-
1
-
-
24144444669
-
Histopathology of pediatric nonalcoholic fatty liver disease
-
DOI 10.1002/hep.20842
-
J.B. Schwimmer, C. Behling, R. Newbury, R. Deutsch, C. Nievergelt, and N.J. Schork Histopathology of pediatric nonalcoholic fatty liver disease Hepatology 42 2005 641 649 (Pubitemid 41233657)
-
(2005)
Hepatology
, vol.42
, Issue.3
, pp. 641-649
-
-
Schwimmer, J.B.1
Behling, C.2
Newbury, R.3
Deutsch, R.4
Nievergelt, C.5
Schork, N.J.6
Lavine, J.E.7
-
2
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
DOI 10.1172/JCI29881
-
C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel Obesity induces a phenotypic switch in adipose tissue macrophage polarization J Clin Invest 117 2007 175 184 (Pubitemid 46048464)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
4
-
-
20444473800
-
Mechanisms of disease: Pathogenesis of nonalcoholic fatty liver disease
-
DOI 10.1038/ncpgasthep0084
-
A.J. Sanyal Mechanisms of disease: pathogenesis of nonalcoholic fatty liver disease Nat Clin Pract Gastroenterol Hepatol 2 2005 46 53 (Pubitemid 40812527)
-
(2005)
Nature Clinical Practice Gastroenterology and Hepatology
, vol.2
, Issue.1
, pp. 46-53
-
-
Sanyal, A.J.1
-
5
-
-
18244364864
-
NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
-
DOI 10.1053/jhep.2002.30692
-
S. Chitturi, S. Abeygunasekera, G.C. Farrell, J. Holmes-Walker, J.M. Hui, and C. Fung NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome Hepatology 35 2002 373 379 (Pubitemid 34106377)
-
(2002)
Hepatology
, vol.35
, Issue.2
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Farrell, G.C.3
Holmes-Walker, J.4
Hui, J.M.5
Fung, C.6
Karim, R.7
Lin, R.8
Samarasinghe, D.9
Liddle, C.10
Weltman, M.11
George, J.12
-
6
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
A.J. Sanyal, C. Campbell-Sargent, F. Mirshahi, W.B. Rizzo, M.J. Contos, and R.K. Sterling Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities Gastroenterology 120 2001 1183 1192 (Pubitemid 32246672)
-
(2001)
Gastroenterology
, vol.120
, Issue.5
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
Rizzo, W.B.4
Contos, M.J.5
Sterling, R.K.6
Luketic, V.A.7
Shiffman, M.L.8
Clore, J.N.9
-
7
-
-
65349162789
-
Adiponectin in health and disease: Evaluation of adiponectin-targeted drug development strategies
-
S. Shetty, C.M. Kusminski, and P.E. Scherer Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies Trends Pharmacol Sci 30 2009 234 239
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 234-239
-
-
Shetty, S.1
Kusminski, C.M.2
Scherer, P.E.3
-
8
-
-
33644794968
-
The association between plasma adiponectin and insulin sensitivity in humans depends on obesity
-
K. Kantartzis, A. Fritsche, O. Tschritter, C. Thamer, M. Haap, and S. Schafer The association between plasma adiponectin and insulin sensitivity in humans depends on obesity Obes Res 13 2005 1683 1691
-
(2005)
Obes Res
, vol.13
, pp. 1683-1691
-
-
Kantartzis, K.1
Fritsche, A.2
Tschritter, O.3
Thamer, C.4
Haap, M.5
Schafer, S.6
-
9
-
-
26244442273
-
The metabolism of isoforms of human adiponectin: Studies in human subjects and in experimental animals
-
DOI 10.1530/eje.1.01978
-
P.W. Peake, A.D. Kriketos, L.V. Campbell, Y. Shen, and J.A. Charlesworth The metabolism of isoforms of human adiponectin: studies in human subjects and in experimental animals Eur J Endocrinol 153 2005 409 417 (Pubitemid 41410498)
-
(2005)
European Journal of Endocrinology
, vol.153
, Issue.3
, pp. 409-417
-
-
Peake, P.W.1
Kriketos, A.D.2
Campbell, L.V.3
Shen, Y.4
Charlesworth, J.A.5
-
10
-
-
0037984387
-
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin: Implications for metabolic regulation and bioactivity
-
DOI 10.1074/jbc.M207198200
-
U.B. Pajvani, X. Du, T.P. Combs, A.H. Berg, M.W. Rajala, and T. Schulthess Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity J Biol Chem 278 2003 9073 9085 (Pubitemid 36800387)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 9073-9085
-
-
Pajvani, U.B.1
Du, X.2
Combs, T.P.3
Berg, A.H.4
Rajala, M.W.5
Schulthess, T.6
Engel, J.7
Brownlee, M.8
Scherer, P.E.9
-
11
-
-
34248197560
-
Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention
-
DOI 10.1128/MCB.00931-06
-
Z.V. Wang, T.D. Schraw, J.Y. Kim, T. Khan, M.W. Rajala, and A. Follenzi Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention Mol Cell Biol 27 2007 3716 3731 (Pubitemid 46726179)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.10
, pp. 3716-3731
-
-
Wang, Z.V.1
Schraw, T.D.2
Kim, J.-Y.3
Khan, T.4
Rajala, M.W.5
Follenzi, A.6
Scherer, P.E.7
-
12
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
DOI 10.1172/JCI200317797
-
A. Xu, Y. Wang, H. Keshaw, L.Y. Xu, K.S. Lam, and G.J. Cooper The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice J Clin Invest 112 2003 91 100 (Pubitemid 38056380)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.1
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.L.5
Cooper, G.J.S.6
-
13
-
-
79953723142
-
Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease
-
R. Dohil, S. Schmeltzer, B.L. Cabrera, T. Wang, J. Durelle, and K.B. Duke Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease Aliment Pharmacol Ther 33 2011 1036 1044
-
(2011)
Aliment Pharmacol Ther
, vol.33
, pp. 1036-1044
-
-
Dohil, R.1
Schmeltzer, S.2
Cabrera, B.L.3
Wang, T.4
Durelle, J.5
Duke, K.B.6
-
14
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
A.J. Sanyal, N. Chalasani, K.V. Kowdley, A. McCullough, A.M. Diehl, and N.M. Bass Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis N Engl J Med 362 2010 1675 1685
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
McCullough, A.4
Diehl, A.M.5
Bass, N.M.6
-
15
-
-
79955446251
-
Effect of vitamin e or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: The TONIC randomized controlled trial
-
J.E. Lavine, J.B. Schwimmer, M.L. Van Natta, J.P. Molleston, K.F. Murray, and P. Rosenthal Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial JAMA 305 2011 1659 1668
-
(2011)
JAMA
, vol.305
, pp. 1659-1668
-
-
Lavine, J.E.1
Schwimmer, J.B.2
Van Natta, M.L.3
Molleston, J.P.4
Murray, K.F.5
Rosenthal, P.6
-
16
-
-
0019940282
-
Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis
-
W.A. Gahl, N. Bashan, F. Tietze, I. Bernardini, and J.D. Schulman Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis Science 217 1982 1263 1265 (Pubitemid 12028677)
-
(1982)
Science
, vol.217
, Issue.4566
, pp. 1263-1265
-
-
Gahl, W.A.1
Bashan, N.2
-
17
-
-
41049099937
-
Antioxidant effect of cysteamine in brain cortex of young rats
-
DOI 10.1007/s11064-007-9486-7
-
A. Kessler, M. Biasibetti, D.A. da Silva Melo, M. Wajner, C.S. Dutra-Filho, and A.T. de Souza Wyse Antioxidant effect of cysteamine in brain cortex of young rats Neurochem Res 33 2008 737 744 (Pubitemid 351423138)
-
(2008)
Neurochemical Research
, vol.33
, Issue.5
, pp. 737-744
-
-
Kessler, A.1
Biasibetti, M.2
Da Silva Melo, D.A.3
Wajner, M.4
Dutra-Filho, C.S.5
De Souza Wyse, A.T.6
Wannmacher, C.M.D.7
-
18
-
-
72049095333
-
Twice-daily cysteamine bitartrate therapy for children with cystinosis
-
e1-3
-
R. Dohil, M. Fidler, J.A. Gangoiti, F. Kaskel, J.A. Schneider, and B.A. Barshop Twice-daily cysteamine bitartrate therapy for children with cystinosis J Pediatr 156 2010 71 75 e1-3
-
(2010)
J Pediatr
, vol.156
, pp. 71-75
-
-
Dohil, R.1
Fidler, M.2
Gangoiti, J.A.3
Kaskel, F.4
Schneider, J.A.5
Barshop, B.A.6
-
19
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
20
-
-
74949095908
-
Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects
-
Y. Kamada, T. Nakamura, T. Funahashi, M. Ryo, H. Nishizawa, and Y. Okauchi Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects J Clin Gastroenterol 43 2009 995 1000
-
(2009)
J Clin Gastroenterol
, vol.43
, pp. 995-1000
-
-
Kamada, Y.1
Nakamura, T.2
Funahashi, T.3
Ryo, M.4
Nishizawa, H.5
Okauchi, Y.6
-
21
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
DOI 10.1038/nm788
-
T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, and S. Uchida Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase Nat Med 8 2002 1288 1295 (Pubitemid 35373562)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
22
-
-
67649598622
-
Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization
-
J. Fukushima, Y. Kamada, H. Matsumoto, Y. Yoshida, H. Ezaki, and T. Takemura Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization Hepatol Res 39 2009 724 738
-
(2009)
Hepatol Res
, vol.39
, pp. 724-738
-
-
Fukushima, J.1
Kamada, Y.2
Matsumoto, H.3
Yoshida, Y.4
Ezaki, H.5
Takemura, T.6
-
23
-
-
0347379841
-
Role of Disulfide Bonds in Acrp30/Adiponectin Structure and Signaling Specificity: Different oligomers activate different signal transduction pathways
-
DOI 10.1074/jbc.M309469200
-
T.S. Tsao, E. Tomas, H.E. Murrey, C. Hug, D.H. Lee, and N.B. Ruderman Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways J Biol Chem 278 2003 50810 50817 (Pubitemid 37548930)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 50810-50817
-
-
Tsao, T.-S.1
Tomas, E.2
Murrey, H.E.3
Hug, C.4
Lee, D.H.5
Ruderman, N.B.6
Heuser, J.E.7
Lodish, H.F.8
-
24
-
-
77957312329
-
From antibodies to adiponectin: Role of ERp44 in sizing and timing protein secretion
-
M. Cortini, and R. Sitia From antibodies to adiponectin: role of ERp44 in sizing and timing protein secretion Diabetes Obes Metab 12 Suppl 2 2010 39 47
-
(2010)
Diabetes Obes Metab
, vol.12
, Issue.SUPPL. 2
, pp. 39-47
-
-
Cortini, M.1
Sitia, R.2
-
25
-
-
48449107159
-
Thiol chemistry and specificity in redox signaling
-
C.C. Winterbourn, and M.B. Hampton Thiol chemistry and specificity in redox signaling Free Radic Biol Med 45 2008 549 561
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 549-561
-
-
Winterbourn, C.C.1
Hampton, M.B.2
-
26
-
-
53749089841
-
A novel approach to enhancing cellular glutathione levels
-
P. Maher, J. Lewerenz, C. Lozano, and J.L. Torres A novel approach to enhancing cellular glutathione levels J Neurochem 107 2008 690 700
-
(2008)
J Neurochem
, vol.107
, pp. 690-700
-
-
Maher, P.1
Lewerenz, J.2
Lozano, C.3
Torres, J.L.4
-
27
-
-
14644415488
-
Mechanism for the inhibition of transglutaminase 2 by cystamine
-
DOI 10.1016/j.bcp.2004.12.011
-
T.M. Jeitner, E.J. Delikatny, J. Ahlqvist, H. Capper, and A.J. Cooper Mechanism for the inhibition of transglutaminase 2 by cystamine Biochem Pharmacol 69 2005 961 970 (Pubitemid 40312713)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.6
, pp. 961-970
-
-
Jeitner, T.M.1
Delikatny, E.J.2
Ahlqvist, J.3
Capper, H.4
Cooper, A.J.L.5
-
28
-
-
0030900790
-
A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-κB
-
A. Mirza, S.L. Liu, E. Frizell, J. Zhu, S. Maddukuri, and J. Martinez A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-κB Am J Physiol 272 1997 G281 G288
-
(1997)
Am J Physiol
, vol.272
-
-
Mirza, A.1
Liu, S.L.2
Frizell, E.3
Zhu, J.4
Maddukuri, S.5
Martinez, J.6
-
29
-
-
34347338702
-
Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-Lα
-
DOI 10.1128/MCB.02279-06
-
L. Qiang, H. Wang, and S.R. Farmer Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha Mol Cell Biol 27 2007 4698 4707 (Pubitemid 47016124)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.13
, pp. 4698-4707
-
-
Qiang, L.1
Wang, H.2
Farmer, S.R.3
-
30
-
-
79956214173
-
Role of redox environment on the oligomerization of higher molecular weight adiponectin
-
D.B. Briggs, R.M. Giron, P.R. Malinowski, M. Nunez, and T.S. Tsao Role of redox environment on the oligomerization of higher molecular weight adiponectin BMC Biochem 12 2011 24 35
-
(2011)
BMC Biochem
, vol.12
, pp. 24-35
-
-
Briggs, D.B.1
Giron, R.M.2
Malinowski, P.R.3
Nunez, M.4
Tsao, T.S.5
-
31
-
-
33744931367
-
Understanding intestinal cysteamine bitartrate absorption
-
DOI 10.1016/j.jpeds.2006.01.050, PII S0022347606000977
-
R. Dohil, M. Fidler, B.A. Barshop, J. Gangoiti, R. Deutsch, and M. Martin Understanding intestinal cysteamine bitartrate absorption J Pediatr 148 2006 764 769 (Pubitemid 43849821)
-
(2006)
Journal of Pediatrics
, vol.148
, Issue.6
, pp. 764-769
-
-
Dohil, R.1
Fidler, M.2
Barshop, B.A.3
Gangoiti, J.4
Deutsch, R.5
Martin, M.6
Schneider, J.A.7
|