Single impact cartilage trauma and TNF-α: Interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches

International Journal of Molecular Medicine

Volumn 30, Issue 5, 2012, Pages 1225-1232

  Hogrefe, Cathrin ^a   Joos, Helga ^a   Maheswaran, Vennila ^a   Dürselen, Lutz ^a   Ignatius, Anita ^a   Brenner, Rolf E ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Cartilage; Cell death; Nitric oxide; Prostaglandins; TNF ; Trauma

Indexed keywords

AGGRECANASE 1; AGGRECANASE 2; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; OSTEOPROTEGERIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROTEOGLYCAN; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ARTICULAR CARTILAGE; BLUNT TRAUMA; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE INJURY; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; OSTEOARTHRITIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN DEGRADATION; SYNOVIAL FLUID;

AGED; APOPTOSIS; CARTILAGE, ARTICULAR; CELL SURVIVAL; CHONDROCYTES; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION; HUMANS; INTERLEUKIN-6; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MATRIX METALLOPROTEINASE 1; MIDDLE AGED; NITRATES; NITRIC OXIDE SYNTHASE TYPE II; OSTEOARTHRITIS, KNEE; OSTEOPROTEGERIN; PROSTAGLANDIN D2; RANK LIGAND; TISSUE CULTURE TECHNIQUES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866625694     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.1112     Document Type: Article

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