Optimization of self-microemulsifying drug delivery systems (SMEDDS) using a D-optimal design and the desirability function

Drug Development and Industrial Pharmacy

Volumn 32, Issue 9, 2006, Pages 1025-1032

  Holm, R ^a   Jensen, I H M ^a   Sonnergaard, J ^b  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

D optimal design; Emulsion; Optimization; Self microemulsifying drug delivery systems

Indexed keywords

CARBOXYMETHYLCELLULOSE; CREMOPHOR; GELATIN; ISOBENZOFURAN DERIVATIVE; LU 28 179; MACROGOL 200; MEDIUM CHAIN TRIACYLGLYCEROL; POLYSORBATE 80; SIRAMESINE; SPIRO COMPOUND; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG SOLUBILITY; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL ANALYSIS; MICROEMULSION; PARTICLE SIZE;

CAPSULES; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG INCOMPATIBILITY; EMULSIONS; GELATIN; INDOLES; MODELS, CHEMICAL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SOLUBILITY; SPIRO COMPOUNDS; SURFACE-ACTIVE AGENTS; TRIGLYCERIDES;

EID: 33749454734     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040600559024     Document Type: Article

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