Affect expression and self-regulation capacities of infants exposed in utero to psychotropics

Frontiers in Psychiatry

Volumn 3, Issue FEB, 2012, Pages

  Reebye, Pratibha N ^a   Ng, Tammy W C ^b   Misri, Shaila ^c   Stikarovska, Irena ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Affect expression; Gestational exposure; Infants; Psychotropics; Self regulation

Indexed keywords

CLONAZEPAM; SEROTONIN UPTAKE INHIBITOR;

AFFECT; ANGER; ANXIETY DISORDER; ARTICLE; AUTOREGULATION; AVERTING BEHAVIOR; AVOIDANCE BEHAVIOR; BEHAVIOR; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; HOSTILITY; HUMAN; INFANT; MALE; MATERNAL ATTITUDE; MATERNAL NEGATIVITY; MATERNAL SENSITIVITY; MOOD; MOTHER CHILD RELATION; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NEGATIVE AFFECT; PARENT CHILD EARLY RELATIONAL ASSESSMENT SCALE; PLAY; POSITIVE AFFECT; PRENATAL DRUG EXPOSURE; RESISTANCE BEHAVIOR; SOBER MOOD; SOCIAL INTERACTION; TASK PERFORMANCE;

EID: 84866847930     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2012.00011     Document Type: Article

References (62)

1. Aitken, A. R., and Tork, I. (1988). Early development of serotonin-containing neurons and pathways as seen in wholemount preparations of the fetal rat brain. J. Comp. Neurol. 274, 32-47.
2. Bakker, M. K., Kolling, P., Van Den Berg, P. B., De Walle, H. E., and De Jong Van Den Berg, L. T. (2008). Increase in use of selective serotonin reuptake inhibitors in pregnancy during the last decade, a population-based cohort study from the Netherlands. Br. J. Clin. Pharmacol. 65, 600-606.
3. Bayley, N. (1993). Bayley Scales of Infant Development Second Edn. San Antonio: The Psychological Cor-portation.
4. Bernier, A., Carlson, S. M., and Whipple, N. (2010). From external regulation to self-regulation: early parenting precursors of young children's executive functioning. Child Dev. 81, 326-339.
5. Buitelaar, J. K., Huizink, A. C., Mulder, E. J., De Medina, P. G., and Visser, G. H. (2003). Prenatal stress and cognitive development and temperament in infants. Neurobiol. Aging 24(Suppl. 1), S53-S60; discussion S67-S68.
6. Calkins, S. D., and Fox, N. A. (2002). Self-regulatory processes in early personality development: a multilevel approach to the study of childhood social withdrawal and aggression. Dev. Psychopathol. 14, 477-498.
7. Campbell, S. B., Brownell, C. A., Hungerford, A., Spieker, S. I., Mohan, R., and Blessing, J. S. (2004). The course of maternal depressive symptoms and maternal sensitivity as predictors of attachment security at 36 months. Dev. Psychopathol. 16, 231-252.
8. Carter, A.S., Garrity-Rokous, F.E., Chazan-Cohen, R., Little, C., and Briggs-Gowan, M.J. (2001).Maternal depressionandcomorbidity: predictingearlyparenting, attachment security,andtoddlersocial-emotional problemsandcompetencies. J. Am.Acad.ChildAdolesc. Psychiatry 40, 18-26.
9. Casper, R. C., Fleisher, B. E., Lee-Ancajas, J. C., Gilles, A., Gaylor, E., Debattista, A., and Hoyme, H. E. (2003). Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J. Pediatr. 142, 402-408.
10. Casper, R. C., Gilles, A. A., Fleisher, B. E., Baran, J., Enns, G., and Lazzeroni, L. C. (2011). Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antide-pressants: effects on neonatal adaptation and psychomotor development. Psychopharmacology (Berl.) 217,211-219.
11. Clark, R. (1985). The Parent-Child Early Relational Assessment. Madison: Department of Psychiatry, University of Wisconsin Medical School.
12. Clarke, A. S., and Schneider, M. L. (1997). Effects of prenatal stress on behavior in adolescent rhesus monkey. Ann. N. Y. Acad. Sci. 807, 490-491.
13. Cohen, L. S., Heller, V. L., and Rosenbaum, J. F. (1989). Treatment guidelines for psychotropic drug use in pregnancy. Psychosomatics 30, 25-33.
14. Davids, A., Holden, R. H., and Gray, G. B. (1963). Maternal anxiety during pregnancy and adequacy of mother and child adjustment eight months following childbirth. Child Dev. 34, 993-1002.
15. Deave, T., Heron, J., Evans, J., and Emond, A. (2008). The impact of maternal depression in pregnancy on early child development. BJOG 115, 1043-1051.
16. Einarson, A., Fatoye, B., Sarkar, M., Lavigne, S. V., Brochu, J., Chambers, C., Mastroiacovo, P., Addis, A., Matsui, D., Schuler, L., Einarson, T. R., and Koren, G. (2001). Pregnancy outcome following gestational exposure to venlafaxine: a multicenter prospective controlled study. Am. J. Psychiatry 158, 1728-1730.
17. Eisenberg, N., Guthrie, I. K., Fabes, R. A., Shepard, S., Losoya, S., Murphy, B. C., Jones, S., Poulin, R., and Reiser, M. (2000). Prediction of elementary school children's externalizing problem behaviors from atten-tional and behavioral regulation and negative emotionality. Child Dev. 71, 1367-1382.
18. Field, T. (1998). Early interventions for infants of depressed mothers. Pediatrics 102, 1305-1310.
19. Field, T. (2011). Prenatal depression effects on early development: a review. Infant Behav. Dev. 34, 1-14.
20. Fonagy, P., Gergely, G., Target, M., and Jurist, E. L. (2002). Affect Regulation, Mentalization, and the Development of the Self. New York: Other Press.
21. Gentile, S. (2005). SSRIs in pregnancy and lactation: emphasis on neurode-velopmental outcome. CNS Drugs 19, 623-633.
22. Gentile, S. (2010). Neurodevelopmen-tal effects of prenatal exposure to psychotropic medications. Depress. Anxiety 27, 675-686.
23. Gentile, S., and Bellantuono, C. (2009). Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine. J. Clin. Psychiatry 70, 414-422.
24. Gianino, A., and Tronick, E. Z. (1988). "The mutual regulation model: the infant's self and interactive regulation and coping and defensive capacities," in Stress and Coping, eds T. Field, P. Mccabe, and N. Schnei-derman (Hillside, NJ: Lawrence Erl-baum Associates), 47-68.
25. Goldstein, D. J., Sundell, K. L., and Corbin,L.A. (1997). Birth outcomes in pregnant women taking fluoxe-tine. N. Engl. J. Med. 336, 872-873; author reply 873.
26. Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health.
27. Hamilton, M. (1959). The assessment of anxiety states by rating. Br. J. Med. Psychol. 32, 50-55.
28. Hamilton, M. (1960). A rating scale for depression. J. Neurol. Neurosurg. Psychiatr. 23, 56-62.
29. Hebebrand, J., Hofmann, D., Reichelt, R., Schnarr, S., Knapp, M., Propping, P., and Fodisch, H. J. (1988). Early ontogeny of the central benzodi-azepine receptor in human embryos and fetuses. Life Sci. 43, 2127-2136.
30. Herlenius, E., and Lagercrantz, H. (2001). Neurotransmitters and neu-romodulators during early human development. Early Hum. Dev. 65, 21-37.
31. Huizink, A. C., and Buitelaar, J. K. (2000). Prenatal Stress and its Effect on Infant Development. Utrecht: Proefschrift Universiteit Utrecht.
32. Koren, G., and Nickel, C. (2011). Perpetuating fears: bias against the null hypothesis in fetal safety of drugs as expressed in scientific citations. J. Popul. Ther. Clin. Pharmacol. 18, e28^32.
33. Le Strat, Y., Dubertret, C., and Le Foll, B. (2011). Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United States. J. Affect. Disord. 135, 128-138.
34. Marcus, S. M. (2009). Depression during pregnancy: rates, risks and consequences - Motherisk Update 2008. Can. J. Clin. Pharmacol. 16, e15-e22.
35. Martin, S. E., Clements, M. L., and Crnic, K. A. (2002). Maternal emotions during mother-toddler interaction: parenting in affective context. Parent. Sci. Pract. 2, 105-126.
36. Maughan, A., Cicchetti, D., Toth, S. L., and Rogosch, F. A. (2007). Early-occurring maternal depression and maternal negativity in predicting young children's emotion regulation and socioemotional difficulties. J. Abnorm. Child. Psychol. 35, 685-703.
37. McElhatton, P. R. (1994). The effects of benzodiazepine use during pregnancy and lactation. Reprod. Toxicol. 8, 461-475.
38. Misri, S., Burgmann, A., and Kostaras, D. (2000). Are SSRIs safe for pregnant and breastfeeding women? Can. Fam. Physician 46, 626-628, 631-623.
39. Misri, S., Oberlander, T. F., Fairbrother, N., Carter, D., Ryan, D., Kuan, A. J., and Reebye, P. (2004). Relation between prenatal maternal mood and anxiety and neonatal health. Can. J. Psychiatry 49, 684-689.
40. Mulder, E. J., Ververs, F. F., De Heus, R., and Visser, G. H. (2011). Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus. Neuropsychopharma-cology 36, 1961-1971.
41. Nulman, I., Rovet, J., Stewart, D. E., Wolpin, J., Gardner, H. A., Theis, J. G., Kulin, N., and Koren, G. (1997). Neurodevelopment of children exposed in utero to antidepressant drugs. N. Engl. J. Med. 336, 258-262.
42. Oberlander, T. F., Misri, S., Fitzgerald, C. E., Kostaras, X., Rurak, D., and Riggs, W. (2004). Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure. J. Clin. Psychiatry 65, 230-237.
43. Oberlander, T. F., Weinberg, J., Papsdorf, M., Grunau, R., Misri, S., and Devlin, A. M. (2008). Prenatal exposure to maternal depression, neonatal methylation of human glucocor-ticoid receptor gene (NR3C1) and infant cortisol stress responses. Epi-genetics 3, 97-106.
44. O'Connor, T. G., Heron, J., Golding, J., Beveridge,M.,and Glover, V. (2002). Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children. Br. J. Psychiatry 180, 502-508.
45. Papousek,H.,andPapousek, M. (1979). "Early ontogeny of human social interaction: its biological roots and social dimensions," in Human Ethnology: Claims and Limits of a New Discipline, eds M. Von Cranach, K. Foppa, W. Lepennies, and D. Ploog (Cambridge, MA: Cambridge University Press), 456-478.
46. Pastuszak, A., Schick-Boschetto, B., Zuber, C., Feldkamp, M., Pinelli, M., Sihn, S., Donnenfeld, A., Mccor-mack, M., Leen-Mitchell, M., Woodland, C.,et al. (1993). Pregnancy outcome following first-trimester exposure to fluoxetine (Prozac). JAMA 269, 2246-2248.
47. Posner, M. I., and Rothbart, M. K. (2002). Developing mechanisms of self-regulation. Dev. Psychopathol. 12,427-441.
48. Reebye, P. N., Morison, S. J., Panikkar, H., Misri, S., and Grunau, R. E. (2002). Affect expression in pre-natally psychotropic exposed and nonexposed mother-infant dyads. InfantMent. HealthJ. 23,403-416.
49. Sackett, J. C., Weller, R. A., and Weller, E. B. (2009). Selective serotonin reuptake inhibitor use during pregnancy and possible neonatal complications. Curr. Psychiatry Rep. 11, 253-257.
50. Schneider, M. L. (1992). Prenatal stress exposure alters postnatal behavioral expression under conditions of novelty challenge in rhesus monkey infants. Dev. Psychobiol. 25, 529-540.
51. Schore, A. N. (1994). Affect Regulation and the Origin of the Self The Neurobiology of Emotional Development. Hillside, NJ: Lawrence Erl-baum Associates.
52. Simon, G. E., Cunningham, M. L., and Davis, R. L. (2002). Outcomes of prenatal antidepressant exposure. Am. J. Psychiatry 159, 2055-2061.
53. Stern, D. (1995). The Motherhood Constellation: A Unified View of Parent-Infant Psychotherapy. New York: Basic Books.
54. Taveras, E. M., Capra, A. M., Braveman, P. A., Jensvold, N. G., Escobar, G. J., and Lieu, T. A. (2003). Clinician support and psychosocial risk factors associated with breastfeeding discontinuation. Pediatrics 112, 108-115.
55. Tice, D. M., Bratslavsky, E., and Baumeister, R. F. (2001). Emotional distress regulation takes precedence over impulse control: if you feel bad, do it! J. Pers. Soc. Psychol. 80, 53-67.
56. Tronick, E. Z., and Weinberg, M. K. (1997). "Depressed mothers and their infants: failure to form dyadic states of consciousness," in Postpartum Depression and Child Development, eds L. Murray, and P. J. Cooper (New York: Guilford Press), 54-81.
57. Tuccori, M., Testi, A., Antonioli, L., Fornai, M., Montagnani, S., Ghisu, N., Colucci, R., Corona, T., Blandizzi, C., and Del Tacca, M. (2009). Safety concerns associated with the use of serotonin reuptake inhibitors and other serotonergic/noradrenergic antidepressants during pregnancy: a review. Clin. Ther. 31(Pt 1), 1426-1453.
58. Udechuku, A., Nguyen, T., Hill, R., and Szego, K. (2010). Antidepressants in pregnancy: a systematic review. Aust. N. Z. J. Psychiatry 44, 978-996.
59. Van den Bergh, B. R., and Marcoen, A. (2004). High antenatal maternal anxiety is related to ADHD symptoms, externalizing problems, and anxiety in 8-and 9-year-olds. Child Dev. 75, 1085-1097.
60. Way, C. M. (2007). Safety of newer anti-depressants in pregnancy. Pharma-cotherapy 27, 546-552.
61. Weinberg, M. K., Beeghly, M., Olson, K. L., and Tronick, E. (2008). Effects of maternal depression and panic disorder on mother-infant interactive behavior in the face-to-face still-face paradigm. Infant Ment. Health J. 29, 472-491.
62. Welch, E., Fees, B., and Murray, A. D. (2003). Parent-toddler play interaction and its relation to the home environment. Undergrad. Res. J. Human Sci. 2. Available at: http://www.kon.org/urc/welch. html