Neurogenesis and learning: Acquisition and asymptotic performance predict how many new cells survive in the hippocampus

Neurobiology of Learning and Memory

Volumn 88, Issue 1, 2007, Pages 143-148

  Dalla, Christina ^a   Bangasser, Debra A ^a   Edgecomb, Carol ^a   Shors, Tracey J ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Associative learning; BrdU; Dentate gyrus; Hippocampus; Neurogenesis; Time; Trace conditioning

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL SURVIVAL; CONDITIONED REFLEX; CONTROLLED STUDY; HIPPOCAMPUS; HUMAN; LABELING INDEX; LEARNING; MALE; MENTAL PERFORMANCE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; RAT; STIMULUS RESPONSE; TASK PERFORMANCE; TRAINING;

ANIMALS; ASSOCIATION LEARNING; CELL DIFFERENTIATION; CELL SURVIVAL; CONDITIONING, CLASSICAL; HIPPOCAMPUS; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 34249313322     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nlm.2007.02.003     Document Type: Article

References (28)

1. Bangasser D.A., Waxler D.E., Santollo J., and Shors T.J. Trace conditioning and the hippocampus: The importance of contiguity. Journal of Neuroscience 26 (2006) 8702-8706
2. Berger T.W., Rinaldi P.C., Weisz D.J., and Thompson R.F. Single-unit analysis of different hippocampal cell types during classical conditioning of rabbit nictitating membrane response. Journal of Neurophysiology 50 (1983) 1197-1219
3. Beylin A.V., Gandhi C.C., Wood G.E., Talk A.C., Matzel L.D., and Shors T.J. The role of the hippocampus in trace conditioning: Temporal discontinuity or task difficulty?. Neurobiology of Learning and Memory 76 (2001) 447-461
4. Cameron H.A., Woolley C.S., McEwen B.S., and Gould E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience 56 (1993) 337-344
5. Christie B.R., and Cameron H.A. Neurogenesis in the adult hippocampus. Hippocampus 16 (2006) 199-1207
6. Dayer A.G., Ford A.A., Cleaver K.M., Yassaee M., and Cameron H.A. Short-term and long-term survival of new neurons in the rat dentate gyrus. Journal of Comparative Neurology 460 (2003) 563-572
7. Drapeau E., Mayo W., Aurousseau C., Le Moal M., Piazza P.V., and Abrous D.N. Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America 100 (2003) 14385-14390
8. Gilmartin M.R., and McEchron M.D. Single neurons in the dentate gyrus and CA1 of the hippocampus exhibit inverse patterns of encoding during trace fear conditioning. Behavioral Neuroscience 119 (2005) 164-179
9. Gould E., Beylin A., Tanapat P., Reeves A., and Shors T.J. Learning enhances adult neurogenesis in the hippocampal formation. Nature Neuroscience 2 (1999) 260-265
10. Gould E., Tanapat P., Hastings N.B., and Shors T.J. Neurogenesis in adulthood: A possible role in learning. Trends in Cognitive Sciences 3 (1999) 186-192
11. Hairston I.S., Little M.T., Scanlon M.D., Barakat M.T., Palmer T.D., Sapolsky R.M., et al. Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning. Journal of Neurophysiology 94 (2005) 4224-4233
12. Kempermann G., and Gage F.H. Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. European Journal of Neuroscience 16 (2002) 129-136
13. Leuner B., Gould E., and Shors T.J. Is there a link between adult neurogenesis and learning?. Hippocampus 16 (2006) 216-224
14. Leuner B., Mendolia-Loffredo S., Kozorovitskiy Y., Samburg D., Gould E., and Shors T.J. Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory. Journal of Neuroscience 24 (2004) 7477-7481
15. Leuner B., Waddell J., Gould E., and Shors T.J. Temporal discontiguity is neither necessary nor sufficient for learning-induced effects on adult neurogenesis. Journal of Neuroscience 26 (2006) 13437-13442
16. Lledo P.M., Alonso M., and Grubb M.S. Adult neurogenesis and functional plasticity in neuronal circuits. Nature Reviews Neuroscience 7 (2006) 179-193
17. Madsen T.M., Kristjansen P.E., Bolwig T.G., and Wortwein G. Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat. Neuroscience 119 (2003) 635-642
18. Markakis E.A., and Gage F.H. Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles. Journal of Comparative Neurology 406 (1999) 449-460
19. McDonald H.Y., and Wojtowicz J.M. Dynamics of neurogenesis in the dentate gyrus of adult rats. Neuroscience Letters 385 (2005) 70-75
20. Moyer Jr. J.R., Thompson L.T., and Disterhoft J.F. Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. Journal of Neuroscience 16 (1996) 5536-5546
21. Ramirez-Amaya V., Marrone D.F., Gage F.H., Worley P.F., and Barnes C.A. Integration of new neurons into functional neural networks. Journal of Neuroscience 26 (2006) 12237-12241
22. Saxe M.D., Battaglia F., Wang J.W., Malleret G., David D.J., Monckton J.E., et al. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America 103 (2006) 17501-17506
23. Shors T.J. Memory traces of trace memories: Neurogenesis, synaptogenesis and awareness. Trends in Neurosciences 27 (2004) 250-256
24. Shors T.J., Miesegaes G., Beylin A., Zhao M., Rydel T., and Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410 (2001) 372-376
25. Solomon P.R., Vander Schaaf E.R., Thompson R.F., and Weisz D.J. Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response. Behavioral Neuroscience 100 (1986) 729-744
26. van Praag H., Schinder A.F., Christie B.R., Toni N., Palmer T.D., and Gage F.H. Functional neurogenesis in the adult hippocampus. Nature 415 (2002) 1030-1034
27. West M.J., Slomianka L., and Gundersen H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. The Anatomical Record 231 (1991) 482-497
28. Winocur G., Wojtowicz J.M., Sekeres M., Snyder J.S., and Wang S. Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus 16 (2006) 296-304