Association study of NOS1 gene polymorphisms and schizophrenia

Chinese Journal of Medical Genetics

Volumn 29, Issue 4, 2012, Pages 459-463

  Wang, Jia ^a   Ma, Xiao Hong ^a,b   Xiang, Bo ^a   Wu, Jun Yao ^a   Wang, Ying Cheng ^a   Deng, Wei ^b   Li, Ming Li ^b   Wang, Qiang ^b   He, Zong Ling ^b   Li, Tao ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Association study; Nitric oxide synthase 1; Schizophrenia; Single nucleotide polymorphisms

Indexed keywords

NEURONAL NITRIC OXIDE SYNTHASE;

ARTICLE; CHINESE; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; NITRIC OXIDE SYNTHASE TYPE I; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84866759462     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1003-9406.2012.04.018     Document Type: Article

References (19)

1. Kirov G, O'Donovan MC, Owen MJ. Finding schizophrenia genes. J Clin Invest,2005,115:1440-1448. (Pubitemid 40814648)
2. Saha S, Chant D, Welham J, et al. A systematic review of the prevalence of schizophrenia. PloS Med,2005,2:413-433.
3. Cardno AG, Gottesman II. Twin studies of schizophrenia: from bow-and-arrow concordances to star wars mx and functional genomics. Am J Med Genet,2000,97:12-17. (Pubitemid 30257322)
4. Walsh T, McClellan JM, McCarthy SE, et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science,2008,320:539-543. (Pubitemid 351590668)
5. Hara H, Waeber C, Huang PL, et al. Brain distribution of nitric oxide synthase in neuronal or endothelial nitric oxide synthase mutant mice using [H-3]L-N-G-nitro-arginine autoradiography. Neuroscience,1996,75:881-890. (Pubitemid 26377057)
6. Shinkai T, Ohmori O, Hori H, et al. Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia. Mol Psychiatry,2002,7:560- 563.
7. Liou YJ, Tsai SJ, Hong CJ, et al. Association analysis for the CA repeat polymorphism of the neuronal nitric oxide synthase (NOS1) gene and schizophrenia. Schizophr Res,2003,65:57-59.
8. Contestabile A. Roles of NMDA receptor activity and nitric oxide production in brain development. Brain Res Brain Res Rev,2000,32:476-509. (Pubitemid 30171317)
9. Gibbs SM. Regulation of neuronal proliferation and differentiation by nitric oxide. Mol Neurobiol,2003,27:107-120. (Pubitemid 36724515)
10. Brenman JE, Bredt DS. Synaptic signaling by nitric oxide. Curr Opin in Neurobiol,1997,7:374-378. (Pubitemid 27321029)
11. Lorrain DS, Hull EM. Nitric oxide increases dopamine and serotonin release in the medial preoptic area. Neuroreport,1993,5:87-89. (Pubitemid 23330829)
12. Yilmaz N, Herken H, Cicek HK, et al. Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia. Med Princ Pract,2007,16:137-141.
13. Lauer M, Johannes S, Fritzen S, et al. Morphological abnormalities in nitric-oxide-synthase-positive striatal Interneurons of schizophrenic patients. Neuropsychobiology,2005,52:111-117. (Pubitemid 41318187)
14. Fritzen S, Lauer M, Schmitt A, et al. NO synthase-positive striatal interneurons are decreased in schizophrenia. Eur Neuropsychopharmacol,2007,17: 595-599. (Pubitemid 47068931)
15. Reif A, Herterich S, Strobel A, et al. A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function. Mol Psychiatry,2006,11:286-300.
16. Tang W, Huang K, Tang R, et al. Evidence for association between the 5′ flank of the NOS1 gene and schizophrenia in the Chinese population. Int J Neuropsychopharmacol,2008,11:1063-1071.
17. Okumura T, Okochi T, Kishi T, et al. No association between polymorphisms of neuronal oxide synthase 1 gene (NOS1) and schizophrenia in a Japanese population. Neuromolecular Med,2009,11:123-127.
18. Cui H, Nishiguchi N, Yanagi M, et al. A putative cis-acting polymorphism in the NOS1 gene is associated with schizophrenia and NOS1 immunoreactivity in the postmortem brain. Schizophr Res,2010,121:172-178.
19. Donohoe G, Walters J, Morris DW, et al. Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects. Arch Gen Psychiatry,2009,66:1045-1054.