Late-onset increases in oxidative stress and other tumorigenic activities and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic

Toxicological Sciences

Volumn 129, Issue 2, 2012, Pages 293-304

  Nohara, Keiko ^a,b   Tateishi, Yukiyo ^a   Suzuki, Takehiro ^a   Okamura, Kazuyuki ^a,b   Murai, Hikari ^a   Takumi, Shota ^a   Maekawa, Fumihiko ^a   Nishimura, Noriko ^a   Kobori, Masuko ^c   Ito, Takaaki ^d  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Arsenic; Gestational exposure; Ha ras; Hepatic tumor; HO 1; L1 retrotransposon

Indexed keywords

ARSENIC; HEME OXYGENASE 1; HISTONE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; HISTONE MODIFICATION; HISTOPATHOLOGY; LIPID METABOLISM; LIPID TRANSPORT; LIVER TUMOR; MALE; MOUSE; NONHUMAN; ONCOGENE H RAS; OXIDATIVE STRESS; PRENATAL EXPOSURE; REAL TIME POLYMERASE CHAIN REACTION; RETROPOSON; UPREGULATION;

ANIMALS; ARSENIC; CARCINOGENS; CHROMATIN IMMUNOPRECIPITATION; FEMALE; GENES, RAS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED C3H; MUTATION; OXIDATIVE STRESS; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION;

MUS;

EID: 84866623629     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs203     Document Type: Article

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