Time-dependent aroma changes in breast milk after oral intake of a pharmacological preparation containing 1,8-cineole

Clinical Nutrition

Volumn 31, Issue 5, 2012, Pages 682-692

  Kirsch, Frauke ^a   Beauchamp, Jonathan ^b   Buettner, Andrea ^a,b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b FRAUNHOFER INSTITUTE FOR PROCESS ENGINEERING AND PACKAGING IVV   (Germany)

Author keywords

1,8 Cineole; Breath gas analysis; Human milk; Odorant transfer; Sensory analysis; Stable isotope dilution assay (SIDA)

Indexed keywords

CINEOLE;

AROMA; ARTICLE; BREAST MILK; BREATH ANALYSIS; EUCALYPTUS; HUMAN; HUMAN EXPERIMENT; ISOTOPE DILUTION ASSAY; MASS SPECTROMETRY; NORMAL HUMAN; PROTON TRANSFER REACTION MASS SPECTROMETRY; SENSORY ANALYSIS; TIME;

ADMINISTRATION, ORAL; ADULT; BREATH TESTS; CYCLOHEXANOLS; EUCALYPTUS; EXHALATION; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; ISOTOPE LABELING; MILK, HUMAN; MONOTERPENES; ODORS;

EID: 84866615433     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2012.02.002     Document Type: Article

References (27)

1. Mennella J.A., Beauchamp G.K. Maternal diet alters the sensory qualities of human-milk and the nurslings behavior. Pediatrics 1991, 88:737-744.
2. Mennella J.A., Beauchamp G.K. Beer, breast-feeding, and folklore. Dev Psychobiol 1993, 26:459-466.
3. Mennella J.A., Beauchamp G.K. Experience with a flavor in mother's milk modifies the infant's acceptance of flavored cereal. Dev Psychobiol 1999, 35:197-203.
4. Hausner H., Bredie W.L.P., Mølgaard C., Petersen M.A., Møller P. Differential transfer of dietary flavour compounds into human breast milk. Physiol Behav 2008, 95:118-124.
5. Hausner H., Nicklaus S., Issanchou S., Mølgaard C., Møller P. Breastfeeding facilitates acceptance of a novel dietary flavour compound. Clin Nutr 2010, 29:141-148.
6. Soussignan R., Schaal B., Marlier L., Jiang T. Facial and autonomic responses to biological and artificial olfactory stimuli in human neonates: re-examining early hedonic discrimination of odors. Physiol Behav 1997, 62:745-758.
7. Nishitani S., Miyamura T., Tagawa M., Sumi M., Takase R., Doi H., et al. The calming effect of a maternal breast milk odor on the human newborn infant. Neurosci Res 2009, 63:66-71.
8. Schaal B., Hummel T., Soussignan R. Olfaction in the fetal and premature infant: functional status and clinical implications. Clin Perinatol 2004, 31:261-285.
9. Mennella J.A., Jagnow C.P., Beauchamp G.K. Prenatal and postnatal flavor learning by human infants. Pediatrics 2001, 107:e88.
10. Maier A.S., Chabanet C., Schaal B., Leathwood P.D., Issanchou S.N. Breastfeeding and experience with variety early in weaning increase infants' acceptance of new foods for up to two months. Clin Nutr 2008, 27:849-857.
11. De Vincenzi M., Silano M., De Vincenzi A., Maialetti F., Scazzocchio B. Constituents of aromatic plants: eucalyptol. Fitoterapia 2002, 73:269-275.
12. Beauchamp J., Kirsch F., Buettner A. Real-time breath gas analysis for pharmacokinetics: monitoring exhaled breath by on-line proton-transfer-reaction mass spectrometry after ingestion of eucalyptol-containing capsules. J Breath Res 2010, 4:026006.
13. Spitzer J., Buettner A. Characterization of aroma changes in human milk during storage at -19 °C. Food Chem 2010, 120:240-246.
14. Engel W., Bahr W., Schieberle P. Solvent assisted flavour evaporation - a new and versatile technique for the careful and direct isolation of aroma compounds from complex food matrices. Eur Food Res Technol 1999, 209:237-241.
15. Schieberle P., Grosch W. Quantitative analysis of aroma compounds in wheat and rye bread crusts using a stable isotope-dilution assay. J Agric Food Chem 1987, 35:252-257.
16. Almeida A.M., Castel-Branco M.M., Falcao A.C. Linear regression for calibration lines revisited: weighting schemes for bioanalytical methods. J Chrom B 2002, 774:215-222.
17. Kováts E. Gas-chromatographische Charakterisierung organischer Verbindungen. Teil 1: Retentionsindices aliphatischer Halogenide, Alkohole, Aldehyde und Ketone. Helv Chim Acta 1958, 41:1915-1932.
18. McManaman J.L., Neville M.C. Mammary physiology and milk secretion. Adv Drug Deliv Rev 2003, 55:629-641.
19. Buettner A. Aroma release and perception during consumption of food taking into account physiological aspects. Thesis of habilitation. Verlag Dr Hut; Munich, Germany. 2007.
20. Linzell J.L., Peaker M. Mechanism of milk secretion. Physiol Rev 1971, 51:564-592.
21. Désage M., Schaal B., Soubeyrand J., Orgeur P., Brazier J.-L. Gas chromatographic-mass spectrometric method to characterise the transfer of dietary odorous compounds into plasma and milk. J Chromatogr B: Biomed Sci Appl 1996, 678:205-210.
22. Mennella J.A. Mother's milk: a medium for early flavor experiences. J Hum Lact 1995, 11:39-45.
23. Czerny M., Christlbauer M., Christlbauer M., Fischer A., Granvogl M., Hammer M., et al. Re-investigation on odour thresholds of key food aroma compounds and development of an aroma language based on odour qualities of defined aqueous odorant solutions. Eur Food Res Technol 2008, 228:265-273.
24. Jagella T., Grosch W. Flavour and off-flavour compounds of black and white pepper (Piper nibrum L.) III. desirable and undesirable odorants of white pepper. Eur Food Res Technol 1999, 209:27-31.
25. Horst K., Rychlik M. Quantification of 1,8-cineole and of its metabolites in humans using stable isotope dilution assays. Mol Nutr Food Res 2010, 54:1515-1529.
26. Zeller A., Rychlik M. Character impact odorants of fennel fruits and fennel tea. J Agric Food Chem 2006, 54:3686-3692.
27. Opinion of the scientific committee on food on eucalyptol 2002.