Lemierre's syndrome due to Fusobacterium necrophorum

The Lancet Infectious Diseases

Volumn 12, Issue 10, 2012, Pages 808-815

  Kuppalli, Krutika ^a   Livorsi, Daniel ^b   Talati, Naasha J ^c   Osborn, Melissa ^d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b INDIANA UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d EMORY UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; C REACTIVE PROTEIN; CEFTRIAXONE; CLINDAMYCIN; CORTICOSTEROID; IBUPROFEN; METRONIDAZOLE;

ADULT; ANTIBIOTIC THERAPY; BLOOD CULTURE; BRAIN ABSCESS; CASE REPORT; CHILL; CORTICOSTEROID THERAPY; DRUG TREATMENT FAILURE; DYSPNEA; FACE EDEMA; FEVER; FUSOBACTERIUM NECROPHORUM; HUMAN; LEMIERRE SYNDROME; LYMPHADENOPATHY; MALAISE; MALE; NEUROPATHOLOGY; NIGHT SWEAT; OUTCOME ASSESSMENT; PLEURA EFFUSION; PNEUMONIA; PRIORITY JOURNAL; REVIEW; SORE THROAT; THROMBOPHLEBITIS; TONSILLITIS; VIRAL PHARYNGITIS; WEIGHT REDUCTION;

ADOLESCENT; ANTI-BACTERIAL AGENTS; BRAIN ABSCESS; FUSOBACTERIUM NECROPHORUM; HUMANS; LEMIERRE SYNDROME; MAGNETIC RESONANCE IMAGING; MALE; PLEURAL EFFUSION;

EID: 84866619160     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(12)70089-0     Document Type: Review

References (84)

1. Courmont P, Cade A Sur une septic-pyohemie de l'homme stimulant la peste et cause par un streptobacille anaerobie. Archives de Med Exp et d'Anat Path 1900, 4.
2. Vohra A, Saiz E, Ratzan KR A young woman with a sore throat, septicaemia, and respiratory failure. Lancet 1997, 350:928.
3. Lemierre A On certain septicemias due to anaerobic organisms. Lancet 1936, 227:701-703.
4. Riordan T Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome. Clin Microbiol Rev 2007, 20:622-659.
5. Hagelskjaer Kristensen L, Prag J Lemierre's syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis 2008, 27:779-789.
6. Armstrong AW, Spooner K, Sanders JW Lemierre's syndrome. Curr Infect Dis Rep 2000, 2:168-173.
7. Brazier JS, Hall V, Yusuf E, Duerden BI Fusobacterium necrophorum infections in England and Wales 1990-2000. J Med Microbiol 2002, 51:269-272.
8. Hagelskjaer LH, Prag J, Malczynski J, Kristensen JH Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark 1990-1995. Eur J Clin Microbiol Infect Dis 1998, 17:561-565.
9. Leugers CM, Clover R Lemierre syndrome: postanginal sepsis. J Am Board Fam Pract 1995, 8:384-391.
10. Sinave CP, Hardy GJ, Fardy PW The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. Medicine (Baltimore) 1989, 68:85-94.
11. Ramirez S, Hild TG, Rudolph CN, et al. Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital. Pediatrics 2003, 112:e380.
12. Freeman JL, Jekel JF, Freeman DH Changes in age and sex specific tonsillectomy rates: United States, 1970-1977. Am J Public Health 1982, 72:488-491.
13. McCaig LF, Besser RE, Hughes JM Trends in antimicrobial prescribing rates for children and adolescents. JAMA 2002, 287:3096-3102.
14. Hagelskjaer Kristensen L, Prag J Human necrobacillosis, with emphasis on Lemierre's syndrome. Clin Infect Dis 2000, 31:524-532.
15. Batty A, Wren MW Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs. Br J Biomed Sci 2005, 62:66-70.
16. Moreno S, García Altozano J, Pinilla B, et al. Lemierre's disease: postanginal bacteremia and pulmonary involvement caused by Fusobacterium necrophorum. Rev Infect Dis 1989, 11:319-324.
17. Jousimies-Somer H, Summanen P, Finegole S Bacteriodes, porphyromonas, prevotella, fusobacterium, and other anaerobic gram-negative bacteria 1995, 603-620. American Society for Microbiology, Washington, DC. P. Murray (Ed.).
18. Langworth BF Fusobacterium necrophorum: its characteristics and role as an animal pathogen. Bacteriol Rev 1977, 41:373-390.
19. Tan ZL, Nagaraja TG, Chengappa MM Biochemical and biological characterization of ruminal Fusobacterium necrophorum. FEMS Microbiol Lett 1994, 120:81-86.
20. Hughes CE, Spear RK, Shinabarger CE, Tuna IC Septic pulmonary emboli complicating mastoiditis: Lemierre's syndrome revisited. Clin Infect Dis 1994, 18:633-635.
21. Chirinos JA, Lichtstein DM, Garcia J, Tamariz LJ The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine (Baltimore) 2002, 81:458-465.
22. Ieven M, Vael K, De Mayer M, De Schepper A, Pattyn S Three cases of Fusobacterium necrophorum septicemia. Eur J Clin Microbiol Infect Dis 1993, 12:705-706.
23. Smith GR, Barton SA, Wallace LM Further observations on enhancement of the infectivity of Fusobacterium necrophorum by other bacteria. Epidemiol Infect 1991, 106:305-310.
24. Alvarez A, Schreiber JR Lemierre's syndrome in adolescent children-anaerobic sepsis with internal jugular vein thrombophlebitis following pharyngitis. Pediatrics 1995, 96:354-359.
25. Dagan R, Powell KR Postanginal sepsis following infectious mononucleosis. Arch Intern Med 1987, 147:1581-1583.
26. Adams J, Capistrant T, Crossley K, Johanssen R, Liston S Fusobacterium necrophorum septicemia. JAMA 1983, 250:35.
27. Stenfors LE, Bye HM, Räisänen S, Myklebust R Bacterial penetration into tonsillar surface epithelium during infectious mononucleosis. J Laryngol Otol 2000, 114:848-852.
28. Garcia MM, Alexander DC, McKay KA Biological characterization of Fusobacterium necrophorum. Cell fractions in preparation for toxin and immunization studies. Infect Immun 1975, 11:609-616.
29. Forrester LJ, Campbell BJ, Berg JN, Barrett JT Aggregation of platelets by Fusobacterium necrophorum. J Clin Microbiol 1985, 22:245-249.
30. Kanoe M, Yamanaka M, Inoue M Effects of Fusobacterium necrophorum on the mesenteric microcirculation of guinea pigs. Med Microbiol Immunol (Berl) 1989, 178:99-104.
31. Hofstad T Pathogenicity of anaerobic gram-negative rods: possible mechanisms. Rev Infect Dis 1984, 6:189-199.
32. Lustig LR, Cusick BC, Cheung SW, Lee KC Lemierre's syndrome: two cases of postanginal sepsis. Otolaryngol Head Neck Surg 1995, 112:767-772.
33. Goldhagen J, Alford BA, Prewitt LH, Thompson L, Hostetter MK Suppurative thrombophlebitis of the internal jugular vein: report of three cases and review of the pediatric literature. Pediatr Infect Dis J 1988, 7:410-414.
34. Chow AW Life-threatening infections of the head and neck. Clin Infect Dis 1992, 14:991-1002.
35. Morizono S, Enjoji M, Sonoda N, et al. Lemierre's syndrome: Porphyromonas asaccharolytica as a putative pathogen. Intern Med 2005, 44:350-353.
36. Carlson ER, Bergamo DF, Coccia CT Lemierre's syndrome: two cases of a forgotten disease. J Oral Maxillofac Surg 1994, 52:74-78.
37. Nadir NA, Stone MB, Chao J Diagnosis of Lemierre's syndrome by bedside sonography. Acad Emerg Med 2010, 17:E9-10.
38. Albertyn LE, Alcock MK Diagnosis of internal jugular vein thrombosis. Radiology 1987, 162:505-508.
39. Vogel LC, Boyer KM Metastatic complications of Fusobacterium necrophorum sepsis. Two cases of Lemierre's postanginal septicemia. Am J Dis Child 1980, 134:356-358.
40. Bader-Meunier B, Pinto G, Tardieu M, Pariente D, Bobin S, Dommergues JP Mastoiditis, meningitis and venous sinus thrombosis caused by Fusobacterium necrophorum. Eur J Pediatr 1994, 153:339-341.
41. Spencer CH, Slusher CW, Sanders CV, Aldridge KE Fusobacterium necrophorum sepsis with cerebral infarction. South Med J 1989, 82:1040-1043.
42. Jones TH, Bergvall V, Bradshaw JP Carotid artery stenoses and thrombosis secondary to cavernous sinus thromboses in Fusobacterium necrophorum meningitis. Postgrad Med J 1990, 66:747-750.
43. Stokroos RJ, Manni JJ, de Kruijk JR, Soudijn ER Lemierre syndrome and acute mastoiditis. Arch Otolaryngol Head Neck Surg 1999, 125:589-591.
44. Marangos MN, Fuchs-Ertman DA, Kourea HP, et al. Cerebral infarct and adult respiratory distress syndrome in a patient with postanginal sepsis. Clin Microbiol Infect 2000, 6:337-339.
45. Agarwal R, Arunachalam PS, Bosman DA Lemierre's syndrome: a complication of acute oropharyngitis. J Laryngol Otol 2000, 114:545-547.
46. Hope A, Bleach N, Ghiacy S Lemierre's syndrome as a consequence of acute supraglottitis. J Laryngol Otol 2002, 116:216-218.
47. Jaremko JL, Kirton A, Brenner JL A 12-year-old girl with pharyngitis, meningitis and sinovenous thrombosis. CMAJ 2003, 169:811-812.
48. Figueras Nadal C, Creus A, Beatobe S, Moraga F, Pujol M, Vazquez E Lemierre syndrome in a previously healthy young girl. Acta Paediatr 2003, 92:631-633.
49. Bentham JR, Pollard AJ, Milford CA, Anslow P, Pike MG Cerebral infarct and meningitis secondary to Lemierre's syndrome. Pediatr Neurol 2004, 30:281-283.
50. Touitou D, Deltour S, Bonneville F, et al. Hemiplegia in Lemierre syndrome: a neuroimaging strategy. Eur J Neurol 2006, 13:424-426.
51. Park D, Rezajooi K, Sabin I Lemierre's syndrome: an unusual manifestation of spinal infection. J Bone Joint Surg Br 2006, 88:261-262.
52. Westhout F, Hasso A, Jalili M, et al. Lemierre syndrome complicated by cavernous sinus thrombosis, the development of subdural empyemas, and internal carotid artery narrowing without cerebral infarction. Case report. J Neurosurg 2007, 106(suppl):53-56.
53. van Dijk EJ, van Swieten JC, Koudstaal PJ Meningitis, cranial nerve palsies and bilateral cerebral infarcts: a neurological variant of Lemierre's syndrome. J Neurol 2008, 255:1588-1589.
54. Brown LM, Wallwork B Lemierre's-the sinister sore throat. J Laryngol Otol 2007, 121:692-694.
55. Goyal MK, Kumar G, Burger R Necrobacillosis resulting in isolated carotid thrombosis and massive stroke: a unique Lemierre variant?. J Neurol Sci 2009, 287:108-110.
56. Gilbert JD, Warner MS, Byard RW Lemierre syndrome and unexpected death in childhood. J Forensic Leg Med 2009, 16:478-481.
57. Vincent QB, Labedan I, Madhi F Lemierre syndrome with meningo-encephalitis, severe cerebral artery stenosis, and focal neurological symptoms. J Pediatr 2010, 157:345.
58. Chacko EM, Krilov LR, Patten W, Lee PJ Lemierre's and Lemierre's-like syndromes in association with infectious mononucleosis. J Laryngol Otol 2010, 124:1257-1262.
59. Ridgway JM, Parikh DA, Wright R, et al. Lemierre syndrome: a pediatric case series and review of literature. Am J Otolaryngol 2010, 31:38-45.
60. Teng HW, Chen CY, Chen HC, Chung WT, Lee WS Fusobacterium septicemia complicated by cerebral subdural and epidural empyemas: a rare case of Lemierre syndrome. J Emerg Med 2010, published online June 19. 10.1016/j.jemermed.2010.04.033.
61. Aouad R, Melkane A, Rassi S Lemierre syndrome: unusual cause and presentation. Pediatr Emerg Care 2010, 26:376-377.
62. Peer Mohamed B, Carr L Neurological complications in two children with Lemierre syndrome. Dev Med Child Neurol 2010, 52:779-781.
63. Habek M, Petravić D, Ozretić D, Brinar VV Neurological picture. Horner syndrome due to jugular vein thrombosis (Lemierre syndrome). J Neurol Neurosurg Psychiatry 2008, 79:293.
64. Shibasaki Warabi Y, Yoshikawa H, Idezuka J, Yamazaki M, Onishi Y Cerebral infarctions and brain abscess due to Lemierre syndrome. Intern Med 2005, 44:653-656.
65. Repanos C, Chadha NK, Griffiths MV Sigmoid sinus thrombosis secondary to Lemierre's syndrome. Ear Nose Throat J 2006, 85:98-101.
66. Kahn JB, Baharestani S, Beck HC, et al. Orbital dissemination of Lemierre syndrome from gram-positive septic emboli. Ophthal Plast Reconstr Surg 2011, 27:e67-e68.
67. Thompson M, Awonuga AO, Bell J, Ray C, Awonuga MT, Helfgott A Lemierre's syndrome complicating pregnancy. Infect Dis Obstet Gynecol 2007, 2007:68084.
68. Maalikjy Akkawi N, Borroni B, Magoni M, Vignolo LA, Padovani A Lemierre's syndrome complicated by carotid thrombosis. Neurol Sci 2001, 22:403-404.
69. Gilbert JD, Warner MS, Byard RW Lemierre syndrome and unexpected death in childhood. J Forensic Leg Med 2009, 16:478-481.
70. Guerrero IC, Slap GB, MacGregor RR, Lawner P, Ruggeri S, Gennarelli T Anaerobic spinal epidural abscess. Case report. J Neurosurg 1978, 48:465-469.
71. Brook I Infections caused by beta-lactamase-producing Fusobacterium spp. in children. Pediatr Infect Dis J 1993, 12:532-533.
72. Nord CE, Heimdahl A, Tunér K Beta-lactamase producing anaerobic bacteria in the oropharynx and their clinical relevance. Scand J Infect Dis Suppl 1988, 57:50-54.
73. Freeman CD, Klutman NE, Lamp KC Metronidazole. A therapeutic review and update. Drugs 1997, 54:679-708.
74. Kowalsky SF, Echols RM, McCormick EM Comparative serum bactericidal activity of ceftizoxime/metronidazole, ceftizoxime, clindamycin, and imipenem against obligate anaerobic bacteria. J Antimicrob Chemother 1990, 25:767-775.
75. Kearney BP, Aweeka FT The penetration of anti-infectives into the central nervous system. Neurol Clin 1999, 17:883-900.
76. Bergeron MG, Robert J, Beauchamp D Pharmacodynamics of antibiotics in fibrin clots. J Antimicrob Chemother 1993, 31(suppl D):113-136.
77. Golpe R, Marín B, Alonso M Lemierre's syndrome (necrobacillosis). Postgrad Med J 1999, 75:141-144.
78. Bondy P, Grant T Lemierre's syndrome: what are the roles for anticoagulation and long-term antibiotic therapy?. Ann Otol Rhinol Laryngol 2008, 117:679-683.
79. Dessole S, Capobianco G, Arru A, Demurtas P, Ambrosini G Postpartum ovarian vein thrombosis: an unpredictable event: two case reports and review of the literature. Arch Gynecol Obstet 2003, 267:242-246.
80. Witlin AG, Sibai BM Postpartum ovarian vein thrombosis after vaginal delivery: a report of 11 cases. Obstet Gynecol 1995, 85:775-780.
81. Josey WE, Staggers SR Heparin therapy in septic pelvic thrombophlebitis: a study of 46 cases. Am J Obstet Gynecol 1974, 120:228-233.
82. Brown CE, Stettler RW, Twickler D, Cunningham FG Puerperal septic pelvic thrombophlebitis: incidence and response to heparin therapy. Am J Obstet Gynecol 1999, 181:143-148.
83. Karkos PD, Asrani S, Karkos CD, et al. Lemierre's syndrome: a systematic review. Laryngoscope 2009, 119:1552-1559.
84. Venglarcik J Lemierre's syndrome. Pediatr Infect Dis J 2003, 22:921-923.