Integrating a 250 mL-spinner flask with other stirred bench-scale cell culture devices: A mass transfer perspective

Biotechnology Progress

Volumn 27, Issue 3, 2011, Pages 803-810

  Vallejos, Jose R ^a   Brorson, Kurt A ^b   Moreira, Antonio R ^a   Rao, Govind ^a  

^a University of Marylandw Baltimore County   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Bioprocess development; Mass transfer; Minibioreactors; Scale up; Spinner flasks

Indexed keywords

AGITATION SPEED; BIOMANUFACTURING; BIOPROCESS DEVELOPMENT; CELL BIOLOGY; COMPLEX TASK; MINIBIOREACTORS; MIXING TIME; PHYSICAL PARAMETERS; PROCESS UNDERSTANDING; PRODUCT QUALITY; SCALE-UP; SPINNER FLASKS; TRANSFER CAPABILITY; VOLUMETRIC MASS TRANSFER COEFFICIENT;

BOTTLES; CARBON DIOXIDE; CELL CULTURE; PROCESS MONITORING; VOLUMETRIC ANALYSIS;

MASS TRANSFER;

ARTICLE; BIOREACTOR; CULTURE TECHNIQUE; DRUG INDUSTRY; INSTRUMENTATION; METHODOLOGY;

BIOREACTORS; CELL CULTURE TECHNIQUES; DRUG INDUSTRY;

EID: 79958249917     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.578     Document Type: Article

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