The many facets of procalcitonin in the critically ill population

Critical Care Medicine

Volumn 40, Issue 10, 2012, Pages 2903-2905

  Japiassu, Andre Miguel ^a   Bozza, Fernando A ^a,b  

^a Central Hospital of Rio de Janeiro   (Brazil)

^b D OR INSTITUTE FOR RESEARCH AND EDUCATION IDOR   (Brazil)

Author keywords

critical care; infection; procalcitonin; sepsis; shock

Indexed keywords

PROCALCITONIN;

CALCITONIN BLOOD LEVEL; CRITICALLY ILL PATIENT; DISEASE ASSOCIATION; DISEASE SEVERITY; EDITORIAL; GRAM NEGATIVE INFECTION; GRAM POSITIVE INFECTION; HUMAN; INFLAMMATION; INTENSIVE CARE UNIT; LENGTH OF STAY; PERITONITIS; PNEUMONIA; PRIORITY JOURNAL; SHOCK;

CALCITONIN; CRITICAL ILLNESS; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; PROTEIN PRECURSORS;

EID: 84866526842     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182631e56     Document Type: Editorial

References (15)

1. Gerlach H, Toussaint S: Sensitive, spe-cifc, predictive statistical basics: How to use biomarkers. Crit Care Clin 2011; 27:215-227
2. Reinhart K, Meisner M: Biomarkers in the critically ill patient: Procalcitonin. Crit Care Clin 2011; 27:253-263
3. Aouif A, Piriou V, Bastien O, et al: Usefulness of procalcitonin for diagnosis of infection in cardiac surgical patients. Crit Care Med 2000; 28:3171-3176
4. Rau B, Steinbach G, Baumgart K, et al: The clinical value of procalcitonin in the prediction of infected necrosis in acute pancreatitis. Intensive Care Med 2000; 26(Suppl 2):S159-S164 (Pubitemid 30186575)
5. Póvoa P, Coelho L, Almeida E, et al: Early identifcation of intensive care unit-acquired infections with daily monitoring of C-reactive protein: A prospective observational study. Crit Care 2006; 10:R63
6. Coelho LM, Salluh JI, Soares M, et al: Patterns of C-reactive protein RATIO response in severe community-acquired pneumonia: A cohort study. Crit Care 2012; 16:R53
7. Harbarth S, Holeckova K, Froidevaux C, et al; Geneva Sepsis Network: Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001; 164:396-402 (Pubitemid 32778205)
8. Clec'h C, Ferriere F, Karoubi P, et al: Diagnostic and prognostic value of procalcitonin in patients with septic shock. Crit Care Med 2004; 32:1166-1169. (Pubitemid 38620986)
9. Christ-Crain M, Stolz D, Bingisser R, et al: Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: A randomized trial. Am J Respir Crit Care Med 2006; 174:84-93 (Pubitemid 43955248)
10. Peters R P, Twisk JW, van Agtmael MA, et al: The role of procalcitonin in a decision tree for prediction of bloodstream infection in febrile patients. Clin Microbiol Infect 2006; 12:1207-1213 (Pubitemid 44762523)
11. Reynolds SC, Shorr AF, Muscedere J, et al: Longitudinal changes in procalci tonin in a heterogenous group of critically ill patients. Crit Care Med 2012; 40:2781-2787
12. Cinel I, Opal SM: Molecular biology of infam-mation and sepsis: A primer. Crit Care Med 2009; 37:291-304
13. Liappis AP, Gibbs KW, Nylen ES, et al: Exogenous procalcitonin evokes a pro-infammatory cytokine response. Infamm Res 2011; 60:203-207
14. Charles PE, Ladoire S, Snauwaert A, et al: Impact of previous sepsis on the accuracy of procalcitonin for the early diagnosis of blood stream infection in critically ill patients. BMC Infect Dis 2008; 8:163
15. Abraham E, Singer M: Mechanisms of sepsis-induced organ dysfunction. Crit Care Med 2007; 35:2408-2416 (Pubitemid 47476242)