The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Oliver, Jason D ^a   Kaye, Sarah J ^a   Tuckwell, Danny ^a   Johns, Anna E ^b   Macdonald, Darel A ^b   Livermore, Joanne ^b   Warn, Peter A ^b   Birch, Mike ^a   Bromley, Michael J ^b  

^a F2G LTD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRANCHED CHAIN AMINO ACID; DIHYDROXYACID DEHYDRATASE ILV3A; DIHYDROXYACID DEHYDRATASE ILV3B; DIHYDROXYACID DEHYDRATASE ILVC; HYDROLYASE; ISOLEUCINE; RECOMBINANT ILV3A PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL GENE; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS MUTANT; GENE CLUSTER; GENE DELETION; GENE FUNCTION; GENE INACTIVATION; GENETIC ANALYSIS; ILV3A GENE; ILV3B GENE; IN VITRO STUDY; LUNG ASPERGILLOSIS; MALE; MOUSE; NEUTROPENIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYLOGENY; PROTEIN TARGETING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; BIOSYNTHETIC PATHWAYS; ENZYME ACTIVATION; FUNGAL PROTEINS; HYDRO-LYASES; MALE; MICE; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; VIRULENCE;

ASPERGILLUS FUMIGATUS; FUNGI; MURINAE; SACCHAROMYCES CEREVISIAE;

EID: 84866522315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043559     Document Type: Article

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