Homeostasis of the drosophila adult retina by actin-capping protein and the hippo pathway

Communicative and Integrative Biology

Volumn 4, Issue 5, 2011, Pages 612-615

  Brás Pereira, Catarina ^a   Zhang, Tianyi ^b   Pignoni, Francesca ^b,c   Janody, Florence ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^c SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

Actin cytoskeleton; Capping protein; Drosophila adult retina; Expanded; Fat; Hippo signaling pathway; Neuronal degeneration; Yorkie

Indexed keywords

EID: 84866606725     PISSN: 19420889     EISSN: 19420889     Source Type: Journal    
DOI: 10.4161/cib.16853     Document Type: Article

References (27)

1. Wu S, Huang J, Dong J, Pan D. hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 2003; 114:445-56.
2. Pantalacci S, Tapon N, Leopold P. The Salvador partner Hippo promotes apoptosis and cell cycle exit in Drosophila. Nat Cell Biol 2003; 5:921-7.
3. Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, et al. salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 2002; 110:467-78.
4. Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G. Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat Cell Biol 2003; 5:914-20.
5. Lai ZC, Wei X, Shimizu T, Ramos E, Rohrbaugh M, Nikolaidis N, et al. Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 2005; 120:675-85.
6. Wei X, Shimizu T, Lai ZC. Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J 2007; 26:1772-81.
7. Oh H, Reddy BV, Irvine KD. Phosphorylationindependent repression of Yorkie in Fat-Hippo signaling. Dev Biol 2009; 335:188-97.
8. Huang J, Wu S, Barrera J, Matthews K, Pan D. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 2005; 122:421-34.
9. Oh H, Irvine KD. In vivo regulation of Yorkie phosphorylation and localization. Development 2008; 135:1081-8.
10. Reddy BV, Irvine KD. The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development 2008; 135:2827-38.
11. Napoletano F, Occhi S, Calamita P, Volpi V, Blanc E, Charroux B, et al. Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat. EMBO J 2011; 30:945-58.
12. Mikeladze-Dvali T, Wernet MF, Pistillo D, Mazzoni EO, Teleman AA, Chen YW, et al. The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. Cell 2005; 122:775-87.
13. Dutta S, Baehrecke EH. Warts is required for PI3Kregulated growth arrest, autophagy and autophagic cell death in Drosophila. Curr Biol 2008; 18:1466-75.
14. Grusche FA, Richardson HE, Harvey KF. Upstream regulation of the hippo size control pathway. Curr Biol 2010; 20:574-82.
15. Halder G, Johnson RL. Hippo signaling: growth control and beyond. Development 2010; 138:9-22.
16. Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, et al. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signaling to regulate cell proliferation and apoptosis. Nat Cell Biol 2006; 8:27-36.
17. Bryant PJ, Huettner B, Held LI Jr, Ryerse J, Szidonya J. Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila. Dev Biol 1988; 129:541-54.
18. Milton CC, Zhang X, Albanese NO, Harvey KF. Differential requirement of Salvador-Warts-Hippo pathway members for organ size control in Drosophila melanogaster. Development 137:735-43.
19. Fernandez BG, Gaspar P, Bras-Pereira C, Jezowska B, Rebelo SR, Janody F. Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development 2011; 138:2337-46.
20. Delalle I, Pfleger CM, Buff E, Lueras P, Hariharan IK. Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration. Genetics 2005; 171:1757-65.
21. Johnson RI, Seppa MJ, Cagan RL. The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J Cell Biol 2008; 180:1191-204.
22. Cooper JA, Sept D. New insights into mechanism and regulation of actin capping protein. Int Rev Cell Mol Biol 2008; 267:183-206.
23. Sansores-Garcia L, Bossuyt W, Wada KI, Yonemura S, Tao C, Sasaki H, et al. Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J 2011; 30:2325-35.
24. wafl/cip1stability. Mol Cell Biol 2009; 29:6380-90.
25. Das Thakur M, Feng Y, Jagannathan R, Seppa MJ, Skeath JB, Longmore GD. Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. Curr Biol 20:657-62.
26. Freeman M. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 1996; 87:651-60.
27. Zhang T, Ranade S, Cai CQ, Clouser C, Pignoni F. Direct control of neurogenesis by selector factors in the fly eye: regulation of atonal by Ey and So. Development 2006; 133:4881-9.