메뉴 건너뛰기




Volumn 35, Issue 5, 2012, Pages 504-509

Prostate cancer, androgen deprivation therapy, obesity, the metabolic syndrome, type 2 diabetes, and cardiovascular disease: A review

Author keywords

androgen deprivation therapy; cardiovascular disease; metabolic syndrome; prostate cancer; type 2 diabetes

Indexed keywords

ACETYLSALICYLIC ACID; ANDROSTANOLONE; ANTIANDROGEN; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; BICALUTAMIDE; FLUTAMIDE; GONADORELIN AGONIST; GONADORELIN DERIVATIVE; GOSERELIN; INSULIN SENSITIZING AGENT; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

EID: 84866734902     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e318201a406     Document Type: Review
Times cited : (63)

References (71)
  • 1
    • 84872220328 scopus 로고    scopus 로고
    • CancerStats Key Facts on Prostate Cancer. Cancer Research UK last accessed 09/06/2010
    • CancerStats Key Facts on Prostate Cancer. Cancer Research UK.http://info.cancerreseachuk.org/cancerstats/types/prostate/?a=5441 (last accessed 09/06/2010).
  • 4
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome-A new worldwide definition
    • Alberti KG, Zimmet P, Shaw J. The metabolic syndrome-A new worldwide definition. Lancet. 2005;366:1059-1062.
    • (2005) Lancet. , vol.366 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 6
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 7
    • 0036636871 scopus 로고    scopus 로고
    • Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941
    • Huggins C, Hodges CV. Studies on prostatic cancer: I. the effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941. J Urol. 2002;168:9-12.
    • (2002) J Urol , vol.168 , pp. 9-12
    • Huggins, C.1    Hodges, C.V.2
  • 8
    • 0014088849 scopus 로고
    • Treatment and survival of patients with cancer of the prostate
    • The Veterans Administration Co-operative Urological Research Group
    • The Veterans Administration Co-operative Urological Research Group. Treatment and survival of patients with cancer of the prostate. Surg Gynecol Obstet. 1967;124:1011-1017.
    • (1967) Surg Gynecol Obstet. , vol.124 , pp. 1011-1017
  • 9
    • 67149130467 scopus 로고    scopus 로고
    • Androgen deprivation in prostate cancer-step by step
    • Albertsen P. Androgen deprivation in prostate cancer-step by step. N Engl J Med. 2009;360:2572-2574.
    • (2009) N Engl J Med. , vol.360 , pp. 2572-2574
    • Albertsen, P.1
  • 10
    • 0021072579 scopus 로고
    • New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens
    • Labrie F, Dupont A, Belanger A, et al. New approach in the treatment of prostate cancer: complete instead of partial withdrawal of androgens. Prostate. 1983;4:579-594.
    • (1983) Prostate. , vol.4 , pp. 579-594
    • Labrie, F.1    Dupont, A.2    Belanger, A.3
  • 11
    • 0024324367 scopus 로고
    • A controlled trial of leuprolide with and without flumatide in prostatic carcinoma
    • Erratum N Eng J Med 19893211420
    • Crawford ED, Eisenberger MA, McLeod DG et al. A controlled trial of leuprolide with and without flumatide in prostatic carcinoma. N Eng J Med. 1989;321:419-424. [Erratum N Eng J Med. 1989;321:1420].
    • (1989) N Eng J Med. , vol.321 , pp. 419-424
    • Crawford, E.D.1    Eisenberger, M.A.2    McLeod, D.G.3
  • 12
    • 0035424063 scopus 로고    scopus 로고
    • Phase 111 radiation therapy group (RTOG) trial 86-10 of androgen deprivation therapy adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate
    • Pilepich MV, Winter K, John MJ, et al. Phase 111 radiation therapy group (RTOG) trial 86-10 of androgen deprivation therapy adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate. Int J Radiat Oncol Biol Phys. 2001;50:1243-1252.
    • (2001) Int J Radiat Oncol Biol Phys. , vol.50 , pp. 1243-1252
    • Pilepich, M.V.1    Winter, K.2    John, M.J.3
  • 13
    • 37249033596 scopus 로고    scopus 로고
    • Concomitant and adjuvant androgen deprivation (ADT) with external beam irradiation (RT) for locally advanced prostate cancer: 6 months versus 3 years AADT-Results of the randomised EORTC phase III trial 22961
    • Bolla M, van Tienhoven G, de Reijke TM, et al EORTC Radiation Oncology and Genito-Urinary Tract Cancer Groups. Concomitant and adjuvant androgen deprivation (ADT) with external beam irradiation (RT) for locally advanced prostate cancer: 6 months versus 3 years AADT-Results of the randomised EORTC phase III trial 22961. J Clin Oncol. 2007;25:5014.
    • (2007) J Clin Oncol. , vol.25 , pp. 5014
    • Bolla, M.1    Van Tienhoven, G.2    De Reijke, T.M.3
  • 14
    • 34248339065 scopus 로고    scopus 로고
    • Short-vs long-term androgen suppression plus external beam radiation therapy and survival in men of advanced age with node-negative high-risk adenocarcinoma of the prostate
    • D'Amico AV, Denham JW, Bolla M, et al. Short-vs long-term androgen suppression plus external beam radiation therapy and survival in men of advanced age with node-negative high-risk adenocarcinoma of the prostate. Cancer. 2007;109:2004-2010.
    • (2007) Cancer. , vol.109 , pp. 2004-2010
    • D'Amico, A.V.1    Denham, J.W.2    Bolla, M.3
  • 15
    • 0042140586 scopus 로고    scopus 로고
    • Is bicalutamide equivalent to goserelin for prostate volume reduction before radiation therapy? A prospective, observational study
    • Henderson A, Langley SE, Laing RW. Is bicalutamide equivalent to goserelin for prostate volume reduction before radiation therapy? A prospective, observational study. Clin Oncol (R Coll Radiol). 2003;15:318-321.
    • (2003) Clin Oncol (R Coll Radiol). , vol.15 , pp. 318-321
    • Henderson, A.1    Langley, S.E.2    Laing, R.W.3
  • 16
    • 33746394264 scopus 로고    scopus 로고
    • Interstitial low dose rate brachytherapy for prostate cancer-A focus on intermediate-and high-risk disease
    • Khaksar SJ, Langley SE, Lovell D, et al. Interstitial low dose rate brachytherapy for prostate cancer-a focus on intermediate-and high-risk disease. Clin Oncol (R Coll Radiol). 2006;18: 513-518.
    • (2006) Clin Oncol (R Coll Radiol) , vol.18 , pp. 513-518
    • Khaksar, S.J.1    Langley, S.E.2    Lovell, D.3
  • 17
    • 0031051097 scopus 로고    scopus 로고
    • Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy: Report of Radiation Therapy Oncology Group Protocol 85-31
    • Pilepich MV, Caplan R, Byhardt RW, et al. Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy: report of Radiation Therapy Oncology Group Protocol 85-31. J Clin Oncol. 1997;15:1013-1021.
    • (1997) J Clin Oncol. , vol.15 , pp. 1013-1021
    • Pilepich, M.V.1    Caplan, R.2    Byhardt, R.W.3
  • 18
    • 65549123613 scopus 로고    scopus 로고
    • Impact of the duration of adjuvant hormonal therapy in patients with locally advanced prostate cancer treated with radiotherapy: A secondary analysis of RTOG 85-31
    • Souhami L, Bae K, Pilepich M, et al. Impact of the duration of adjuvant hormonal therapy in patients with locally advanced prostate cancer treated with radiotherapy: a secondary analysis of RTOG 85-31. J Clin Oncol. 2009;27:2137-2143.
    • (2009) J Clin Oncol. , vol.27 , pp. 2137-2143
    • Souhami, L.1    Bae, K.2    Pilepich, M.3
  • 19
    • 0025050724 scopus 로고
    • Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity
    • Zumoff B, Strain GW, Miller LK, et al. Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. J Clin Endocrinol Metab. 1990;71:929-931.
    • (1990) J Clin Endocrinol Metab. , vol.71 , pp. 929-931
    • Zumoff, B.1    Strain, G.W.2    Miller, L.K.3
  • 20
    • 24144493455 scopus 로고    scopus 로고
    • Androgens, insulin resistance and vascular disease in men
    • Kapoor D, Malkin CJ, Channer KS, et al. Androgens, insulin resistance and vascular disease in men. Clin Endocrinol (Oxford). 2005;63:239-250.
    • (2005) Clin Endocrinol (Oxford). , vol.63 , pp. 239-250
    • Kapoor, D.1    Malkin, C.J.2    Channer, K.S.3
  • 21
    • 0033304558 scopus 로고    scopus 로고
    • Leptin and androgens in male obesity: Evidence for leptin contribution to reduced androgen levels
    • Isidori AM, Caprio M, Strollo F, et al. Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels. J Clin Endocrinol Metab. 1999;84:3673-3680.
    • (1999) J Clin Endocrinol Metab. , vol.84 , pp. 3673-3680
    • Isidori, A.M.1    Caprio, M.2    Strollo, F.3
  • 22
    • 2342644814 scopus 로고    scopus 로고
    • Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men
    • Laaksonen DE, Niskanen L, Punnonen K, et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care. 2004;27: 1036-1041.
    • (2004) Diabetes Care. , vol.27 , pp. 1036-1041
    • Laaksonen, D.E.1    Niskanen, L.2    Punnonen, K.3
  • 23
    • 0026547429 scopus 로고
    • Interrelation between plasma testosterone and plasma insulin in healthy adult men: The Telecom Study
    • Simon D, Preziosi P, Barrett-Connor E, et al. Interrelation between plasma testosterone and plasma insulin in healthy adult men: the Telecom Study. Diabetologia. 1992;35:173-177.
    • (1992) Diabetologia. , vol.35 , pp. 173-177
    • Simon, D.1    Preziosi, P.2    Barrett-Connor, E.3
  • 24
    • 0027225982 scopus 로고
    • Sex hormones and hemostatic risk factors for coronary heart disease in men with hypertension
    • Phillips GB, Jing TY, Resnik LM, et al. Sex hormones and hemostatic risk factors for coronary heart disease in men with hypertension. J Hypertension. 1993;11:699-702.
    • (1993) J Hypertension. , vol.11 , pp. 699-702
    • Phillips, G.B.1    Jing, T.Y.2    Resnik, L.M.3
  • 25
    • 0034106347 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: Prospective results from the Massachusetts male aging study
    • Stellato RK, Feldman HA, Hamdy O, et al. Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study. Diabetes Care. 2000;23:490-494.
    • (2000) Diabetes Care. , vol.23 , pp. 490-494
    • Stellato, R.K.1    Feldman, H.A.2    Hamdy, O.3
  • 26
    • 0036357643 scopus 로고    scopus 로고
    • Endogenous sex hormones and the development of type 2 diabetes in older men and women: The Rancho Bernardo study
    • Oh JY, Barrett-Connor E, Wedick NM, et al. Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study. Diabetes Care. 2002;25: 55-60.
    • (2002) Diabetes Care. , vol.25 , pp. 55-60
    • Oh, J.Y.1    Barrett-Connor, E.2    Wedick, N.M.3
  • 27
    • 8744228132 scopus 로고    scopus 로고
    • Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes
    • Dhindsa S, Prabhakar S, Sethi M, et al. Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes. J Clin Endocrinol Metab. 2004;89:5462-5468.
    • (2004) J Clin Endocrinol Metab. , vol.89 , pp. 5462-5468
    • Dhindsa, S.1    Prabhakar, S.2    Sethi, M.3
  • 28
    • 0034703229 scopus 로고    scopus 로고
    • Role of brain insulin receptor in control of body weight and reproduction
    • Bruning JC, Gautam D, Burks DJ, et al. Role of brain insulin receptor in control of body weight and reproduction. Science. 2000;289:2122-2125.
    • (2000) Science. , vol.289 , pp. 2122-2125
    • Bruning, J.C.1    Gautam, D.2    Burks, D.J.3
  • 29
    • 18844362098 scopus 로고    scopus 로고
    • Increasing insulin resistance is associated with decrease in Leydig cell testosterone secretion in men
    • Pitteloud N, Hardin M, Dwyer AA, et al. Increasing insulin resistance is associated with decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005;90:2636-2641.
    • (2005) J Clin Endocrinol Metab. , vol.90 , pp. 2636-2641
    • Pitteloud, N.1    Hardin, M.2    Dwyer, A.A.3
  • 30
    • 0026621219 scopus 로고
    • The effects of testosterone on insulin sensitivity in male rats
    • Holmang A, Bjorntorp P. The effects of testosterone on insulin sensitivity in male rats. Acta Physiol Scand. 1992;146:505-510.
    • (1992) Acta Physiol Scand. , vol.146 , pp. 505-510
    • Holmang, A.1    Bjorntorp, P.2
  • 31
    • 0035654282 scopus 로고    scopus 로고
    • Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: A 3-month randomized placebo-controlled trial
    • Simon D, Charles MA, Lahlou N, et al. Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: a 3-month randomized placebo-controlled trial. Diabetes Care. 2001;24:2149-2151.
    • (2001) Diabetes Care. , vol.24 , pp. 2149-2151
    • Simon, D.1    Charles, M.A.2    Lahlou, N.3
  • 32
    • 0026929033 scopus 로고
    • Androgen treatment of middle-aged, obese men: Effects on metabolism, muscle and adipose tissues
    • Marin P, Krotkiewski M, Bjorntorp P. Androgen treatment of middle-aged, obese men: effects on metabolism, muscle and adipose tissues. European Journal of Medicine. 1992;1:329-336.
    • (1992) European Journal of Medicine. , vol.1 , pp. 329-336
    • Marin, P.1    Krotkiewski, M.2    Bjorntorp, P.3
  • 33
    • 3242667701 scopus 로고    scopus 로고
    • The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men
    • Malkin CJ, Pugh PJ, Jones RD, et al. The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab. 2004;89: 3313-3318.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3313-3318
    • Malkin, C.J.1    Pugh, P.J.2    Jones, R.D.3
  • 34
    • 33745684473 scopus 로고    scopus 로고
    • Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogo-nadal men with type 2 diabetes
    • Kapoor D, Goodwin E, Channer KS, et al. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogo-nadal men with type 2 diabetes. J Clinical Endocrinol. 2006;154: 899-906.
    • (2006) J Clinical Endocrinol , vol.154 , pp. 899-906
    • Kapoor, D.1    Goodwin, E.2    Channer, K.S.3
  • 35
    • 0038823605 scopus 로고    scopus 로고
    • Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency
    • Boyanov MA, Boneva Z, Christov VG. Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency. Aging Male. 2003;6:1-7.
    • (2003) Aging Male , vol.6 , pp. 1-7
    • Boyanov, M.A.1    Boneva, Z.2    Christov, V.G.3
  • 36
    • 2342523374 scopus 로고    scopus 로고
    • Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control
    • Corrales JJ, Burgo RM, Garca-Berrocal B, et al. Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control. Metabolism. 2004;53:666-672.
    • (2004) Metabolism. , vol.53 , pp. 666-672
    • Corrales, J.J.1    Burgo, R.M.2    Garca-Berrocal, B.3
  • 37
    • 34547660521 scopus 로고    scopus 로고
    • Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men
    • Basu R, Dalla Man C, Campioni M, et al. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care. 2007;30: 1972-1978.
    • (2007) Diabetes Care , vol.30 , pp. 1972-1978
    • Basu, R.1    Dalla Man, C.2    Campioni, M.3
  • 38
    • 60349088152 scopus 로고    scopus 로고
    • Healthier lifestyle predicts higher circulating testosterone in older men
    • Yeap BB, Almeida OP, Hyde Z, et al. Healthier lifestyle predicts higher circulating testosterone in older men. Clin Endocrinol. 2009:70;455-463.
    • (2009) Clin Endocrinol , vol.70 , pp. 455-463
    • Yeap, B.B.1    Almeida, O.P.2    Hyde, Z.3
  • 39
    • 33749539357 scopus 로고    scopus 로고
    • The rising prevalence of androgen deprivation among older American men since the advent of prostate-specific antigen testing: A population-based cohort study
    • Barry MJ, Delorenzo MA, Walker-Corkery ES, et al. The rising prevalence of androgen deprivation among older American men since the advent of prostate-specific antigen testing: a population-based cohort study. BJU Int. 2006;98:973-978.
    • (2006) BJU Int. , vol.98 , pp. 973-978
    • Barry, M.J.1    Delorenzo, M.A.2    Walker-Corkery, E.S.3
  • 40
    • 0036062598 scopus 로고    scopus 로고
    • Long-term effects of androgen deprivation therapy in prostate cancer patients
    • Basaria S, Lieb J, Tang AM, et al. Long-term effects of androgen deprivation therapy in prostate cancer patients. Clin Endocrinol (Oxford). 2002;56:779-786.
    • (2002) Clin Endocrinol (Oxford). , vol.56 , pp. 779-786
    • Basaria, S.1    Lieb, J.2    Tang, A.M.3
  • 41
    • 0042130570 scopus 로고    scopus 로고
    • Changes in body composition during combined androgen blockade for prostate cancer
    • Smith MR. Changes in body composition during combined androgen blockade for prostate cancer. Clin Prostate Cancer. 2003;2:18-21.
    • (2003) Clin Prostate Cancer. , vol.2 , pp. 18-21
    • Smith, M.R.1
  • 42
    • 33646029746 scopus 로고    scopus 로고
    • Insulin sensitivity during combined androgen blockade for prostate cancer
    • Smith MR, Lee H, Nathan DM. Insulin sensitivity during combined androgen blockade for prostate cancer. J Clin Endocrinol Metab. 2006;91:1305-1308.
    • (2006) J Clin Endocrinol Metab. , vol.91 , pp. 1305-1308
    • Smith, M.R.1    Lee, H.2    Nathan, D.M.3
  • 43
    • 0034847215 scopus 로고    scopus 로고
    • The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer
    • Smith JC, Bennett S, Evans LM, et al. The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab. 2001;86:4261-4267.
    • (2001) J Clin Endocrinol Metab. , vol.86 , pp. 4261-4267
    • Smith, J.C.1    Bennett, S.2    Evans, L.M.3
  • 44
    • 0037326906 scopus 로고    scopus 로고
    • Testosterone suppression in men with prostate cancer leads to an increase in arterial stiffness and hyperinsulinaemia
    • Dockery F, Bulpitt CJ, Agarwal S, et al. Testosterone suppression in men with prostate cancer leads to an increase in arterial stiffness and hyperinsulinaemia. Clin Sci (London). 2003;104:195-201.
    • (2003) Clin Sci (London). , vol.104 , pp. 195-201
    • Dockery, F.1    Bulpitt, C.J.2    Agarwal, S.3
  • 45
    • 33748474608 scopus 로고    scopus 로고
    • Metabolic syndrome in men with prostate cancer undergoing long-term Androgen-deprivation therapy
    • Braga-Basaria M, Dobs AS, Muller DC, et al. Metabolic syndrome in men with prostate cancer undergoing long-term Androgen-deprivation therapy. J Clin Oncol. 2006;24:3979-3983.
    • (2006) J Clin Oncol. , vol.24 , pp. 3979-3983
    • Braga-Basaria, M.1    Dobs, A.S.2    Muller, D.C.3
  • 46
    • 33749058933 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer
    • Keating NL, O'Malley AJ, Smith MR. Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol. 2006;24:4448-4456.
    • (2006) J Clin Oncol. , vol.24 , pp. 4448-4456
    • Keating, N.L.1    O'Malley, A.J.2    Smith, M.R.3
  • 47
    • 37349025015 scopus 로고    scopus 로고
    • Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer
    • Lage MJ, Barber BL, Markus RA. Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer. Urology. 2007;70:1104-1108.
    • (2007) Urology. , vol.70 , pp. 1104-1108
    • Lage, M.J.1    Barber, B.L.2    Markus, R.A.3
  • 48
    • 35148842094 scopus 로고    scopus 로고
    • Risk of new-onset diabetes mellitus and worsening glycaemic variables for established diabetes in men undergoing androgen-deprivation therapy for prostate cancer
    • Derweesh IH, Diblasio CJ, Kincade MC, et al. Risk of new-onset diabetes mellitus and worsening glycaemic variables for established diabetes in men undergoing androgen-deprivation therapy for prostate cancer. BJU Int. 2007;100:1060-1065.
    • (2007) BJU Int. , vol.100 , pp. 1060-1065
    • Derweesh, I.H.1    Diblasio, C.J.2    Kincade, M.C.3
  • 49
    • 33644857333 scopus 로고    scopus 로고
    • Bicalutamide 150mg plus standard versus standard care alone for early prostate cancer
    • 446
    • Mcleod DG, Iversen P, See WA, et al, Casodex early prostate cancer trialists' group. Bicalutamide 150mg plus standard versus standard care alone for early prostate cancer. BJU Int. 2006;97: 247-225, 446.
    • (2006) BJU Int. , vol.97 , pp. 247-225
    • McLeod, D.G.1    Iversen, P.2    See, W.A.3
  • 50
    • 35548937873 scopus 로고    scopus 로고
    • Androgen deprivation therapy for localized prostate cancer and the risk of cardiovascular mortality
    • Tasi HK, D'Amico AV, Sadetsky N, et al. Androgen deprivation therapy for localized prostate cancer and the risk of cardiovascular mortality. J Natl Cancer Inst. 2007;99:1516-1524.
    • (2007) J Natl Cancer Inst. , vol.99 , pp. 1516-1524
    • Tasi, H.K.1    D'Amico, A.V.2    Sadetsky, N.3
  • 51
    • 34648828214 scopus 로고    scopus 로고
    • Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer
    • Saigal CS, Gore JL, Krupski TL, et al. Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer. Cancer. 2007;110:1493-1500.
    • (2007) Cancer. , vol.110 , pp. 1493-1500
    • Saigal, C.S.1    Gore, J.L.2    Krupski, T.L.3
  • 52
    • 34347271955 scopus 로고    scopus 로고
    • Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions
    • D'Amico AV, Denham JW, Crook J, et al. Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions. J Clin Oncol. 2007;25: 2420-2425.
    • (2007) J Clin Oncol , vol.25 , pp. 2420-2425
    • D'Amico, A.V.1    Denham, J.W.2    Crook, J.3
  • 53
    • 16344378660 scopus 로고    scopus 로고
    • Impact of short course hormonal therapy on overall and cancer specific survival after permanent prostate brachytherapy
    • Beyer DC, McKeough T, Thomas T. Impact of short course hormonal therapy on overall and cancer specific survival after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2005;61:1299-1305.
    • (2005) Int J Radiat Oncol Biol Phys. , vol.61 , pp. 1299-1305
    • Beyer, D.C.1    McKeough, T.2    Thomas, T.3
  • 54
    • 2942520997 scopus 로고    scopus 로고
    • Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
    • Coughlin SS, Calle EE, Teras LR, et al. Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol. 2004;159:1160-1167.
    • (2004) Am J Epidemiol. , vol.159 , pp. 1160-1167
    • Coughlin, S.S.1    Calle, E.E.2    Teras, L.R.3
  • 55
    • 33645963173 scopus 로고    scopus 로고
    • Mortality in people with type 2 diabetes in the UK
    • Mulnier HE, Seaman HE, Raleigh VS, et al. Mortality in people with type 2 diabetes in the UK. Diabet Med. 2006;23:516-521.
    • (2006) Diabet Med. , vol.23 , pp. 516-521
    • Mulnier, H.E.1    Seaman, H.E.2    Raleigh, V.S.3
  • 56
    • 68449088664 scopus 로고    scopus 로고
    • Does diabetes therapy influence the risk of cancer?
    • Smith U, Gale EA. Does diabetes therapy influence the risk of cancer? Diabetologia. 2009;52:1699-1708.
    • (2009) Diabetologia. , vol.52 , pp. 1699-1708
    • Smith, U.1    Gale, E.A.2
  • 57
    • 34247869042 scopus 로고    scopus 로고
    • The role of obesity and related metabolic disturbances in cancers of the colon, prostate and pancreas
    • Giovannucci E, Michaud D. The role of obesity and related metabolic disturbances in cancers of the colon, prostate and pancreas. Gastroenterology. 2007;132:2208-2225.
    • (2007) Gastroenterology. , vol.132 , pp. 2208-2225
    • Giovannucci, E.1    Michaud, D.2
  • 58
    • 40349112853 scopus 로고    scopus 로고
    • Metabolic syndrome, hyperinsulinaemia, and cancer
    • Hsu IR, Kim SP, Kabir M, et al. Metabolic syndrome, hyperinsulinaemia, and cancer. Am J Clin Nutr. 2007;86: 867S-771S.
    • (2007) Am J Clin Nutr. , vol.86
    • Hsu, I.R.1    Kim, S.P.2    Kabir, M.3
  • 59
    • 0036550234 scopus 로고    scopus 로고
    • Signaling through IGF-1 and insulin receptors: Where is the specificity?
    • Kim JJ, Accili D. Signaling through IGF-1 and insulin receptors: where is the specificity? Growth Horm IGF Res. 2002;12: 84-90.
    • (2002) Growth Horm IGF Res , vol.12 , pp. 84-90
    • Kim, J.J.1    Accili, D.2
  • 60
    • 0032932822 scopus 로고    scopus 로고
    • Insulin receptor isoform A, a newly recognised, high affinity insulin-like growth factor II receptor in fetal and cancer cells
    • Frasca F, Pandini G, Scalia P et al. Insulin receptor isoform A, a newly recognised, high affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol. 1999;19: 3278-3288.
    • (1999) Mol Cell Biol. , vol.19 , pp. 3278-3288
    • Frasca, F.1    Pandini, G.2    Scalia, P.3
  • 61
    • 38449105596 scopus 로고    scopus 로고
    • Association of diet-induced hyperinsulinemia with accelerated growth of prostate cancer (LNCaP) xenografts
    • Venkateswaran V, Haddad AQ, Fleshner NE et al. Association of diet-induced hyperinsulinemia with accelerated growth of prostate cancer (LNCaP) xenografts. J Natl Cancer Inst. 2007;99: 1793-1800.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1793-1800
    • Venkateswaran, V.1    Haddad, A.Q.2    Fleshner, N.E.3
  • 62
    • 33845227353 scopus 로고    scopus 로고
    • The metabolic syndrome is associated with reduced risk of prostate cancer
    • Tande AJ, Platz EA, Folsom AR. The metabolic syndrome is associated with reduced risk of prostate cancer. Am J Epidemiol. 2006;164:1094-1102.
    • (2006) Am J Epidemiol. , vol.164 , pp. 1094-1102
    • Tande, A.J.1    Platz, E.A.2    Folsom, A.R.3
  • 63
    • 4944223630 scopus 로고    scopus 로고
    • Metabolic syndrome and the risk of prostate cancer in Finnish men: A population-based study
    • Laukkanen JA, Laaksonen DE, Niskanen L, et al. Metabolic syndrome and the risk of prostate cancer in Finnish men: a population-based study. Cancer Epidemiol Biomarkers Prev. 2004;13:1646-1650.
    • (2004) Cancer Epidemiol Biomarkers Prev. , vol.13 , pp. 1646-1650
    • Laukkanen, J.A.1    Laaksonen, D.E.2    Niskanen, L.3
  • 64
    • 0027441048 scopus 로고
    • Insulin resistance in insulin-dependent diabetic patients with microalbuminuria
    • Yip J, Mattock MB, Morocutti A, et al. Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Lancet. 1993;342:883-887.
    • (1993) Lancet. , vol.342 , pp. 883-887
    • Yip, J.1    Mattock, M.B.2    Morocutti, A.3
  • 65
    • 0024410794 scopus 로고
    • Albumi-nuria reflects widespread vascular damage: The Steno hypothesis
    • Deckert T, Feldt-rasmussen B, Borch-Johnsen K, et al. Albumi-nuria reflects widespread vascular damage: the Steno hypothesis. Diabetologia. 1989;32:219-226.
    • (1989) Diabetologia. , vol.32 , pp. 219-226
    • Deckert, T.1    Feldt-Rasmussen, B.2    Borch-Johnsen, K.3
  • 66
    • 1542432170 scopus 로고    scopus 로고
    • Guidelines for the management of hypertension: Report of the fourth working party of the British Hypertension Society, 2004-BHS IV
    • Williams B, Poulter NR, Brown MJ, et al. Guidelines for the management of hypertension: report of the fourth working party of the British Hypertension Society, 2004-BHS IV. J Human Hypertension. 2004;18:139-185.
    • (2004) J Human Hypertension. , vol.18 , pp. 139-185
    • Williams, B.1    Poulter, N.R.2    Brown, M.J.3
  • 67
    • 34548420712 scopus 로고    scopus 로고
    • Effects of a fixed combination of Perindopril and Indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
    • Patel A. Effects of a fixed combination of Perindopril and Indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet. 2007;370:829-840.
    • (2007) Lancet. , vol.370 , pp. 829-840
    • Patel, A.1
  • 68
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an Angiotensin-Converting-Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients
    • The Heart Outcomes Prevention Evaluation Study Investigators
    • The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an Angiotensin-Converting-Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients. N Engl J Med. 2000;342:145-153.
    • (2000) N Engl J Med. , vol.342 , pp. 145-153
  • 69
    • 38349006055 scopus 로고    scopus 로고
    • Management of hypertension in adults in primary care
    • Hypertension June National institute for Health and Clinical Excellence Accessed: Jan 2010
    • Hypertension. Management of hypertension in adults in primary care. NICE clinical guideline 34. June 2006. National institute for Health and Clinical Excellence. Available from http://www. nice.org.uk (Accessed: Jan 2010).
    • (2006) NICE Clinical Guideline , vol.34
  • 70
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study Group.
    • UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837-853.
    • (1998) Lancet. , vol.352 , pp. 837-853
  • 71
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group.
    • Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977-986.
    • (1993) N Engl J Med. , vol.329 , pp. 977-986


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.