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Volumn 13, Issue 10, 2012, Pages

Pharmacogenetic biomarkers for the prediction of response to antiangiogenic treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AXITINIB; BEVACIZUMAB; BIOLOGICAL MARKER; CAPECITABINE; CARBOPLATIN PLUS PACLITAXEL; CYCLOPHOSPHAMIDE; DOCETAXEL; ERLOTINIB PLUS GEMCITABINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; PACLITAXEL; PAZOPANIB; PLACEBO; SORAFENIB; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

EID: 84866849940     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(12)70275-9     Document Type: Review
Times cited : (37)

References (55)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman J Tumor angiogenesis: therapeutic implications. N Engl J Med 1971, 285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel RS Tumor angiogenesis. N Engl J Med 2008, 358:2039-2049.
    • (2008) N Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 3
    • 79959304867 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapy for breast cancer: can we pick the winners?
    • Schneider BP, Sledge GW Anti-vascular endothelial growth factor therapy for breast cancer: can we pick the winners?. J Clin Oncol 2011, 29:2444-2447.
    • (2011) J Clin Oncol , vol.29 , pp. 2444-2447
    • Schneider, B.P.1    Sledge, G.W.2
  • 4
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007, 357:2666-2676.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 5
    • 77954700380 scopus 로고    scopus 로고
    • Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • Miles DW, Chan A, Dirix LY, et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2010, 28:3239-3247.
    • (2010) J Clin Oncol , vol.28 , pp. 3239-3247
    • Miles, D.W.1    Chan, A.2    Dirix, L.Y.3
  • 6
    • 79953874259 scopus 로고    scopus 로고
    • RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
    • Robert NJ, Dieras V, Glaspy J, et al. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer. J Clin Oncol 2011, 29:1252-1260.
    • (2011) J Clin Oncol , vol.29 , pp. 1252-1260
    • Robert, N.J.1    Dieras, V.2    Glaspy, J.3
  • 7
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial
    • Rini BI, Escudier B, Tomczak P, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 2011, 378:1931-1939.
    • (2011) Lancet , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 8
    • 0031443206 scopus 로고    scopus 로고
    • A cancer therapy resistant to resistance
    • Kerbel RS A cancer therapy resistant to resistance. Nature 1997, 390:335-336.
    • (1997) Nature , vol.390 , pp. 335-336
    • Kerbel, R.S.1
  • 9
    • 84938095333 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) inhibition-a critical review
    • Moreira IS, Fernandes PA, Ramos MJ Vascular endothelial growth factor (VEGF) inhibition-a critical review. Anticancer Agents Med Chem 2007, 7:223-245.
    • (2007) Anticancer Agents Med Chem , vol.7 , pp. 223-245
    • Moreira, I.S.1    Fernandes, P.A.2    Ramos, M.J.3
  • 10
    • 77952491738 scopus 로고    scopus 로고
    • Carboplatin/pemetrexed/bevacizumab in the treatment of patients with advanced non-small-cell lung cancer: a single-institution experience
    • Malhotra B, Evans T, Weiss J, et al. Carboplatin/pemetrexed/bevacizumab in the treatment of patients with advanced non-small-cell lung cancer: a single-institution experience. Clin Lung Cancer 2010, 11:192-197.
    • (2010) Clin Lung Cancer , vol.11 , pp. 192-197
    • Malhotra, B.1    Evans, T.2    Weiss, J.3
  • 11
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004, 350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 12
    • 65549122619 scopus 로고    scopus 로고
    • Management of hypertension in angiogenesis inhibitor-treated patients
    • Izzedine H, Ederhy S, Goldwasser F, et al. Management of hypertension in angiogenesis inhibitor-treated patients. Ann Oncol 2009, 20:807-815.
    • (2009) Ann Oncol , vol.20 , pp. 807-815
    • Izzedine, H.1    Ederhy, S.2    Goldwasser, F.3
  • 13
    • 36049026182 scopus 로고    scopus 로고
    • Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitors
    • Cabebe E, Wakelee H Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitors. Curr Treat Options Oncol 2007, 8:15-27.
    • (2007) Curr Treat Options Oncol , vol.8 , pp. 15-27
    • Cabebe, E.1    Wakelee, H.2
  • 14
    • 44649151405 scopus 로고    scopus 로고
    • Axitinib, a novel anti-angiogenic drug with promising activity in various solid tumors
    • Choueiri TK Axitinib, a novel anti-angiogenic drug with promising activity in various solid tumors. Curr Opin Investig Drugs 2008, 9:658-671.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 658-671
    • Choueiri, T.K.1
  • 15
    • 49249087039 scopus 로고    scopus 로고
    • Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma
    • Rini BI, Michaelson MD, Rosenberg JE, et al. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J Clin Oncol 2008, 26:3743-3748.
    • (2008) J Clin Oncol , vol.26 , pp. 3743-3748
    • Rini, B.I.1    Michaelson, M.D.2    Rosenberg, J.E.3
  • 16
    • 68849124283 scopus 로고    scopus 로고
    • Toxicity associated with the long-term use of targeted therapies in patients with advanced renal cell carcinoma
    • Shepard DR, Garcia JA Toxicity associated with the long-term use of targeted therapies in patients with advanced renal cell carcinoma. Expert Rev Anticancer Ther 2009, 9:795-805.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 795-805
    • Shepard, D.R.1    Garcia, J.A.2
  • 17
    • 67650380136 scopus 로고    scopus 로고
    • Biomarkers of response and resistance to antiangiogenic therapy
    • Jain RK, Duda DG, Willett CG, et al. Biomarkers of response and resistance to antiangiogenic therapy. Nat Rev Clin Oncol 2009, 6:327-338.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 327-338
    • Jain, R.K.1    Duda, D.G.2    Willett, C.G.3
  • 18
    • 33644823334 scopus 로고    scopus 로고
    • Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer
    • Jubb AM, Hurwitz HI, Bai W, et al. Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer. J Clin Oncol 2006, 24:217-227.
    • (2006) J Clin Oncol , vol.24 , pp. 217-227
    • Jubb, A.M.1    Hurwitz, H.I.2    Bai, W.3
  • 19
    • 79251473728 scopus 로고    scopus 로고
    • Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer
    • Jubb AM, Miller KD, Rugo HS, et al. Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer. Clin Cancer Res 2011, 17:372-381.
    • (2011) Clin Cancer Res , vol.17 , pp. 372-381
    • Jubb, A.M.1    Miller, K.D.2    Rugo, H.S.3
  • 20
    • 84856806836 scopus 로고    scopus 로고
    • First results of AVEREL, a randomized phase III trial to evaluate bevacizumab (BEV) in combination with trastuzumab (H) + docetaxel (DOC) as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer (LR/mBC)
    • Gianni L, Romieu G, Lichinitser M, et al. First results of AVEREL, a randomized phase III trial to evaluate bevacizumab (BEV) in combination with trastuzumab (H) + docetaxel (DOC) as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer (LR/mBC). Cancer Res 2011, 71(suppl 24):S4-S8.
    • (2011) Cancer Res , vol.71 , Issue.SUPPL. 24
    • Gianni, L.1    Romieu, G.2    Lichinitser, M.3
  • 21
    • 78149416616 scopus 로고    scopus 로고
    • Resequencing of the vascular endothelial growth factor promoter reveals haplotype structure and functional diversity
    • Radovich M, Hancock BA, Kassem N, Mi D, Skaar TC, Schneider BP Resequencing of the vascular endothelial growth factor promoter reveals haplotype structure and functional diversity. Angiogenesis 2010, 13:211-218.
    • (2010) Angiogenesis , vol.13 , pp. 211-218
    • Radovich, M.1    Hancock, B.A.2    Kassem, N.3    Mi, D.4    Skaar, T.C.5    Schneider, B.P.6
  • 22
    • 53749093040 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
    • Schneider BP, Wang M, Radovich M, et al. Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100. J Clin Oncol 2008, 26:4672-4678.
    • (2008) J Clin Oncol , vol.26 , pp. 4672-4678
    • Schneider, B.P.1    Wang, M.2    Radovich, M.3
  • 23
    • 84873614190 scopus 로고    scopus 로고
    • Polymorphism analysis in the AVADO randomised phase III trial of first-line bevacizumab (BEV) combined with docetaxel in HER2-negative metastatic breast cancer (mBC)
    • (abstr 1423).
    • Miles DW, De Haas SL, Romieu G, et al. Polymorphism analysis in the AVADO randomised phase III trial of first-line bevacizumab (BEV) combined with docetaxel in HER2-negative metastatic breast cancer (mBC). Eur J Cancer 2011, 47(suppl 1):204. (abstr 1423).
    • (2011) Eur J Cancer , vol.47 , Issue.SUPPL. 1 , pp. 204
    • Miles, D.W.1    De Haas, S.L.2    Romieu, G.3
  • 24
    • 78149465735 scopus 로고    scopus 로고
    • Irinotecan/capecitabine (XELIRI) plus bevacizumab versus irinotecan/fluorouracil/leucovorin (FOLFIRI) plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a randomized phase III trial of the Hellenic Cooperative Oncology Group (HeCOG)
    • abstr 3541.
    • Pectasides DG, Xanthakis I, Makatsoris T, et al. Irinotecan/capecitabine (XELIRI) plus bevacizumab versus irinotecan/fluorouracil/leucovorin (FOLFIRI) plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a randomized phase III trial of the Hellenic Cooperative Oncology Group (HeCOG). Proc Am Soc Clin Oncol 2010, 28(suppl). abstr 3541.
    • (2010) Proc Am Soc Clin Oncol , vol.28 , Issue.SUPPL.
    • Pectasides, D.G.1    Xanthakis, I.2    Makatsoris, T.3
  • 25
    • 84870054412 scopus 로고    scopus 로고
    • Vascular endothelial growth factor polymorphisms and clinical outcome in colorectal cancer patients treated with irinotecan-based chemotherapy and bevacizumab
    • published online Aug 16.
    • Koutras AK, Antonacopoulou AG, Eleftheraki AG, et al. Vascular endothelial growth factor polymorphisms and clinical outcome in colorectal cancer patients treated with irinotecan-based chemotherapy and bevacizumab. Pharmacogenomics J 2011, published online Aug 16. 10.1038/tpj.2011.37.
    • (2011) Pharmacogenomics J
    • Koutras, A.K.1    Antonacopoulou, A.G.2    Eleftheraki, A.G.3
  • 26
    • 79951723590 scopus 로고    scopus 로고
    • Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab
    • Formica V, Palmirotta R, Del Monte G, et al. Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab. Int J Colorectal Dis 2011, 26:143-151.
    • (2011) Int J Colorectal Dis , vol.26 , pp. 143-151
    • Formica, V.1    Palmirotta, R.2    Del Monte, G.3
  • 27
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355:2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 28
    • 69949111615 scopus 로고    scopus 로고
    • Genetic variants in angiogenesis pathway associated with clinical outcome in NSCLC patients (pts) treated with bevacizumab in combination with carboplatin and paclitaxel: subset pharmacogenetic analysis of ECOG 4599
    • abstr 8032.
    • Zhang W, Dahlberg SE, Yang D, et al. Genetic variants in angiogenesis pathway associated with clinical outcome in NSCLC patients (pts) treated with bevacizumab in combination with carboplatin and paclitaxel: subset pharmacogenetic analysis of ECOG 4599. Proc Am Soc Clin Oncol 2009, 27(suppl). abstr 8032.
    • (2009) Proc Am Soc Clin Oncol , vol.27 , Issue.SUPPL.
    • Zhang, W.1    Dahlberg, S.E.2    Yang, D.3
  • 29
    • 58149346076 scopus 로고    scopus 로고
    • Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab
    • Schultheis AM, Lurje G, Rhodes KE, et al. Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab. Clin Cancer Res 2008, 14:7554-7563.
    • (2008) Clin Cancer Res , vol.14 , pp. 7554-7563
    • Schultheis, A.M.1    Lurje, G.2    Rhodes, K.E.3
  • 30
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    • Van Cutsem E, Vervenne WL, Bennouna J, et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. J Clin Oncol 2009, 27:2231-2237.
    • (2009) J Clin Oncol , vol.27 , pp. 2231-2237
    • Van Cutsem, E.1    Vervenne, W.L.2    Bennouna, J.3
  • 31
    • 84863092492 scopus 로고    scopus 로고
    • VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data for the AViTA and AVOREN randomised trials
    • Lambrechts D, Claes B, Delmar P, et al. VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data for the AViTA and AVOREN randomised trials. Lancet Oncol 2012, 13:724-733.
    • (2012) Lancet Oncol , vol.13 , pp. 724-733
    • Lambrechts, D.1    Claes, B.2    Delmar, P.3
  • 32
    • 75749090050 scopus 로고    scopus 로고
    • Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma
    • Hutson TE, Davis ID, Machiels J-PH, et al. Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma. J Clin Oncol 2010, 28:475-480.
    • (2010) J Clin Oncol , vol.28 , pp. 475-480
    • Hutson, T.E.1    Davis, I.D.2    Machiels, J.-P.H.3
  • 33
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
    • Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010, 28:1061-1068.
    • (2010) J Clin Oncol , vol.28 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3
  • 34
    • 79959316184 scopus 로고    scopus 로고
    • Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes
    • Xu C-F, Bing NX, Ball HA, et al. Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. J Clin Oncol 2011, 29:2557-2564.
    • (2011) J Clin Oncol , vol.29 , pp. 2557-2564
    • Xu, C.-F.1    Bing, N.X.2    Ball, H.A.3
  • 35
    • 81255160848 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
    • Garcia-Donas J, Esteban E, Leandro-García LJ, et al. Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study. Lancet Oncol 2011, 12:1143-1150.
    • (2011) Lancet Oncol , vol.12 , pp. 1143-1150
    • Garcia-Donas, J.1    Esteban, E.2    Leandro-García, L.J.3
  • 36
    • 79551701442 scopus 로고    scopus 로고
    • Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib
    • van der Veldt AAM, Eechoute K, Gelderblom H, et al. Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib. Clin Cancer Res 2011, 17:620-629.
    • (2011) Clin Cancer Res , vol.17 , pp. 620-629
    • van der Veldt, A.A.M.1    Eechoute, K.2    Gelderblom, H.3
  • 37
    • 84863338437 scopus 로고    scopus 로고
    • Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib
    • Kim JJ, Vaziri SA, Rini BI, et al. Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib. Cancer 2011, 118:1946-1954.
    • (2011) Cancer , vol.118 , pp. 1946-1954
    • Kim, J.J.1    Vaziri, S.A.2    Rini, B.I.3
  • 38
    • 65349161533 scopus 로고    scopus 로고
    • A randomized discontinuation phase II study of sorafenib versus placebo in patients with non-small cell lung cancer who have failed at least two prior chemotherapy regimens: E2501
    • abstr 8014.
    • Schiller JH, Lee JW, Hanna NH, Traynor AM, Carbone DP A randomized discontinuation phase II study of sorafenib versus placebo in patients with non-small cell lung cancer who have failed at least two prior chemotherapy regimens: E2501. Proc Am Soc Clin Oncol 2008, 26(suppl). abstr 8014.
    • (2008) Proc Am Soc Clin Oncol , vol.26 , Issue.SUPPL.
    • Schiller, J.H.1    Lee, J.W.2    Hanna, N.H.3    Traynor, A.M.4    Carbone, D.P.5
  • 39
    • 79952261009 scopus 로고    scopus 로고
    • Use of germline polymorphisms in VEGF to predict tumor response and progression-free survival in non-small cell lung cancer (NSCLC) patients treated with sorafenib: subset pharmacogenetic analysis of Eastern Cooperative Oncology Group (ECOG) trial E2501
    • abstr 7607.
    • Zhang W, Lee J, Schiller JH, Carbone DP, Chung CH, Lenz H Use of germline polymorphisms in VEGF to predict tumor response and progression-free survival in non-small cell lung cancer (NSCLC) patients treated with sorafenib: subset pharmacogenetic analysis of Eastern Cooperative Oncology Group (ECOG) trial E2501. Proc Am Soc Clin Oncol 2010, 28(suppl). abstr 7607.
    • (2010) Proc Am Soc Clin Oncol , vol.28 , Issue.SUPPL.
    • Zhang, W.1    Lee, J.2    Schiller, J.H.3    Carbone, D.P.4    Chung, C.H.5    Lenz, H.6
  • 40
    • 79952799202 scopus 로고    scopus 로고
    • Phase I study of sorafenib (S) with gemcitabine (G)-based radiotherapy (G-RT) in patients (pts) with locally advanced unresectable pancreatic adenocarcinoma (LAUPC)
    • abstr 4139.
    • Anderson S, Cardenes H, Akisik F, et al. Phase I study of sorafenib (S) with gemcitabine (G)-based radiotherapy (G-RT) in patients (pts) with locally advanced unresectable pancreatic adenocarcinoma (LAUPC). Proc Am Soc Clin Oncol 2010, 28(suppl). abstr 4139.
    • (2010) Proc Am Soc Clin Oncol , vol.28 , Issue.SUPPL.
    • Anderson, S.1    Cardenes, H.2    Akisik, F.3
  • 41
    • 80053008404 scopus 로고    scopus 로고
    • Patient-reported outcomes (PROs) in a phase III AXIS trial of axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC)
    • abstr 4504.
    • Cella D, Escudier B, Rini BI, et al. Patient-reported outcomes (PROs) in a phase III AXIS trial of axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC). Proc Am Soc Clin Oncol 2011, 29(suppl). abstr 4504.
    • (2011) Proc Am Soc Clin Oncol , vol.29 , Issue.SUPPL.
    • Cella, D.1    Escudier, B.2    Rini, B.I.3
  • 42
    • 84870661169 scopus 로고    scopus 로고
    • Association of single nucleotide polymorphisms in VEGF pathway genes with progression-free survival and blood pressure in metastatic renal cell carcinoma in phase 3 AXIS trial of axitinib versus sorafenib (AXIS trial)
    • abstr 7103.
    • Escudier B, Loomis AK, Kaprin A, et al. Association of single nucleotide polymorphisms in VEGF pathway genes with progression-free survival and blood pressure in metastatic renal cell carcinoma in phase 3 AXIS trial of axitinib versus sorafenib (AXIS trial). Eur J Cancer 2011, 47(suppl 1). abstr 7103.
    • (2011) Eur J Cancer , vol.47 , Issue.SUPPL. 1
    • Escudier, B.1    Loomis, A.K.2    Kaprin, A.3
  • 43
    • 69949107753 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor genetic variability in cancer
    • Schneider BP, Radovich M, Miller KD The role of vascular endothelial growth factor genetic variability in cancer. Clin Cancer Res 2009, 15:5297-5302.
    • (2009) Clin Cancer Res , vol.15 , pp. 5297-5302
    • Schneider, B.P.1    Radovich, M.2    Miller, K.D.3
  • 44
    • 36749052895 scopus 로고    scopus 로고
    • Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
    • Ebos JML, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc Natl Acacd Sci 2007, 104:17069-17074.
    • (2007) Proc Natl Acacd Sci , vol.104 , pp. 17069-17074
    • Ebos, J.M.L.1    Lee, C.R.2    Christensen, J.G.3    Mutsaers, A.J.4    Kerbel, R.S.5
  • 45
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009, 15:220-231.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3
  • 46
    • 79951673901 scopus 로고    scopus 로고
    • Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
    • Osterlund P, Soveri LM, Isoniemi H, Poussa T, Alanko T, Bono P Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy. Br J Cancer 2011, 104:599-604.
    • (2011) Br J Cancer , vol.104 , pp. 599-604
    • Osterlund, P.1    Soveri, L.M.2    Isoniemi, H.3    Poussa, T.4    Alanko, T.5    Bono, P.6
  • 47
    • 79955767772 scopus 로고    scopus 로고
    • Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib
    • Rini BI, Cohen DP, Lu DR, et al. Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst 2011, 103:763-773.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 763-773
    • Rini, B.I.1    Cohen, D.P.2    Lu, D.R.3
  • 48
    • 77955240423 scopus 로고    scopus 로고
    • Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib
    • Jain L, Sissung TM, Danesi R, et al. Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib. J Exp Clin Cancer Res 2010, 29:95.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 95
    • Jain, L.1    Sissung, T.M.2    Danesi, R.3
  • 49
    • 78049399444 scopus 로고    scopus 로고
    • Analysis of early hypertension (HTN) and clinical outcome with bevacizumab (BV)
    • abstr 3039.
    • Hurwitz H, Douglas PS, Middleton JP, et al. Analysis of early hypertension (HTN) and clinical outcome with bevacizumab (BV). Proc Am Soc Clin Oncol 2010, 28(suppl). abstr 3039.
    • (2010) Proc Am Soc Clin Oncol , vol.28 , Issue.SUPPL.
    • Hurwitz, H.1    Douglas, P.S.2    Middleton, J.P.3
  • 50
    • 70349342710 scopus 로고    scopus 로고
    • Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity
    • van Erp NP, Eechoute K, van der Veldt AA, et al. Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity. J Clin Oncol 2009, 27:4406-4412.
    • (2009) J Clin Oncol , vol.27 , pp. 4406-4412
    • van Erp, N.P.1    Eechoute, K.2    van der Veldt, A.A.3
  • 51
    • 79953283356 scopus 로고    scopus 로고
    • Genetic interactions in cancer progression and treatment
    • Ashworth A, Lord CJ, Reis-Filho JS Genetic interactions in cancer progression and treatment. Cell 2011, 145:30-38.
    • (2011) Cell , vol.145 , pp. 30-38
    • Ashworth, A.1    Lord, C.J.2    Reis-Filho, J.S.3
  • 52
    • 33750310901 scopus 로고    scopus 로고
    • Reporting recommendations for tumor marker prognostic studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W, et al. Reporting recommendations for tumor marker prognostic studies (REMARK). Breast Cancer Res Treat 2006, 100:229-235.
    • (2006) Breast Cancer Res Treat , vol.100 , pp. 229-235
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 53
    • 70449420123 scopus 로고    scopus 로고
    • Use of archived specimens in evaluation of prognostic and predictive biomarkers
    • Simon RM, Paik S, Hayes DF Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 2009, 101:1446-1452.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1446-1452
    • Simon, R.M.1    Paik, S.2    Hayes, D.F.3
  • 55
    • 84855541851 scopus 로고    scopus 로고
    • Genetic associations with taxane-induced neuropathy by a genome-wide association study (GWAS) in E5103
    • abstr 1000.
    • Schneider BP, Li L, Miller K, et al. Genetic associations with taxane-induced neuropathy by a genome-wide association study (GWAS) in E5103. Proc Am Soc Clin Oncol 2011, 29(suppl). abstr 1000.
    • (2011) Proc Am Soc Clin Oncol , vol.29 , Issue.SUPPL.
    • Schneider, B.P.1    Li, L.2    Miller, K.3


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