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Volumn 138, Issue 9, 2012, Pages 1607-1612

Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors

Author keywords

Cyclin D1; Leptin; MMTV Wnt 1 tumor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLIN D1; CYTOKERATIN 8; FORMALDEHYDE; LEPTIN; PROTEIN KINASE B; WNT1 PROTEIN;

EID: 84866734141     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1252-9     Document Type: Article
Times cited : (17)

References (29)
  • 1
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • Alt JR, Cleveland JL, Hannink M, Diehl JA (2000) Phosphorylation- dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 14(24):3102-3114
    • (2000) Genes Dev , vol.14 , Issue.24 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 2
    • 34547819751 scopus 로고    scopus 로고
    • Leptin induces proliferation and anti-apoptosis in human hepatocarci-noma cells by up-regulating cyclin D1 and down-regulating Bax via a janus kinase 2-linked pathway
    • doi:10.1677/ERC-06-0027
    • Chen C, Chang YC, Liu CL, Liu TP, Chang KJ, Guo IC (2007) Leptin induces proliferation and anti-apoptosis in human hepatocarci-noma cells by up-regulating cyclin D1 and down-regulating Bax via a janus kinase 2-linked pathway. Endocr Relat Cancer 14(2):513-529. doi:10.1677/ERC-06-0027
    • (2007) Endocr Relat Cancer , vol.14 , Issue.2 , pp. 513-529
    • Chen, C.1    Chang, Y.C.2    Liu, C.L.3    Liu, T.P.4    Chang, K.J.5    Guo, I.C.6
  • 3
    • 40949116308 scopus 로고    scopus 로고
    • Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors
    • doi:10.1634/stemcells.2007-0440
    • Cho RW, Wang X, Diehn M, Shedden K, Chen GY, Sherlock G, Gurney A, Lewicki J, Clarke MF (2008) Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors. Stem Cells 26(2):364-371. doi:10.1634/stemcells. 2007-0440
    • (2008) Stem Cells , vol.26 , Issue.2 , pp. 364-371
    • Cho, R.W.1    Wang, X.2    Diehn, M.3    Shedden, K.4    Chen, G.Y.5    Sherlock, G.6    Gurney, A.7    Lewicki, J.8    Clarke, M.F.9
  • 5
    • 4644251054 scopus 로고    scopus 로고
    • Serum leptin levels and body composition in postmenopausal women: Effects of hormone therapy
    • Di Carlo C, Tommaselli GA, Sammartino A, Bifulco G, Nasti A, Nappi C (2004) Serum leptin levels and body composition in postmenopausal women: effects of hormone therapy. Menopause 11(4):466-473
    • (2004) Menopause , vol.11 , Issue.4 , pp. 466-473
    • Di Carlo, C.1    Tommaselli, G.A.2    Sammartino, A.3    Bifulco, G.4    Nasti, A.5    Nappi, C.6
  • 7
    • 0031978142 scopus 로고    scopus 로고
    • Leptin, leptin receptors, and the control of body weight
    • discussion s54-s75
    • Friedman JM (1998) Leptin, leptin receptors, and the control of body weight. Nutr Rev 56(2 Pt 2):s38-s46; discussion s54-s75
    • (1998) Nutr Rev , vol.56 , Issue.2 PART 2
    • Friedman, J.M.1
  • 8
    • 0034987715 scopus 로고    scopus 로고
    • The adipocyte: A model for integration of endocrine and metabolic signaling in energy metabolism regulation
    • Fruhbeck G, Gomez-Ambrosi J, Muruzabal FJ, Burrell MA (2001) The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation. Am J Physiol Endocrinol Metab 280(6):E827-E847
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , Issue.6
    • Fruhbeck, G.1    Gomez-Ambrosi, J.2    Muruzabal, F.J.3    Burrell, M.A.4
  • 10
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, Barnes D, Peters G (1994) Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 54(7):1812-1817
    • (1994) Cancer Res , vol.54 , Issue.7 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3    Fisher, C.4    Bartek, J.5    Dickson, C.6    Barnes, D.7    Peters, G.8
  • 13
    • 0037146224 scopus 로고    scopus 로고
    • Leptin - A growth factor in normal and malignant breast cells and for normal mammary gland development
    • Hu X, Juneja SC, Maihle NJ, Cleary MP (2002) Leptin - a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 94(22):1704-1711
    • (2002) J Natl Cancer Inst , vol.94 , Issue.22 , pp. 1704-1711
    • Hu, X.1    Juneja, S.C.2    Maihle, N.J.3    Cleary, M.P.4
  • 14
    • 3042817487 scopus 로고    scopus 로고
    • Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    • doi:10.1158/1078-0432.CCR-03-0749
    • Ishikawa M, Kitayama J, Nagawa H (2004) Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 10(13):4325-4331. doi:10.1158/1078-0432.CCR-03-0749
    • (2004) Clin Cancer Res , vol.10 , Issue.13 , pp. 4325-4331
    • Ishikawa, M.1    Kitayama, J.2    Nagawa, H.3
  • 15
    • 73649115686 scopus 로고    scopus 로고
    • Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis
    • Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, Hinds PW (2010) Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell 17(1): 65-76
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 65-76
    • Jeselsohn, R.1    Brown, N.E.2    Arendt, L.3    Klebba, I.4    Hu, M.G.5    Kuperwasser, C.6    Hinds, P.W.7
  • 17
    • 78650417958 scopus 로고    scopus 로고
    • Leptin and leptin receptor expression in breast cancer
    • doi:10.4143/crt.2009.41.3.155
    • Kim HS (2009) Leptin and leptin receptor expression in breast cancer. Cancer Res Treat 41(3):155-163. doi:10.4143/crt.2009.41.3.155
    • (2009) Cancer Res Treat , vol.41 , Issue.3 , pp. 155-163
    • Kim, H.S.1
  • 19
    • 77954533434 scopus 로고    scopus 로고
    • Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: Preliminary results and therapeutic implications
    • doi:10.1007/s00109-010-0611-8
    • Maccio A, Madeddu C, Gramignano G, Mulas C, Floris C, Massa D, Astara G, Chessa P, Mantovani G (2010) Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications. J Mol Med. doi:10.1007/s00109-010-0611-8
    • (2010) J Mol Med.
    • Maccio, A.1    Madeddu, C.2    Gramignano, G.3    Mulas, C.4    Floris, C.5    Massa, D.6    Astara, G.7    Chessa, P.8    Mantovani, G.9
  • 20
    • 33644527562 scopus 로고    scopus 로고
    • High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels
    • doi:10.1002/ijc.21543
    • Miyoshi Y, Funahashi T, Tanaka S, Taguchi T, Tamaki Y, Shimomura I, Noguchi S (2006) High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels. Int J Cancer 118(6):1414-1419. doi:10.1002/ijc.21543
    • (2006) Int J Cancer , vol.118 , Issue.6 , pp. 1414-1419
    • Miyoshi, Y.1    Funahashi, T.2    Tanaka, S.3    Taguchi, T.4    Tamaki, Y.5    Shimomura, I.6    Noguchi, S.7
  • 21
    • 80052178858 scopus 로고    scopus 로고
    • Leptin and cancer: From cancer stem cells to metastasis
    • Park J, Scherer PE (2011) Leptin and cancer: from cancer stem cells to metastasis. Endocr Relat Cancer 18(4):C25-C29
    • (2011) Endocr Relat Cancer , vol.18 , Issue.4
    • Park, J.1    Scherer, P.E.2
  • 22
    • 54049111497 scopus 로고    scopus 로고
    • Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women
    • Phipps AI, Malone KE, Porter PL, Daling JR, Li CI (2008) Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women. Cancer Epidemiol Biomarkers Prev 17(8):2078-2086
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.8 , pp. 2078-2086
    • Phipps, A.I.1    Malone, K.E.2    Porter, P.L.3    Daling, J.R.4    Li, C.I.5
  • 23
    • 9444223845 scopus 로고    scopus 로고
    • Leptin as a novel profibrogenic cytokine in hepatic stellate cells: Mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
    • doi:10.1096/fj.04-1847fje04-1847fje
    • Saxena NK, Titus MA, Ding X, Floyd J, Srinivasan S, Sitaraman SV, Anania FA (2004) Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation. FASEB J 18(13):1612-1614. doi:10.1096/fj.04-1847fje04-1847fje
    • (2004) FASEB J , vol.18 , Issue.13 , pp. 1612-1614
    • Saxena, N.K.1    Titus, M.A.2    Ding, X.3    Floyd, J.4    Srinivasan, S.5    Sitaraman, S.V.6    Anania, F.A.7
  • 24
    • 34250315764 scopus 로고    scopus 로고
    • Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3
    • Saxena NK, Vertino PM, Anania FA, Sharma D (2007) leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. J Biol Chem 282(18): 13316-13325
    • (2007) J Biol Chem , vol.282 , Issue.18 , pp. 13316-13325
    • Saxena, N.K.1    Vertino, P.M.2    Anania, F.A.3    Sharma, D.4
  • 26
    • 84858019563 scopus 로고    scopus 로고
    • Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires beta-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways
    • doi: 10.1074/jbc.M111.322800
    • Yan D, Avtanski D, Saxena NK, Sharma D (2012) Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires beta-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways. J Biol Chem 287(11):8598-8612. doi: 10.1074/jbc.M111.322800
    • (2012) J Biol Chem , vol.287 , Issue.11 , pp. 8598-8612
    • Yan, D.1    Avtanski, D.2    Saxena, N.K.3    Sharma, D.4
  • 27
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • doi:10.1038/3508250035082500
    • Yu Q, Geng Y, Sicinski P (2001) Specific protection against breast cancers by cyclin D1 ablation. Nature 411(6841):1017-1021. doi:10.1038/ 3508250035082500
    • (2001) Nature , vol.411 , Issue.6841 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 28
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • doi:10.1038/372425a0
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372(6505):425-432. doi:10.1038/372425a0
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 29
    • 80052155796 scopus 로고    scopus 로고
    • Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival
    • Zheng Q, Dunlap SM, Zhu J, Downs-Kelly E, Rich J, Hursting SD, Berger NA, Reizes O (2011) Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. Endocr Relat Cancer 18(4):491-503
    • (2011) Endocr Relat Cancer , vol.18 , Issue.4 , pp. 491-503
    • Zheng, Q.1    Dunlap, S.M.2    Zhu, J.3    Downs-Kelly, E.4    Rich, J.5    Hursting, S.D.6    Berger, N.A.7    Reizes, O.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.