Filamin A is a regulator of blood-testis barrier assembly during postnatal development in the rat testis

Endocrinology

Volumn 153, Issue 10, 2012, Pages 5023-5035

  Su, Wenhui ^a,b   Mruk, Dolores D ^a   Lie, Pearl P Y ^a   Lui, Wing Yee ^c   Cheng, C Yan ^a  

^a POPULATION COUNCIL   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FILAMIN A; SMALL INTERFERING RNA; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; BLOOD TESTIS BARRIER; CYTOSKELETON; DOWN REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GERM CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROENVIRONMENT; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; SERTOLI CELL; TESTIS DEVELOPMENT; TIGHT JUNCTION;

ANIMALS; BLOOD-TESTIS BARRIER; CELLS, CULTURED; CONTRACTILE PROTEINS; MALE; MICROFILAMENT PROTEINS; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; SERTOLI CELLS; TESTIS; TIGHT JUNCTIONS;

EID: 84866753015     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1286     Document Type: Article

References (55)

1. Clermont Y, Perry B 1957 Quantitative study of the cell population of the seminiferous tubules in immature rats. J Anat 100:241-267
2. Bergmann M, Dierichs R 1983 Postnatal formation of the bloodtestis barrier in the rat with special reference to the initiation of meiosis. Anat Embryol 168:269-275 (Pubitemid 14245306)
3. Vitale R, Fawcett DW, Dym M 1973 The normal development of the blood-testis barrier and the effects of clomiphene and estrogen treatment. Anat Rec 176:331-344
4. Mok KW, Mruk DD, Lee WM, Cheng CY 2011 A study to assess the assembly of a functional blood-testis barrier in developing rat testes. Spermatogenesis 1:270-280
5. Toyama Y, Ohkawa M, Oku R, Maekawa M, Yuasa S 2001 Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat. J Androl 22:413-423 (Pubitemid 32327971)
6. Cheng CY, Lie PP, Wong EW, Mruk DD, Silvestrini B 2011 Adjudin disrupts spermatogenesis via the action of some unlikely partners: Eps8, Arp2/3 complex, drebrin E, PAR6 and 14-3-3. Spermatogenesis 1:291-297
7. Cheng CY, Mruk D, Silvestrini B, Bonanomi M, Wong CH, Siu MK, Lee NP, Lui WY, Mo MY 2005 AF-2364 [1-(2,4-dichlorobenzyl)- 1H-indazole-3-carbohydrazide] is a potential male contraceptive: A review of recent data. Contraception 72:251-261 (Pubitemid 41338106)
8. Mok KW, Mruk DD, Lee WM, Cheng CY 2012 Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility. Int J Androl 35:86-101
9. Cheng CY, Mruk DD 2012 The blood-testis barrier and its implication in male contraception. Pharmacol Rev 64:16-64
10. Nah WH, Lee JE, Park HJ, Park NC, Gye MC 2011 Claudin-11 expression increased in spermatogenic defect in human testes. Fertil Steril 95:385-388
11. Cheng CY, Mruk DD 2010 A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol 6:380-395
12. Lie PP, Chan AY, Mruk DD, Lee WM, Cheng CY 2010 Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis. Proc Natl Acad Sci USA 107:11411-11416
13. Lie PP, Mruk DD, Lee WM, Cheng CY 2009 Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium. FASEB J 23:2555-2567
14. Li MW, Xiao X, Mruk DD, Lam YL, Lee WM, Lui WY, Bonanomi M, Silvestrini B, Cheng CY 2011 Actin binding protein drebrin E is involved in junction dynamics during spermatogenesis. Spermatogenesis 1:123-136
15. Zhou AX, Hartwig JH, Akyürek LM 2010 Filamins in cell signaling, transcription and organ development. Trends Cell Biol 20:113-123
16. Nakamura F, Stossel TP, Hartwig JH 2011 The filamins. Organizers of cell structure and function. Cell Adh Migr 5:160-169
17. Aravindan GR, Pineau CP, Bardin CW, Cheng CY 1996 Ability of trypsin in mimicking germ cell factors that affect Sertoli cell secretory function. J Cell Physiol 168:123-133 (Pubitemid 26233440)
18. Pineau C, Syed V, Bardin CW, Jégou B, Cheng CY 1993 Germ cell conditioned medium contains multiple factors that modulate the secretion of testin, clusterin, and transferrin by Sertoli cells. J Androl 14:87-98 (Pubitemid 23264403)
19. Mruk DD, Cheng CY 2011 An in vitro system to study Sertoli cell blood-testis barrier dynamics. Methods Mol Biol 763:237-252
20. Wong CC, Chung SS, Grima J, Zhu LJ, Mruk D, Lee WM, Cheng CY 2000 Changes in the expression of junctional and nonjunctional complex component genes when inter-Sertoli tight junctions are formed in vitro. J Androl 21:227-237 (Pubitemid 30123704)
21. Galdieri M, Ziparo E, Palombi F, Russo MA, Stefanini M 1981 Pure Sertoli cell cultures: a new model for the study of somatic-germ cell interactions. J Androl 5:249-259
22. Lee NP, Mruk D, Lee WM, Cheng CY 2003 Is the cadherin/catenin complex a functional unit of cell-cell-actin-based adherens junctions (AJ) in the rat testis? Biol Reprod 68:489-508 (Pubitemid 36139314)
23. Orth JM 1982 Proliferation of Sertoli cells in fetal and postnatal rats: a quantitative autoradiographic study. Anat Rec 203:485-492 (Pubitemid 12048185)
24. 2-macroglobulin, and testins: biosynthesis and differential regulation by germ cells. Mol Cell Endocrinol 89:127-140
25. Lui WY, Lee WM, Cheng CY 2001 Transforming growth factor-β3 perturbs the inter-Sertoli tight junction permeability barrier in vitro possibly mediated via its effects on occludin, zonula occludens-1, and claudin-11. Endocrinology 142:1865-1877 (Pubitemid 32405944)
26. Grima J, Wong CC, Zhu LJ, Zong SD, Cheng CY 1998 Testin secreted by Sertoli cells is associated with the cell surface, and its expression correlates with the disruption of Sertoli-germ cell junctions but not the inter-Sertoli tight junction. J Biol Chem 273:21040-21053 (Pubitemid 28385389)
27. Siu MK, Wong CH, Lee WM, Cheng CY 2005 Sertoli-germ cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases. J Biol Chem 280:25029-25047 (Pubitemid 40934595)
28. Lee NP, Cheng CY 2003 Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3′,5′-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study. Endocrinology 144:3114-3129 (Pubitemid 36819914)
29. Li MW, Mruk DD, Lee WM, Cheng CY 2009 Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? Int J Biochem Cell Biol 41:2302-2314
30. Lie PP, Cheng CY, Mruk DD 2010 Crosstalk between desmoglein-2/ desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ ZO-1 protein complexes, regulates blood-testis barrier dynamics. Int J Biochem Cell Biol 42:975-986
31. Janecki A, Jakubowiak A, Steinberger A 1991 Effects of cyclic AMP and phorbol ester on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment culture. Mol Cell Endocrinol 82:61-69
32. Janecki A, Jakubowiak A, Steinberger A 1991 Regulation of transepithelial electrical resistance in two-compartment Sertoli cell cultures: in vitro model of the blood-testis barrier. Endocrinology 129:1489-1496
33. Janecki A, Jakubowiak A, Steinberger A 1992 Effect of cadmium chloride on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment cultures: a new model for toxicological investigations of the "blood-testis" barrier in vitro. Toxicol Appl Pharmacol 112:51-57
34. Byers SW, Hadley MA, Djakiew D, Dym M 1986 Growth and characterization of epididymal epithelial cells and Sertoli cells in dual environment culture chambers. J Androl 7:59-68 (Pubitemid 16132311)
35. Lui WY, Lee WM, Cheng CY 2003 Transforming growth factor-β3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway. Biol Reprod 68:1597-1612 (Pubitemid 36519763)
36. Chung NP, Cheng CY 2001 Is cadmium chloride-induced inter-Sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events of junction disassembly during spermatogenesis in the rat testis? Endocrinology 142:1878-1888 (Pubitemid 32405945)
37. Siu MK, Lee WM, Cheng CY 2003 The interplay of collagen IV, tumor necrosis factor-α, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloprotease-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology 144:371-387 (Pubitemid 36076127)
38. Yan HH, Mruk DD, Wong EW, Lee WM, Cheng CY 2008 An autocrine axis in the testis that coordinates spermiation and bloodtestis barrier restructuring during spermatogenesis. Proc Natl Acad Sci USA 105:8950-8955
39. Mruk DD, Cheng CY 2011 Enhanced chemiluminescence (ECL) for routine immunoblotting. An inexpensive alternative to commercially available kits. Spermatogenesis 1:121-122
40. Li MW, Xia W, Mruk DD, Wang CQ, Yan HH, Siu MK, Lui WY, Lee WM, Cheng CY 2006 TNFα reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes. J Endocrinol 190:313-329 (Pubitemid 44288369)
41. Wong CH, Mruk DD, Lui WY, Cheng CY 2004 Regulation of blood-testis barrier dynamics: an in vivo study. J Cell Sci 117:783-798 (Pubitemid 38263222)
42. Setchell BP, Waites GMH 1970 Changes in the permeability of the testicular capillaries and of the "blood-testis barrier" after injection of cadmium chloride in the rat. J Endocrinol 47:81-86
43. Shinohara T, Avarbock MR, Brinster RL 1999 β1- and α6-integrin are surface markers on mouse spermatogonial stem cells. Proc Natl Acad Sci USA 96:5504-5509 (Pubitemid 29234647)
44. Palombi F, Salanova M, Tarone G, Farini D, Stefanini M 1992 Distribution of β1 integrin subunit in rat seminiferous epithelium. Biol Reprod 47:1173-1182
45. Kim H, Nakamura F, Lee W, Shifrin Y, Arora P, McCulloch CA 2010 Filamin A is required for vimentin-mediated cell adhesion and spreading. Am J Physiol Cell Physiol 298:C221-C236
46. Kim H, Nakamura F, Lee W, Hong C, Pérez-Sala D, McCulloch CA 2010 Regulation of cell adhesion to collagen via β1 integrins is dependent on interactions of filamin A with vimentin and protein kinase c epsilon. Exp Cell Res 316:1829-1844
47. Li MW, Mruk DD, Lee WM, Cheng CY 2009 Cytokines and junction restructuring events during spermatogenesis in the testis: an emerging concept of regulation. Cytokine Growth Factor Rev 20:329-338
48. Cheng CY, Mruk DD 2011 Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3. Biochem J 435:553-562
49. Seo MD, Seok SH, Im H, Kwon AR, Lee SJ, Kim HR, Cho Y, Park D, Lee BJ 2009 Crystal structure of the dimerization domain of human filamin A. Proteins 75:258-263
50. Griffiths GS, Grundl M, Allen 3rd JS, Matter ML 2011 R-Ras intercts with filamin A to maintain endothelial barrier function. J Cell Physiol 226:2287-2296
51. Kim H, McCulloch CA 2011 Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion. FEBS Lett 585:18-22
52. Cheng CY, Mruk DD 2011 Actin binding proteins and spermatogenesis. Some unexpected findings. Spermatogenesis 1:99-104
53. Yan HH, Mruk DD, Lee WM, Cheng CY 2008 Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J 22:1945-1959 (Pubitemid 351811471)
54. Su L, Mruk DD, Lee WM, Cheng CY 2010 Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier. Exp Cell Res 316:2945-2960
55. Whitmarsh AJ 2009 Filamin B: a scaffold for interferon signalling. EMBO Rep 10:349-351