Recombinant expression of human mannan-binding lectin

International Immunopharmacology

Volumn 1, Issue 4, 2001, Pages 677-687

  Vorup Jensen, Thomas ^a   Sørensen, Esben S ^a   Jensen, Uffe B ^a   Schwaeble, Wilhelm ^b   Kawasaki, Toshisuke ^c   Ma, Yong ^c   Uemura, Kazuhide ^c   Wakamiya, Nobutaka ^d   Suzuki, Yasuhiko ^d   Jensen, Thomas G ^a   Takahashi, Kazue ^e   Ezekowitz, R Alan B ^e   Thiel, Steffen ^a   Jensenius, Jens Chr ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c KYOTO UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Carbohydrate affinity chromatography; Complement deficiency; Structural and functional comparison recombinant mannan binding lectins

Indexed keywords

MANNAN BINDING LECTIN;

ANIMAL CELL; ARTICLE; CHO CELL; COMPLEMENT DEFICIENCY; COMPLEMENT DEPOSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE COMPLEX DISEASE; IMMUNE DEFICIENCY; IMMUNITY; LIVER CELL; MYELOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

CARRIER PROTEINS; COLLECTINS; HUMANS; RECOMBINANT PROTEINS;

EID: 0035105053     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(00)00052-7     Document Type: Article

References (47)

1. Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene
2. MASP-2, the C3 convertase generating protease of the MBL complement activating pathway
3. A second serine protease associated with mannan-binding lectin that activates complement
4. Distinct pathways of MBL- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MASP-2
5. Identical point mutation leading to low levels of mannose binding protein and poor C3b mediated opsonisation in Chinese and Caucasian populations
6. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene
7. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein
8. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein
9. Mannan-binding lectin deficiency is associated with unexplained recurrent miscarriage
10. Mannose-binding lectin (MBL) in health and disease
11. Association of variant alleles of mannose binding lectin with severity of pulmonary disease in cystic fibrosis: Cohort study
12. Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
13. Mannose-binding protein gene polymorphism in systemic lupus erythematosus
14. Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus
15. Association of systemic lupus erythematosus with promoter polymorphisms of the mannose-binding lectin gene
16. Two edged role of mannose binding lectin in rheumatoid arthritis: A cross sectional study
17. The association of variant mannose-binding lectin genotypes with radiographic outcome in rheumatoid arthritis
18. Mannose-binding lectin and rheumatoid arthritis in southern Chinese
19. A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins
20. A parallel three stranded α-helical bundle at the nucleation site of collagen triple-helix formation
21. Distinct physicochemical characteristics of human mannose-binding protein expressed by individuals of differing genotype
22. 2 complex, of the classical pathway of complement without involvement of C1q
23. Oligomeric structures required for complement activation of serum mannan-binding proteins
24. Structure of a C-type mannose-binding protein complexed with an oligosaccharide
25. Characterization of truncated human mannan-binding protein (MBP) expressed in Escherichia coli
26. Structural and functional roles of the amino-terminal region and collagen-like domain of human serum mannan-binding protein
27. Distinct and overlapping functions of allelic forms for human mannose-binding protein
28. Role of the collagen-like domain of the human serum mannan-binding protein in the activation of complement and the secretion of this lectin
29. The Gly→Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease
30. The human mannose-binding protein function as an opsonin
31. High-level effective production of human mannan-binding lectin (MBL) in Chinese hamster ovary (CHO) cells
32. Functional expression of human mannan-binding proteins (MBPs) in human hepatoma cell lines infected by recombinant vaccinia virus: Post-translational modification, molecular assembly, and differentiation of serum an liver MBP
33. Characterization studies on a new lectin found in seeds of Vicia ervilia
34. Characterization of the carbohydrate fragments obtained from Saccharomyces cerevisiae mannan by alkaline degradation
35. A rainbow trout lectin with multimeric structure
36. Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19
37. A simple modification of Blum's silver stain method allows for 30 minute detection of proteins in polyacrylamide gels
38. Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease
39. Amino acid analysis: Determination of cysteine plus half-cysteine in proteins after hydrochloric acid hydrolysis with a disulfide compound as additive
40. Reconstitution of opsonizing activity by infusion of mannan-binding lectin (MBL) to MBL-deficient humans
41. Small-scale preparation of complement components C3 and C4
42. Utilization of an Epstein-Barr virus replicon as a eukaryotic expression vector
43. Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA
44. RNA travel: Tracks from DNA to cytoplasm
45. Glycosphingolipid-binding specificity of the mannose-binding protein from human sera
46. The level of mannan-binding protein regulates the binding of complement-derived opsonins to mannan and zymosan at low serum concentrations