Topical delivery of clobetasol propionate loaded microemulsion based gel for effective treatment of vitiligo: Ex vivo permeation and skin irritation studies

Colloids and Surfaces B: Biointerfaces

Volumn 102, Issue , 2013, Pages 86-94

  Patel, Hetal ^a   Barot, Bhavesh S ^a   Parejiya, Punit B ^a   Shelat, Pragna K ^a   Shukla, Arunkumar ^a  

^a K B INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Clobetasol propionate; D Optimal design; Microemulsion; Permeation; Skin irritation

Indexed keywords

CARBOPOL; CLOBETASOL PROPIONATE; CO-SURFACTANTS; CUMULATIVE AMOUNT; D-OPTIMAL; D-OPTIMAL DESIGNS; EX-VIVO; GLOBULE SIZE; PERMEATION ENHANCEMENT; SCANNING ELECTRON MICROGRAPHS; SKIN IRRITATION; SKIN LAYER; SKIN STRUCTURE; TOPICAL DELIVERY;

DRUG DELIVERY; OPTIMIZATION; PERMEATION; SCANNING ELECTRON MICROSCOPY; SKIN; SOLUBILITY; TRANSMISSION ELECTRON MICROSCOPY; VOLATILE FATTY ACIDS;

MICROEMULSIONS;

CARBOMER; CLOBETASOL PROPIONATE; COSURFACTANT; OIL; SURFACTANT; WATER;

ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG RETENTION; DRUG SOLUBILITY; DRUG STRUCTURE; EX VIVO STUDY; EXPERIMENTAL DESIGN; GEL; GLOBULE SIZE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; MALE; MICROEMULSION; MICROPHOTOGRAPHY; MOLECULAR INTERACTION; NONHUMAN; PHYSICAL PARAMETERS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; SKIN IRRITATION; SKIN STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY; VISCOSITY; VITILIGO;

ANIMALS; CLOBETASOL; GELS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; RABBITS; SKIN; SKIN ABSORPTION; SURFACE-ACTIVE AGENTS; VITILIGO;

EID: 84866510857     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.08.011     Document Type: Article

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