Role of c-Myb in the survival of pre b-cell acute lymphoblastic leukemia and leukemogenesis

American Journal of Hematology

Volumn 87, Issue 10, 2012, Pages 969-976

  Sarvaiya, Purvaba J ^a   Schwartz, Jason R ^a   Hernandez, Claudia P ^a   Rodriguez, Paulo C ^a   Vedeckis, Wayne V ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; DOXORUBICIN; DOXYCYCLINE; ETOPOSIDE; MERCAPTOPURINE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN C MYB;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B CELL ACUTE LYMPHOBLASTIC LEUKEMIA; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; HUMAN; IN VITRO STUDY; LEUKEMIA CELL; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DNA REPLICATION; DOXYCYCLINE; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENES, MYB; GENETIC THERAPY; GENETIC VECTORS; HUMANS; LENTIVIRUS; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASM PROTEINS; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRECURSOR CELLS, B-LYMPHOID; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYB; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84866760369     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23283     Document Type: Article

References (55)

1. Pui CH. Recent research advances in childhood acute lymphoblastic leukemia. J Formos Med Assoc 2010; 109: 777-787.
2. Pui C-H, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet 2008; 371: 1030-1043.
3. Gurney JG, Severson RK, Davis S, Robison LL. Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type. Cancer 1995; 75: 2186-2195.
4. Pui CH. Childhood Leukemias. Cambridge: Cambridge University Press; 2006. 21-47 pp.
5. Raimondi SC, Behm FG, Roberson PK, et al. Cytogenetics of pre-B-cell acute lymphoblastic leukemia with emphasis on prognostic implications of the t(1;19). J Clin Oncol 1990; 8: 1380-1388.
6. Oeffinger KC, Eshelman DA, Tomlinson GE, et al. Grading of late effects in young adult survivors of childhood cancer followed in an ambulatory adult setting. Cancer 2000; 88: 1687-1695.
7. Winick NJ, Carroll WL, Hunger SP. Childhood leukemia-New advances and challenges. N Engl J Med 2004; 351: 601-603.
8. Nguyen K, Devidas M, Cheng SC, et al. Factors influencing survival after relapse from acute lymphoblastic leukemia: A Children's Oncology Group study. Leukemia 2008; 22: 2142-2150.
9. Carroll AJ, Crist WM, Parmley RT, et al. Pre-B cell leukemia associated with chromosome translocation 1;19. Blood 1984; 63: 721-724.
10. Hunger SP, Galili N, Carroll AJ, et al. The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias. Blood 1991; 77: 687-693.
11. Crist WM, Carroll AJ, Shuster JJ, et al. Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): A Pediatric Oncology Group study. Blood 1990; 76: 117-122.
12. Klempnauer KH, Gonda TJ, Bishop JM. Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene. Cell 1982; 31: 453-463.
13. Leprince D, Gegonne A, Coll J, et al. A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature 1983; 306: 395-397.
14. Mucenski ML, McLain K, Kier AB, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991; 65: 677-689.
15. Emambokus N, Vegiopoulos A, Harman B, et al. Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. EMBO J 2003; 22: 4478-4488.
16. Sandberg ML, Sutton SE, Pletcher MT, et al. c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation. Dev Cell 2005; 8: 153-166.
17. Sakamoto H, Dai G, Tsujino K, et al. Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development. Blood 2006; 108: 896-903.
18. Shen-Ong GL, Potter M, Mushinski JF, et al. Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas. Science 1984; 226: 1077-1080.
19. Hwang HC, Martins CP, Bronkhorst Y, et al. Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis. Proc Natl Acad Sci USA 2002; 99: 11293-11298.
20. Kanter MR, Smith RE, Hayward WS. Rapid induction of B-cell lymphomas: Insertional activation of c-myb by avian leukosis virus. J Virol 1988; 62: 1423-1432.
21. Kim R, Trubetskoy A, Suzuki T, et al. Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas. J Virol 2003; 77: 2056-2062.
22. Wolff L. Myb-induced transformation. Crit Rev Oncog 1996; 7: 245-260.
23. Harper ME, Franchini G, Love J, et al. Chromosomal sublocalization of human c-myb and c-fes cellular onc genes. Nature 1983; 304: 169-171.
24. Schwartz JR, Sarvaiya PJ, Vedeckis WV. Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia. Mol Cell Endocrinol 2010; 320: 76-86.
25. Pedersen KB, Vedeckis WV. Quantification and glucocorticoid regulation of glucocorticoid receptor transcripts in two human leukemic cell lines. Biochemistry 2003; 42: 10978-10990.
26. Geng CD, Vedeckis WV. A new, lineage specific, autoup-regulation mechanism for human glucocorticoid receptor gene expression in 697 pre-B-acute lymphoblastic leukemia cells. Mol Endocrinol 2011; 25: 44-57.
27. Zabaleta J, McGee DJ, Zea AH, et al. Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta). J Immunol 2004; 173: 586-593.
28. Duriez PJ, Shah GM. Cleavage of poly(ADP-ribose) polymerase: A sensitive parameter to study cell death. Biochem Cell Biol 1997; 75: 337-349.
29. Joashi UC, Greenwood K, Taylor DL, et al. Poly(ADP ribose) polymerase cleavage precedes neuronal death in the hippocampus and cerebellum following injury to the developing rat forebrain. Eur J Neurosci 1999; 11: 91-100.
30. Shah GM, Shah RG, Poirier GG. Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells. Biochem Biophys Res Commun 1996; 229: 838-844.
31. Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, et al. Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis. J Biol Chem 1998; 273: 13703-13712.
32. Nakagoshi H, Kanei-Ishii C, Sawazaki T, et al. Transcriptional activation of the c-myc gene by the c-myb and B-myb gene products. Oncogene 1992; 7: 1233-1240.
33. Frampton J, Ramqvist T, Graf T. v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells. Genes Dev 1996; 10: 2720-2731.
34. Thompson MA, Rosenthal MA, Ellis SL, et al. c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression. Cancer Res 1998; 58: 5168-5175.
35. Corona G, Casetta B, Sandron S, et al. Rapid and sensitive analysis of vincristine in human plasma using on-line extraction combined with liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2008; 22: 519-525.
36. DiFrancesco R, Griggs JJ, Donnelly J, DiCenzo R. Simultaneous analysis of cyclophosphamide, doxorubicin and doxorubicinol by liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2007; 852: 545-553.
37. Estlin EJ. Continuing therapy for childhood acute lymphoblastic leukaemia: Clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine. Cancer Treat Rev 2001; 27: 351-363.
38. Pein F, Pinkerton R, Berthaud P, et al. Dose finding study of oral PSC 833 combined with weekly intravenous etoposide in children with relapsed or refractory solid tumours. Eur J Cancer 2007; 43: 2074-2081.
39. Linger RM, DeRyckere D, Brandao L, et al Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia. Blood 2009; 114: 2678-2687.
40. Cobaleda C, Sanchez-Garcia I. B-cell acute lymphoblastic leukaemia: Towards understanding its cellular origin. Bioessays 2009; 31: 600-609.
41. Anfossi G, Gewirtz AM, Calabretta B. An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci USA 1989; 86: 3379-3383.
42. Calabretta B, Sims RB, Valtieri M, et al. Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: An in vitro study relevant to bone marrow purging. Proc Natl Acad Sci USA 1991; 88: 2351-2355.
43. Clappier E, Cuccuini W, Kalota A, et al. The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children. Blood 2007; 110: 1251-1261.
44. Lahortiga I, De Keersmaecker K, Van Vlierberghe P, et al. Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia. Nat Genet 2007; 39: 593-595.
45. Gewirtz AM, Anfossi G, Venturelli D, et al. G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science 1989; 245: 180-183.
46. Nakata Y, Shetzline S, Sakashita C, et al. c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression. Mol Cell Biol 2007; 27: 2048-2058.
47. Thomas MD, Kremer CS, Ravichandran KS, et al. c-Myb is critical for B cell development and maintenance of follicular B cells. Immunity 2005; 23: 275-286.
48. Kauraniemi P, Hedenfalk I, Persson K, et al. MYB oncogene amplification in hereditary BRCA1 breast cancer. Cancer Res 2000; 60: 5323-5328.
49. Wallrapp C, Muller-Pillasch F, Solinas-Toldo S, et al. Characterization of a high copy number amplification at 6q24 in pancreatic cancer identifies c-myb as a candidate oncogene. Cancer Res 1997; 57: 3135-3139.
50. Alitalo K, Winqvist R, Lin CC, et al. Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma. Proc Natl Acad Sci USA 1984; 81: 4534-4538.
51. Welter C, Henn W, Theisinger B, et al. The cellular myb oncogene is amplified, rearranged and activated in human glioblastoma cell lines. Cancer Lett 1990; 52: 57-62.
52. Zabel BU, Naylor SL, Grzeschik KH, Sakaguchi AY. Regional assignment of human protooncogene c-myb to 6q21----qter. Somat Cell Mol Genet 1984; 10: 105-108.
53. Barletta C, Pelicci PG, Kenyon LC, et al. Relationship between the c-myb locus and the 6q-chromosomal aberration in leukemias and lymphomas. Science 1987; 235: 1064-1067.
54. Dasgupta P, Reddy EP. Identification of alternatively spliced transcripts for human c-myb: Molecular cloning and sequence analysis of human c-myb exon 9A sequences. Oncogene 1989; 4: 1419-1423.
55. Waldron T, De Dominici M, Soliera AR, et al. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells. Leukemia 2011; 26: 644-653.