A case study in converting disposable process scouting devices into disposable bioreactors as a future bioprocessing tool

Biotechnology and Bioengineering

Volumn 109, Issue 11, 2012, Pages 2790-2797

  Vallejos, José R ^a,c   Uplekar, Shaunak ^a   da Silva, João F ^a   Brorson, Kurt A ^b   Moreira, Antonio R ^a   Rao, Govind ^a,d  

^a University of Marylandw Baltimore County   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c DSM RESOLVE   (Netherlands)

^d Center for Advanced Sensor Technology (CAST)   (United States)

Author keywords

Disposable bioreactors; Mass transfer; Mixing; Optical sensors; Seed train; Spinner flasks

Indexed keywords

BIOPROCESSING; CRITICAL CELLS; DO CONTROL; ENVIRONMENTAL CONDITIONS; HISTORICAL DATA; HYBRIDOMA CELLS; MASS TRANSFER STUDIES; MIXING TIME; NOVEL DEVICES; PRODUCTION SCALE; SPINNER FLASKS; STIRRED BIOREACTORS; VIABLE CELLS;

BIOCONVERSION; BOTTLES; CELL CULTURE; DIGITAL STORAGE; MASS TRANSFER; MIXING; OPTICAL SENSORS;

BIOREACTORS;

DISSOLVED OXYGEN;

ARTICLE; BIOREACTOR; CANCER CELL CULTURE; CELL CULTURE; CELL DENSITY; CONTROLLED STUDY; DISPOSABLE EQUIPMENT; HUMAN; HUMAN CELL; LABORATORY; OPTICAL BIOSENSOR; PH;

ANIMALS; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA; DISPOSABLE EQUIPMENT; MICE; OXYGEN; PROTEINS; TIME FACTORS;

EID: 84866756841     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24541     Document Type: Article

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