Non-target screening of Allura Red AC photodegradation products in a beverage through ultra high performance liquid chromatography coupled with hybrid triple quadrupole/linear ion trap mass spectrometry

Food Chemistry

Volumn 136, Issue 2, 2013, Pages 617-623

  Gosetti, Fabio ^a   Chiuminatto, Ugo ^b   Mazzucco, Eleonora ^a   Calabrese, Giorgio ^a   Gennaro, Maria Carla ^a   Marengo, Emilio ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b MDS SCIEX   (Canada)

Author keywords

Allura Red; Degradation products; Hybrid triple quadrupole linear ion trap; Mass spectrometry; Non target screening; Photodegradation; UHPLC

Indexed keywords

ALLURA RED; AMIDE FUNCTIONALITIES; AROMATIC AMINES; ASCORBIC ACIDS; DEGRADATION PRODUCTS; ION TRAPS; ION-TRAP MASS SPECTROMETRY; MS/MS FRAGMENTATION; MULTIPLE REACTION MONITORING; PHOTO-IRRADIATION; PHOTODEGRADATION PRODUCTS; POTENTIAL HAZARDS; SIDE REACTIONS; SIMULATED SUNLIGHT; STRAWBERRY JUICE; TOOL INFORMATION; TRIPLE QUADRUPOLE; UHPLC;

CITRIC ACID; HEALTH HAZARDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONS; MASS SPECTROMETRY; PHOTODEGRADATION; SUGAR (SUCROSE);

DEGRADATION;

ALLURA RED AC; AROMATIC AMIDE; AROMATIC AMINE; ASCORBIC ACID; CHAMOMILE; CITRIC ACID; SUCROSE;

AROMA; ARTICLE; BEVERAGE; CHEMICAL STRUCTURE; ELUTION; FLOWER; FOOD ANALYSIS; FRUIT JUICE; HYBRID; ION MONITORING; ION TRAP MASS SPECTROMETRY; IRRADIATION; PHOTODEGRADATION; SCREENING; STRAWBERRY; TANDEM MASS SPECTROMETRY; TRIPLE QUADRUPOLE LINEAR ION TRAP MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

AZO COMPOUNDS; BEVERAGES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD COLORING AGENTS; FOOD SAFETY; PHOTOLYSIS; TANDEM MASS SPECTROMETRY;

FRAGARIA X ANANASSA;

EID: 84866788768     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.08.019     Document Type: Article

References (32)

1. B. Bateman, J.O. Warner, E. Hutchinson, T. Dean, P. Rowlandson, and C. Gant The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children Archives of Disease in Childhood 89 2004 506 511
2. Chang, P. K. (1994). Color-stable syrup and beverage composition fortified with vitamin C. U.S. Patent 5,336,510.
3. A. Connolly, A. Hearty, A. Nugent, A. McKevitt, E. Boylan, and A. Flynn Pattern of intake of food additives associated with hyperactivity in Irish children and teenagers Food Additives and Contaminants: Part A 27 2010 447 456
4. E. Dinc, A.H. Aktas, D. Baleanu, and O. Ustundag Simultaneous determination of tartrazine and allura red in commercial preparation by chemometric HPLC method Journal of Food and Drug Analysis 14 2006 284 291
5. European Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption.
6. European Food Safety Authority Assessment of the results of the study by McCann et al. (2007) on the effect of some colours and sodium benzoate on children's behaviour The EFSA Journal 660 2008 1 54
7. European Parlament and Council Directive 94/36/EC of 30 June 1994 on colours for use in foodstuffs.
8. B. Fallico, E. Chiappara, E. Arena, and G. Ballistreri Assessment of the exposure to Allura Red colour from the consumption of red juice-based and red soft drinks in Italy Food Additives and Contaminants: Part A 28 2011 1501 1515
9. V. Gianotti, S. Angioi, F. Gosetti, E. Marengo, and M.C. Gennaro Chemometrically assisted development of IP-RP-HPLC and spectrophotometric methods for the identification and determination of synthetic dyes in commercial soft drinks Journal of Liquid Chromatography and Related Technologies 28 2005 923 937
10. Gloria, M. B. A. (2004). Synthetic colorants. In L. M. L. Nollet (Ed.), Handbook of food analysis (2nd ed.; vol. 3, pp. 1513-1542). New York: Marcel Dekker Inc.
11. F. Gosetti, V. Gianotti, S. Angioi, S. Polati, E. Marengo, and M.C. Gennaro Oxidative degradation of food dye E133 Brilliant Blue FCF liquid chromatography-electro spray mass spectrometry identification of the degradation pathway Journal of Chromatography A 1054 2004 379 387
12. F. Gosetti, V. Gianotti, S. Polati, and M.C. Gennaro HPLC-MS degradation study of E110 Sunset Yellow FCF in a commercial beverage Journal of Chromatography A 1090 2005 107 115
13. F. Gosetti, V. Gianotti, E. Mazzucco, S. Polati, and M.C. Gennaro Sunlight induced degradation of E133 in a commercial beverage Dyes and Pigments 74 2007 424 432
14. F. Gosetti, P. Frascarolo, E. Mazzucco, V. Gianotti, M. Bottaro, and M.C. Gennaro Photodegradation of E110 and E122 dyes in a commercial aperitif - A high performance liquid chromatography-diode array-tandem mass spectrometry study Journal of Chromatography A 1202 2008 58 63
15. C. Ji, F. Feng, Z. Chen, and X. Chu Highly sensitive determination of 10 dyes in food with complex matrices using SPE followed by UPLC-DAD-tandem mass spectrometry Journal of Liquid Chromatography and Related Technologies 34 2011 93 105
16. J. Kirschbaum, C. Krause, S. Pfalzgraf, and H. Bruckner Development and evaluation of an HPLC-DAD method for determination of synthetic food colorants Chromatographia 57 2003 115 119
17. M. Kucharska, and J. Grabka A review of chromatographic methods for determination of synthetic food dyes Talanta 80 2010 1045 1051
18. D.M. Marmion Handbook of U.S. colorants: Foods, drugs, cosmetics, and medical devices 3rd ed. 1991 Wiley-Interscience United States
19. D. McCann, A. Barrett, A. Cooper, D. Crumpler, L. Dalen, and K. Grimshaw Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial The Lancet 370 2007 1560 1567
20. T. Mizutani Toxicity of xanthene food dyes by inhibition of human drug-metabolizing enzymes in a noncompetitive manner Journal of Environmental and Public Health 2009 2009 1 9
21. N. Pourreza, S. Rastegarzadeh, and A. Larki Determination of Allura red in food samples after cloud point extraction using mixed micelles Food Chemistry 126 2011 1465 1469
22. Regulation (EC) No. 1333/2008 of the European Parliament and of the Council of 16 December 2008 on food additives.
23. D.W. Schab, and N.H.T. Trinh Do artificial food colors promote hyperactivity in children with hyperactive syndromes? A meta-analysis of double-blind placebo-controlled trials Journal of Developmental and Behavioural Pediatrics 25 2004 423 434
24. C. Shimada, K. Kano, Y.F. Sasaki, I. Sato, and S. Tsudua Differential colon DNA damage induced by azo food additives between rats and mice Journal of Toxicological Sciences 35 2010 547 554
25. S. Shrestha, B.R. Bhattarai, K.-H. Lee, and H. Cho Some of the food color additives are potent inhibitors of human protein tyrosine phosphatases Bulletin of the Korean Chemical Society 27 2006 1567 1571
26. M. Soylak, Y.E. Unsal, and M. Tuzen Spectrophotometric determination of trace levels of allura red in water samples after separation and preconcentration Food and Chemical Toxicology 49 2011 1183 1187
27. D.R. Tennant Screening potential intakes of colour additives used in non-alcoholic beverages Food and Chemical Toxicology 46 2008 1985 1993
28. S. Tsuda, M. Murakami, N. Matsusaka, K. Kano, K. Taniguchi, and Y.F. Sasaki DNA damage induced by red food dyes orally administered to pregnant and male mice Toxicological Sciences 61 2001 92 99
29. Y. Yang, J. Yin, and B. Shao Simultaneous determination of five aluminum lake dyes in chewing gum by HPLC with photodiode array detection Food Additives and Contaminants: Part A 28 2011 1159 1167
30. Y. Zhang, X. Zhang, X. Lu, J. Yang, and K. Wu Multi-wall carbon nanotube film-based electrochemical sensor for rapid detection of Ponceau 4R and Allura Red Food Chemistry 122 2010 909 913
31. D.H. Watson Food chemical safety: Vol. 2. Additives 2001 Woodhead Publishing United Kingdom
32. WHO Food Additives Series 65 (2012). Safety evaluation of certain food additives and contaminants. Geneva: World Health Organization. Available from http://www.fda.gov/ForIndustry/ColorAdditives/ColorAdditiveInventories (accessed 9 May 2012).