Crystal structure and functional characterization of the complement regulator mannose-binding lectin (MBL)/ficolin-associated protein-1 (MAP-1)

Journal of Biological Chemistry

Volumn 287, Issue 39, 2012, Pages 32913-32921

  Skjoedt, Mikkel Ole ^a   Roversi, Pietro ^b   Hummelshøj, Tina ^a   Palarasah, Yaseelan ^a,c   Rosbjerg, Anne ^a   Johnson, Steven ^b   Lea, Susan M ^b   Garred, Peter ^a  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DIRECT INTERACTIONS; DOSE-DEPENDENT; FUNCTIONAL CHARACTERIZATION; HEAVY CHAIN; HOMODIMERS; INHIBITORY EFFECT; LIGAND BINDING; MULTIANGLE LASER LIGHT SCATTERING; NON-ENZYMATIC; PLASMA PROTEIN; SERINE PROTEASE; STRUCTURAL ASPECTS;

AMINO ACIDS; MOLECULES; PATHOGENS;

PROTEINS;

CALCIUM; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C9; COMPLEMENT FACTOR; DIMER; FICOLIN; FICOLIN 3; HOMODIMER; MANNOSE BINDING LECTIN; MAP 1 PROTEIN; MASP 3 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; FEMALE; LIGAND BINDING; LIGHT SCATTERING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

ALTERNATIVE SPLICING; ANIMALS; CHO CELLS; COMPLEMENT C3; COMPLEMENT C9; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; CRICETINAE; CRICETULUS; GLYCOPROTEINS; HUMANS; LECTINS; MANNOSE-BINDING LECTIN; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MODELS, MOLECULAR; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84866528696     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.386680     Document Type: Article

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