Moderate drinking? Alcohol consumption significantly decreases neurogenesis in the adult hippocampus

Neuroscience

Volumn 224, Issue , 2012, Pages 202-209

  Anderson, M L ^a   Nokia, M S ^b   Govindaraju, K P ^c   Shors, T J ^c  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

Adult neurogenesis; Alcohol; BrdU; Hippocampus; Sex differences; Trace eyeblink conditioning

Indexed keywords

ALCOHOL; BROXURIDINE; MALTODEXTRIN;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL LABELING; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; FEMALE; FLUID INTAKE; HIPPOCAMPUS; MALE; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; STATE DEPENDENT LEARNING; TASK PERFORMANCE;

ALCOHOL DRINKING; ANIMALS; CELL PROLIFERATION; FEMALE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MOTOR SKILLS; NEUROGENESIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84866519091     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.08.018     Document Type: Article

References (34)

1. Aberg E., Hofstetter C.P., Olson L., Brené S. Moderate ethanol consumption increases hippocampal cell proliferation and neurogenesis in the adult mouse. Int J Neuropsychopharmacol 2005, 8:557-567.
2. Anderson M.L., Sisti H.M., Curlik D.M., Shors T.J. Associative learning increases adult neurogenesis during a critical period. Eur J Neurosci 2011, 33:175-181.
3. Au Yeung S.L., Jiang C.Q., Cheng K.K., Liu B., Zhang W.S., Lam T.H., Leung G.M., Schooling C.M. Evaluation of moderate alcohol use and cognitive function among men using a mendelian randomization design in the guangzhou biobank cohort study. Am J Epidemiol 2012, Ahead of print.
4. Brummelte S., Galea L.A. Chronic high corticosterone reduces neurogenesis in the dentate gyrus of adult male and female rats. Neuroscience 2010, 168:680-690.
5. Cameron H.A., Woolley C.S., McEwen B.S., Gould E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience 1993, 56:337-344.
6. Curlik D.M., Shors T.J. Learning increases the survival of newborn neurons provided that learning is difficult to achieve and successful. J Cogn Neurosci 2011, 23:2159-2170.
7. Curlik II DM, Shors TJ (in press) Do mental and physical (MAP) training enhancecognition through the process of neurogenesis in the hippocampus? Neuropharmacology, in press.
8. Dalla C., Bangasser D.A., Edgecomb C., Shors T.J. Neurogenesis and learning: Acquisition and asymptotic performance predict how many new cells survive in the hippocampus. Neurobiol Learn Mem 2007, 88:143-148.
9. Dalla C., Papachristos E.B., Whetstone A.S., Shors T.J. Female rats learn trace memories better than male rats and consequently retain a greater proportion of new neurons in their hippocampi. Proc Natl Acad Sci USA 2009, 106:2927-2932.
10. Dufouil C., Ducimetière P., Alpérovitch A. Sex differences in the association between alcohol consumption and cognitive performance. EVA Study Group. Epidemiology of vascular aging. Am J Epidemiol 1997, 146:405-412.
11. Edelstein S.L., Kritz-Silverstein D., Barrett-Connor E. Prospective association of smoking and alcohol use with cognitive function in an elderly cohort. J Womens Health 1998, 7:1271-1281.
12. Espeland M.A., Gu L., Masaki K.H., Langer R.D., Coker L.H., Stefanick M.L., Ockene J., Rapp S.R. Association between reported alcohol intake and cognition: results from the Womens Health Initiative Memory Study. Am J Epidemiol 2005, 161:228-238.
13. Glenn M.J., Gibson E.M., Kirby E.D., Mellott T.J., Blusztajn J.K., Williams C.L. Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats. Eur J Neurosci 2007, 25:2473-2482.
14. Gould E., Beylin A., Tanapat P., Reeves A., Shors T.J. Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 1999, 2:260-265.
15. He J., Nixon K., Shetty A.K., Crews F.T. Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons. Eur J Neurosci 2005, 21:2711-2720.
16. He J., Overstreet D.H., Crews F.T. Abstinence from moderate alcohol self-administration alters progenitor cell proliferation and differentiation in multiple brain regions of male and female P rats. Alcohol Clin Exp Res 2009, 33:129-138.
17. Hodes G.E., Yang L., Van Kooy J., Santollo J., Shors T.J. Prozac during puberty: distinctive effects on neurogenesis as a function of age and sex. Neuroscience 2009, 163:609-617.
18. Leuner B., Glasper E.R., Gould E. Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones. PloS One 2010, 5:e11597.
19. Lukoyanov N.V., Brandão F., Cadete-Leite A., Madeira M.D., Paula-Barbosa M.M. Synaptic reorganization in the hippocampal formation of alcohol-fed rats may compensate for functional deficits related to neuronal loss. Alcohol 2000, 20:139-148.
20. Mezey E., Sharma S., Rennie L., Potter J.J. Sex differences in gastric alcohol dehydrogenase activity in Sprague-Dawley rats. Gastroenterology 1992, 103:1804-1810.
21. Ngandu T., Helkala E.L., Soininen H., Winblad B., Tuomilehto J., Nissinen A., Kivipelto M. Alcohol drinking and cognitive functions: findings from the Cardiovascular Risk Factors Aging and Dementia (CAIDE) Study. Demen Geriatr Cogn Disord 2007, 23:140-149.
22. Nixon K., Crews F.T. Binge ethanol exposure decreases neurogenesis in adult rat hippocampus. J Neurochem 2002, 83:1087-1093.
23. Nokia MS, Anderson ML, Shors TJ (in press) Chemotherapy disrupts learning, adult neurogenesis and theta activity in the hippocampus. European Journal of Neuroscience, in press.
24. Obernier J.A., Bouldin T.W., Crews F.T. Binge ethanol exposure in adult rats causes necrotic cell death. Alcoh Clin Exp Res 2002, 26:547-557.
25. Ronksley P.E., Brien S.E., Turner B.J., Mukamal K.J., Ghali W.A. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. BMJ 2011, 342:d671.
26. Shors T.J., Anderson M.L., Curlik D.M.n., Nokia MS. Use it or lose it: how neurogenesis keeps the brain fit for learning. Behav Brain Res 2012, 227:450-458.
27. Shors T.J., Miesegaes G., Beylin A.V., Zhao M., Rydel T., Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 2001, 410:372-376.
28. Shors T.J., Townsend D.A., Zhao M., Kozorovitskiy Y., Gould E. Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus 2002, 12:578-584.
29. Stampfer M.J., Kang J.H., Chen J., Cherry R., Grodstein F. Effects of moderate alcohol consumption on cognitive function in women. New Engl J Med 2005, 352:245-253.
30. van Praag H., Kempermann G., Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 1999, 2:266-270.
31. Verbaten M.N. Chronic effects of low to moderate alcohol consumption on structural and functional properties of the brain: beneficial or not?. Hum Psychopharacol 2009, 24:199-205.
32. Waddell J., Shors T.J. Neurogenesis, learning and associative strength. Eur J Neurosci 2008, 27:3020-3028.
33. Walker B.M., Walker J.L., Ehlers C.L. Dissociable effects of ethanol consumption during the light and dark phase in adolescent and adult Wistar rats. Alcohol 2008, 42:83-89.
34. West M.J., Slomianka L., Gundersen H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 1991, 231:482-497.