Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 3, 2012, Pages 800-806

  Lim, Yiting ^a   Hedayati, Mohammad ^a   Merchant, Akil A ^a   Zhang, Yonggang ^a   Yu, Hsiang Hsuan M ^a   Kastan, Michael B ^b,c   Matsui, William ^a   DeWeese, Theodore L ^a,d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ataxia telangiectasia mutated; Ataxia telangiectasia mutated protein activation; Chloroquine; Hematopoietic progenitor cells; Low dose rate radiation

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; CHLOROQUINE; HEMATOPOIETIC PROGENITOR CELLS; LOW DOSE RATE; PROTEIN ACTIVATION;

BONE; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; FLOW CYTOMETRY; INTERNET PROTOCOLS; MAMMALS; PROTEINS; RADIATION PROTECTION;

RADIATION EFFECTS;

ATM PROTEIN; CD45 ANTIGEN; CHLOROQUINE; METHYLCELLULOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL ASSAY; CELL ISOLATION; CHIMERA; COLONY FORMING CELL; CONGENIC STRAIN; CONTROLLED STUDY; ENGRAFTMENT; FEMALE; FIBULA; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LETHAL DOSE; LOW ENERGY RADIATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; RADIATION PROTECTION; SURVIVAL RATE; TIBIA; VERTEBRA;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL CYCLE PROTEINS; CHLOROQUINE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; MALE; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; RADIATION CHIMERA; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; SURVIVAL RATE; TUMOR SUPPRESSOR PROTEINS;

EID: 84866742629     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.01.026     Document Type: Article

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