Ae ^a   Cho, Hyun Soo ^a   Yoon, Jong Bok ^a   Chung, In Kwon ^a   Lee, Seung Taek ^a  

^a Yonsei University   (South Korea)

Author keywords

C terminus of Hsc70 (heat shock cognate 70) interacting protein (CHIP); Heat shock protein 90 (Hsp90); Proteasomal degradation; Protein stability; PTK6 protein tyrosine kinase 6 (PTK6); Tyrosine kinase

Indexed keywords

C TERMINUS OF HEAT SHOCK COGNATE 70 INTERACTING PROTEIN; CHAPERONE; GELDANAMYCIN; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 90; PROTEASOME; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CANCER CELL; CATALYSIS; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

BENZOQUINONES; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HEK293 CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; NEOPLASM PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-TYROSINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84866870218     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120803     Document Type: Article

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