Independent transcriptional reprogramming and apoptosis induction by cisplatin

Cell Cycle

Volumn 11, Issue 18, 2012, Pages 3472-3480

  Galluzzi, Lorenzo ^a,b   Vitale, Ilio ^b,c,d   Senovilla, Laura ^b,c,d   Eisenberg, Tobias ^e   Carmona Gutierrez, Didac ^e   Vacchelli, Erika ^b,c,d   Robert, Thomas ^b   Ripoche, Hugues ^b,f   Jägemann, Nora ^g   Paccard, Caroline ^h,i,j   Servant, Nicolas ^h,i,j   Hupé, Philippe ^f,h,i,j   Lazar, Vladimir ^b   Dessen, Philippe ^b,k   Barillot, Emmanuel ^h,i,j   Zischka, Hans ^g   Madeo, Frank ^e   Kroemer, Guido ^a,b,c,l,m  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c Institut Gustave Roussy   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e UNIVERSITY OF GRAZ   (Austria)

^f CNRS   (France)

^g INSTITUTE OF EPIDEMIOLOGY   (Germany)

^h INSTITUT CURIE   (France)

ⁱ INSERM U900   (France)

^j PSL RESEARCH UNIVERSITY   (France)

^k INSERM   (France)

^l HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^m CENTRE DE RECHERCHE DES CORDELIERS   (France)

more..

Author keywords

Autophagy; Bongkrekic acid; Cyclosporine A; Glutathione; Large amplitude swelling; N acetyl cysteine

Indexed keywords

CADMIUM DERIVATIVE; CADMIUM DICHLORIDE; CERAMIDE; CISPLATIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG NON SMALL CELL CANCER; MALE; MITOCHONDRION SWELLING; MOLECULAR GENETICS; NONHUMAN; PURIFICATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL REPROGRAMMING; YEAST;

EID: 84866753909     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.21789     Document Type: Article

References (44)

1. Kelland L. The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer 2007; 7:573-84; PMID:17625587; http://dx.doi.org/10.1038/nrc2167.
2. Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Pro-senescence therapy for cancer treatment. Nat Rev Cancer 2011; 11:503-11; PMID:21701512; http:// dx.doi.org/10.1038/nrc3057.
3. Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev 2007; 87:99-163; PMID:17237344; http://dx.doi. org/10.1152/physrev.00013.2006.
4. Mandic A, Hansson J, Linder S, Shoshan MC. Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling. J Biol Chem 2003; 278:9100-6; PMID:12509415; http://dx.doi. org/10.1074/jbc.M210284200.
5. Berndtsson M, Hägg M, Panaretakis T, Havelka AM, Shoshan MC, Linder S. Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA. Int J Cancer 2007; 120:175-80; PMID:17044026; http://dx.doi. org/10.1002/ijc.22132.
6. Gonzalez VM, Fuertes MA, Alonso C, Perez JM. Is cisplatin-induced cell death always produced by apoptosis? Mol Pharmacol 2001; 59:657-63; PMID:11259608.
7. Tajeddine N, Galluzzi L, Kepp O, Hangen E, Morselli E, Senovilla L, et al. Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death. Oncogene 2008; 27:4221-32; PMID:18362892; http://dx.doi.org/10.1038/onc. 2008.63.
8. Castedo M, Coquelle A, Vivet S, Vitale I, Kauffmann A, Dessen P, et al. Apoptosis regulation in tetraploid cancer cells. EMBO J 2006; 25:2584-95; PMID:16675948; http://dx.doi.org/10.1038/sj.emboj.7601127.
9. Winter C, Albers P. Testicular germ cell tumors: pathogenesis, diagnosis and treatment. Nat Rev Endocrinol 2011; 7:43-53; PMID:21116298; http://dx.doi. org/10.1038/nrendo.2010.196.
10. Galluzzi L, Senovilla L, Vitale I, Michels J, Martins I, Kepp O, et al. Molecular mechanisms of cisplatin resistance. Oncogene 2012; 31:1869-83; PMID:21892204; http://dx.doi.org/10.1038/onc.2011.384.
11. Köberle B, Tomicic MT, Usanova S, Kaina B. Cisplatin resistance: preclinical findings and clinical implications. Biochim Biophys Acta 2010; 1806:172-82; PMID:20647037.
12. Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22:7265-79; PMID:14576837; http://dx.doi.org/10.1038/ sj.onc.1206933.
13. Beers MH. Lung carcinoma. In: Porter RS, Jones TV, eds. The Merck manual of diagnosis and therapy. Rahway: Merck & Co., Inc., 2008:2992.
14. Jemal A, Thun MJ, Ries LA, Howe HL, Weir HK, Center MM, et al. Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst 2008; 100:1672-94; PMID:19033571; http://dx.doi.org/10.1093/jnci/djn389.
15. Brenner C, Grimm S. The permeability transition pore complex in cancer cell death. Oncogene 2006; 25:4744-56; PMID:16892087; http://dx.doi.org/10.1038/ sj.onc.1209609.
16. Rippo MR, Malisan F, Ravagnan L, Tomassini B, Condo I, Costantini P, et al. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. FASEB J 2000; 14:2047-54; PMID:11023989; http://dx.doi.org/10.1096/fj.99- 1028com.
17. Jimi S, Uchiyama M, Takaki A, Suzumiya J, Hara S. Mechanisms of cell death induced by cadmium and arsenic. Ann NY Acad Sci 2004; 1011:325-31; PMID:15126309; http://dx.doi.org/10.1196/annals.1293.032.
18. Novgorodov SA, Gudz TI, Milgrom YM, Brierley GP. The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. J Biol Chem 1992; 267:16274-82; PMID:1644813.
19. Lê Quôc K, Lê Quôc D. Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site. Arch Biochem Biophys 1988; 265:249-57; PMID:2844116; http://dx.doi.org/10.1016/0003- 9861(88)90125-7.
20. Galluzzi L, Morselli E, Vitale I, Kepp O, Senovilla L, Criollo A, et al. miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res 2010; 70:1793-803; PMID:20145152; http://dx.doi.org/10.1158/0008-5472.CAN-09- 3112.
21. Kepp O, Galluzzi L, Lipinski M, Yuan J, Kroemer G. Cell death assays for drug discovery. Nat Rev Drug Discov 2011; 10:221-37; PMID:21358741; http://dx.doi.org/10.1038/nrd3373.
22. th, Faden AI. Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. Mol Cell Neurosci 2003; 22:365-82; PMID:12691738; http://dx.doi.org/10.1016/S1044-7431(02)00028-3.
23. Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 2009; 16:1093-107; PMID:19373242; http://dx.doi.org/10.1038/cdd.2009.44.
24. Galluzzi L, Zamzami N, de La Motte Rouge T, Lemaire C, Brenner C, Kroemer G. Methods for the assessment of mitochondrial membrane permeabilization in apoptosis. Apoptosis 2007; 12:803-13; PMID:17294081; http://dx.doi.org/10.1007/ s10495-007-0720-1.
25. Galluzzi L, Vitale I, Senovilla L, Olaussen KA, Pinna G, Eisenberg T, et al. Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer. Cell Rep 2012; In press; PMID:22854025; http://dx.doi.org/10.1016/j.celrep.2012.06.017.
26. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al.; The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat Genet 2000; 25:25-9; PMID:10802651; http://dx.doi.org/10.1038/ 75556.
27. Kanehisa M. A database for post-genome analysis. Trends Genet 1997; 13:375-6; PMID:9287494; http://dx.doi.org/10.1016/S0168-9525(97)01223-7.
28. Alexa A, Rahnenführer J, Lengauer T. Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinformatics 2006; 22:1600-7; PMID:16606683; http://dx.doi.org/10.1093/ bioinformatics/btl140.
29. Pauleau AL, Galluzzi L, Scholz SR, Larochette N, Kepp O, Kroemer G. Unexpected role of the phosphate carrier in mitochondrial fragmentation. Cell Death Differ 2008; 15:616-8; PMID:18174900; http://dx.doi.org/10.1038/sj.cdd. 4402295.
30. Poncet D, Pauleau AL, Szabadkai G, Vozza A, Scholz SR, Le Bras M, et al. Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA. J Cell Biol 2006; 174:985-96; PMID:16982800; http://dx.doi.org/10.1083/ jcb.200604069.
31. Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, et al. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J 2011; 30:2779-92; PMID:21673659; http://dx.doi.org/10.1038/ emboj.2011.197.
32. Morigasaki S, Shimada K, Ikner A, Yanagida M, Shiozaki K. Glycolytic enzyme GAPDH promotes peroxide stress signaling through multistep phosphorelay to a MAPK cascade. Mol Cell 2008; 30:108-13; PMID:18406331; http://dx.doi.org/ 10.1016/j.molcel.2008.01.017.
33. Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, Larochette N, et al. GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene 2007; 26:2606-20; PMID:17072346; http://dx.doi.org/ 10.1038/sj.onc.1210074.
34. Zhivotovsky B, Galluzzi L, Kepp O, Kroemer G. Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery. Cell Death Differ 2009; 16:1419-25; PMID:19696789; http://dx.doi.org/10.1038/ cdd.2009.118.
35. Futai E, Maeda T, Sorimachi H, Kitamoto K, Ishiura S, Suzuki K. The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation. Mol Gen Genet 1999; 260:559-68; PMID:9928935; http://dx.doi.org/10.1007/s004380050929.
36. Kroemer G, Jäättelä M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5:886-97; PMID:16239905; http://dx.doi.org/10.1038/nrc1738.
37. Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 2010; 11:700-14; PMID:20823910; http://dx.doi.org/10.1038/nrm2970.
38. Cheng EH, Sheiko TV, Fisher JK, Craigen WJ, Korsmeyer SJ. VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science 2003; 301:513-7; PMID:12881569; http://dx.doi.org/10.1126/science.1083995.
39. de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, et al. A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res 2007; 67:6253-62; PMID:17616683; http://dx.doi.org/10.1158/0008-5472.CAN-07- 0538.
40. Boehrer S, Adès L, Braun T, Galluzzi L, Grosjean J, Fabre C, et al. Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study. Blood 2008; 111:2170-80; PMID:17925489; http://dx.doi.org/10. 1182/blood-2007-07-100362.
41. Madeo F, Herker E, Maldener C, Wissing S, Lächelt S, Herlan M, et al. A caspase-related protease regulates apoptosis in yeast. Mol Cell 2002; 9:911-7; PMID:11983181; http://dx.doi.org/10.1016/S1097-2765(02)00501-4.
42. Zischka H, Larochette N, Hoffmann F, Hamöller D, Jägemann N, Lichtmannegger J, et al. Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. Anal Chem 2008; 80:5051-8; PMID:18510346; http://dx.doi.org/10.1021/ac800173r.
43. Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis 2010; 1:e10; PMID:21364612; http://dx.doi.org/10.1038/cddis.2009.8.
44. Vitale I, Senovilla L, Jemaà M, Michaud M, Galluzzi L, Kepp O, et al. Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. EMBO J 2010; 29:1272-84; PMID:20186124; http://dx.doi.org/10.1038/emboj. 2010.11.