메뉴 건너뛰기




Volumn 31, Issue 9, 2012, Pages 945-954

Therapeutic effects of ivabradine on hemodynamic parameters and cardiotoxicity induced by doxorubicin treatment in rat

Author keywords

Cardiotoxicity; Doxorubucin; Hemodynamic Parameters; Ivabradine

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BIOCHEMICAL MARKER; CASPASE 3; CORALAN; CREATINE KINASE MB; DOXO TEVA; DOXORUBICIN; IVABRADINE; LACTATE DEHYDROGENASE; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 84866501531     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327112438288     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 33646123097 scopus 로고    scopus 로고
    • Beneficial role of aminoguanidine on acute cardiomyopathy related to doxorubicin-treatment
    • Cigremis Y, Parlakpinar H, Polat A, Colak C, Ozturk F, Sahna E, et al. Beneficial role of aminoguanidine on acute cardiomyopathy related to doxorubicin-treatment. Mol Cell Biochem. 2006 ; 285: 149-154
    • (2006) Mol Cell Biochem , vol.285 , pp. 149-154
    • Cigremis, Y.1    Parlakpinar, H.2    Polat, A.3    Colak, C.4    Ozturk, F.5    Sahna, E.6
  • 2
    • 0034781629 scopus 로고    scopus 로고
    • Doxorubicin, to treat cancers or to cause cardiac injury that is the question
    • Kitakaze M. Doxorubicin, to treat cancers or to cause cardiac injury that is the question. Cardiovasc Drugs Ther. 2001 ; 15: 199-200
    • (2001) Cardiovasc Drugs Ther , vol.15 , pp. 199-200
    • Kitakaze, M.1
  • 3
    • 0347722762 scopus 로고    scopus 로고
    • Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats
    • Fadillioglu E, Erdogan H, Sogut S, Kuku I. Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats. J Appl Toxicol. 2003 ; 23: 71-74
    • (2003) J Appl Toxicol , vol.23 , pp. 71-74
    • Fadillioglu, E.1    Erdogan, H.2    Sogut, S.3    Kuku, I.4
  • 4
    • 0036010747 scopus 로고    scopus 로고
    • Early changes in myocardial antioxidant enzymes in rats treated with adriamycin
    • Li T, Danelisen I, Singal PK. Early changes in myocardial antioxidant enzymes in rats treated with adriamycin. Mol Cell Biochem. 2002 ; 232: 19-26
    • (2002) Mol Cell Biochem , vol.232 , pp. 19-26
    • Li, T.1    Danelisen, I.2    Singal, P.K.3
  • 5
    • 44949192915 scopus 로고    scopus 로고
    • Central endothelin: Effects on vasopressin and the arterial baroreflex in doxorubicin heart failure rats
    • Rossi NF, Maliszewska-Scislo M, Chen H. Central endothelin: effects on vasopressin and the arterial baroreflex in doxorubicin heart failure rats. Can J Physiol Pharmacol. 2008 ; 86: 343-352
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 343-352
    • Rossi, N.F.1    Maliszewska-Scislo, M.2    Chen, H.3
  • 6
    • 43249091146 scopus 로고    scopus 로고
    • Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice
    • Custodis F, Baumhäkel M, Schlimmer N, List F, Gensch C, Böhm M, et al. Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2008 ; 117: 2377-2387
    • (2008) Circulation , vol.117 , pp. 2377-2387
    • Custodis, F.1    Baumhäkel, M.2    Schlimmer, N.3    List, F.4    Gensch, C.5    Böhm, M.6
  • 7
    • 1642416433 scopus 로고    scopus 로고
    • Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart disease
    • Sajadieh A, Nielsen OW, Rasmussen V, Hein HO, Abedini S, Hansen JF. Increased heart rate and reduced heart-rate variability are associated with subclinical inflammation in middle-aged and elderly subjects with no apparent heart disease. Eur Heart J. 2004 ; 25: 363-370
    • (2004) Eur Heart J , vol.25 , pp. 363-370
    • Sajadieh, A.1    Nielsen, O.W.2    Rasmussen, V.3    Hein, H.O.4    Abedini, S.5    Hansen, J.F.6
  • 8
    • 0035949564 scopus 로고    scopus 로고
    • Left ventricular muscle mass and elevated heart rate are associated with coronary plaque disruption
    • Heidland UE, Strauer BE. Left ventricular muscle mass and elevated heart rate are associated with coronary plaque disruption. Circulation. 2001 ; 104: 1477-1482
    • (2001) Circulation , vol.104 , pp. 1477-1482
    • Heidland, U.E.1    Strauer, B.E.2
  • 9
    • 22744450757 scopus 로고    scopus 로고
    • Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents
    • DiFrancesco D. Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents. Curr Med Res Opin. 2005 ; 21: 1115-1122
    • (2005) Curr Med Res Opin , vol.21 , pp. 1115-1122
    • Difrancesco, D.1
  • 10
    • 56749131836 scopus 로고    scopus 로고
    • Pleitropic action(s) of the bradycardic agent ivabradine: Cardiovascular protection beyond heart rate reduction
    • Heusch G. Pleitropic action(s) of the bradycardic agent ivabradine: cardiovascular protection beyond heart rate reduction. Br J Pharmacol. 2008 ; 155: 970-971
    • (2008) Br J Pharmacol , vol.155 , pp. 970-971
    • Heusch, G.1
  • 11
    • 0242333263 scopus 로고    scopus 로고
    • Melatonin protects against myocardial doxorubicin toxicity in rats: Role of physiological concentrations
    • Sahna E, Parlakpinar H, Ozer MK, Ozturk F, Ozugurlu F, Acet A. Melatonin protects against myocardial doxorubicin toxicity in rats: role of physiological concentrations. J Pineal Res. 2003 ; 35: 257-261
    • (2003) J Pineal Res , vol.35 , pp. 257-261
    • Sahna, E.1    Parlakpinar, H.2    Ozer, M.K.3    Ozturk, F.4    Ozugurlu, F.5    Acet, A.6
  • 12
    • 0018069570 scopus 로고
    • Determination of MDA precursor in tissue by TBA test
    • Uchiyama M, Mihara M. Determination of MDA precursor in tissue by TBA test. Anal Biochem. 1978 ; 36: 271-278
    • (1978) Anal Biochem , vol.36 , pp. 271-278
    • Uchiyama, M.1    Mihara, M.2
  • 13
    • 0023952554 scopus 로고
    • Simple method for clinical assay of superoxide dismutase
    • Sun USY, Oberley LW, Li YA. Simple method for clinical assay of superoxide dismutase. Clin Chem. 1988 ; 34: 497-500
    • (1988) Clin Chem , vol.34 , pp. 497-500
    • Usy, S.1    Oberley, L.W.2    Li, Y.A.3
  • 14
    • 0000024078 scopus 로고
    • Bergmeyer HU, ed. New York: Academic Press;
    • Aebi H Methods of Enzymatic Analysis. Bergmeyer HU, ed. New York: Academic Press ; 1974: 673-677.
    • (1974) Methods of Enzymatic Analysis , pp. 673-677
    • Aebi, H.1
  • 15
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967 ; 70: 158-170
    • (1967) J Lab Clin Med , vol.70 , pp. 158-170
    • Paglia, D.E.1    Valentine, W.N.2
  • 17
    • 0034931312 scopus 로고    scopus 로고
    • Protective effect of melatonin against adriamycin toxicity in the rat
    • Agapito MT, Antolin Y, del Brio MT. Protective effect of melatonin against adriamycin toxicity in the rat. J Pineal Res. 2001 ; 31: 23-30
    • (2001) J Pineal Res , vol.31 , pp. 23-30
    • Agapito, M.T.1    Antolin, Y.2    Del Brio, M.T.3
  • 18
    • 0035846881 scopus 로고    scopus 로고
    • Effects by doxorubicin on the myocardium are mediated by oxygen free radicals
    • Xu MF, Tang PL, Qian ZM. Effects by doxorubicin on the myocardium are mediated by oxygen free radicals. Life Sci. 2001 ; 68: 889-901
    • (2001) Life Sci , vol.68 , pp. 889-901
    • Xu, M.F.1    Tang, P.L.2    Qian, Z.M.3
  • 19
    • 0035831158 scopus 로고    scopus 로고
    • Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment-a review
    • De Beer EL, Bottone AE, Voest EE. Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment-a review. Eur J Pharmacol. 2001 ; 415: 1-11
    • (2001) Eur J Pharmacol , vol.415 , pp. 1-11
    • De Beer, E.L.1    Bottone, A.E.2    Voest, E.E.3
  • 21
    • 0022461967 scopus 로고
    • Vasoconstrictor role for vasopressin in experimental heart failure in the rabbit
    • Arnolda L, McGrath BP, Cocks M, Johnston CI. Vasoconstrictor role for vasopressin in experimental heart failure in the rabbit. J Clin Invest. 1986 ; 78: 674-679
    • (1986) J Clin Invest , vol.78 , pp. 674-679
    • Arnolda, L.1    McGrath, B.P.2    Cocks, M.3    Johnston, C.I.4
  • 22
    • 0035461784 scopus 로고    scopus 로고
    • Baroreflex sensitivity and oxidative stress in adriamycin-induced heart failure
    • Rabelo E, De Angelis K, Bock P. Baroreflex sensitivity and oxidative stress in adriamycin-induced heart failure. Hypertension. 2001 ; 38: 576-580
    • (2001) Hypertension , vol.38 , pp. 576-580
    • Rabelo, E.1    De Angelis, K.2    Bock, P.3
  • 23
    • 0031801988 scopus 로고    scopus 로고
    • Curcumin attenuation of acute adriamycin myocardial toxicity in rats
    • Venkatesan N. Curcumin attenuation of acute adriamycin myocardial toxicity in rats. Br J Pharmacol. 1998 ; 124: 425-427
    • (1998) Br J Pharmacol , vol.124 , pp. 425-427
    • Venkatesan, N.1
  • 24
    • 0025653237 scopus 로고
    • Heart rate proportional oxygen consumption for constant cardiac work in dog heart
    • Tanaka N, Nozawa T, Yasumura Y, Futaki S, Hiramori K, Suga H. Heart rate proportional oxygen consumption for constant cardiac work in dog heart. Jpn J Physiol. 1990 ; 40: 503-521
    • (1990) Jpn J Physiol , vol.40 , pp. 503-521
    • Tanaka, N.1    Nozawa, T.2    Yasumura, Y.3    Futaki, S.4    Hiramori, K.5    Suga, H.6
  • 26
    • 0025924392 scopus 로고
    • Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation
    • Ross J. Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation. Circulation. 1991 ; 83: 1076-1083
    • (1991) Circulation , vol.83 , pp. 1076-1083
    • Ross, J.1
  • 27
    • 52449095304 scopus 로고    scopus 로고
    • Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: Protection beyond heart rate reduction
    • Heusch G, Skyschally A, Gres P, van Caster P, Schilawa D, Schulz R. Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction. Eur Heart J. 2008 ; 29: 2265-2275
    • (2008) Eur Heart J , vol.29 , pp. 2265-2275
    • Heusch, G.1    Skyschally, A.2    Gres, P.3    Van Caster, P.4    Schilawa, D.5    Schulz, R.6
  • 28
    • 33646553077 scopus 로고    scopus 로고
    • Anti-ischemic effect of ivabradine
    • Ferrari R, Cargnoni A, Ceconi C. Anti-ischemic effect of ivabradine. Pharm Res. 2006 ; 53: 435-439
    • (2006) Pharm Res , vol.53 , pp. 435-439
    • Ferrari, R.1    Cargnoni, A.2    Ceconi, C.3
  • 29
    • 33646674434 scopus 로고    scopus 로고
    • Ivabradine-the first selective sinus node if channel inhibitor in the treatment of stable angina
    • Sulfi S, Timmis AD. Ivabradine-the first selective sinus node If channel inhibitor in the treatment of stable angina. Int J Clin Pract. 2006 ; 60: 222-228
    • (2006) Int J Clin Pract , vol.60 , pp. 222-228
    • Sulfi, S.1    Timmis, A.D.2
  • 30
    • 33747885881 scopus 로고    scopus 로고
    • Novel if current inhibitor ivabradine: Safety considerations
    • Sevelieva I, Camm AJ. Novel If current inhibitor ivabradine: safety considerations. Adv Cardiol. 2006 ; 43: 79-96
    • (2006) Adv Cardiol , vol.43 , pp. 79-96
    • Sevelieva, I.1    Camm, A.J.2
  • 31
    • 77953020434 scopus 로고    scopus 로고
    • Ivabradine: From molecular basis to clinical effectiveness
    • Riccioni G. Ivabradine: from molecular basis to clinical effectiveness. Adv Ther. 2010 ; 27: 160-167
    • (2010) Adv Ther , vol.27 , pp. 160-167
    • Riccioni, G.1
  • 32
    • 77952621797 scopus 로고    scopus 로고
    • Chronic heart rate reduction facilitates cardiomyocyte survival after myocardial infarction
    • Zhang RL, Christensen LP, Tomanek RJ. Chronic heart rate reduction facilitates cardiomyocyte survival after myocardial infarction. Anat Rec. 2010 ; 293: 839-848
    • (2010) Anat Rec , vol.293 , pp. 839-848
    • Zhang, R.L.1    Christensen, L.P.2    Tomanek, R.J.3
  • 35
    • 77956229711 scopus 로고    scopus 로고
    • Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice
    • Baumhakel M, Custodis F, Schlimmer N, Laufs U, Böhm M. Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice. Atherosclerozis. 2010 ; 212: 55-62
    • (2010) Atherosclerozis , vol.212 , pp. 55-62
    • Baumhakel, M.1    Custodis, F.2    Schlimmer, N.3    Laufs, U.4    Böhm, M.5
  • 36
    • 80155212934 scopus 로고    scopus 로고
    • Dose dependent protective effect of ivabradine against ischemia reperfusion induced renal injury in rats
    • Beytur A, Binbay M, Sarihan ME, Parlakpinar H, Polat A, Gunaydin MO, et al. Dose dependent protective effect of ivabradine against ischemia reperfusion induced renal injury in rats. Kidney Blood Press Res. 2011 ; 35 (2). 114-119
    • (2011) Kidney Blood Press Res , vol.35 , Issue.2 , pp. 114-119
    • Beytur, A.1    Binbay, M.2    Sarihan, M.E.3    Parlakpinar, H.4    Polat, A.5    Gunaydin, M.O.6
  • 37
    • 0029074824 scopus 로고
    • Effects of doxorubicin on cardiomyocytes with level of superoxide dismutase
    • Sarvazyan NA, Askari A, Huang WH. Effects of doxorubicin on cardiomyocytes with level of superoxide dismutase. Life Sci. 1995 ; 57: 1003-1010
    • (1995) Life Sci , vol.57 , pp. 1003-1010
    • Sarvazyan, N.A.1    Askari, A.2    Huang, W.H.3
  • 38
    • 33646783327 scopus 로고    scopus 로고
    • Vitamin e in the prevention of ischemic heart disease
    • Chattopadhyay A, Bandyopadhyay D. Vitamin E in the prevention of ischemic heart disease. Pharmacol Rep. 2006 ; 58: 179-187
    • (2006) Pharmacol Rep , vol.58 , pp. 179-187
    • Chattopadhyay, A.1    Bandyopadhyay, D.2
  • 39
    • 0029906872 scopus 로고    scopus 로고
    • Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro
    • Dorr RT, Lagel K, McLean S. Cardioprotection of rat heart myocytes with amifostine (Ethyol) and its free thiol, WR-1065, in vitro. Eur J Cancer. 1996 ; 32: 21-25
    • (1996) Eur J Cancer , vol.32 , pp. 21-25
    • Dorr, R.T.1    Lagel, K.2    McLean, S.3
  • 40
    • 0035912594 scopus 로고    scopus 로고
    • Doxorubicin-induced persistent oxidative stress to cardiac myocytes
    • Zhou S, Palmeira CM, Wallace KB. Doxorubicin-induced persistent oxidative stress to cardiac myocytes. Toxicol Lett. 2001 ; 21: 151-157
    • (2001) Toxicol Lett , vol.21 , pp. 151-157
    • Zhou, S.1    Palmeira, C.M.2    Wallace, K.B.3
  • 41
    • 49349104151 scopus 로고    scopus 로고
    • Protective effects of telmisartan against acute doxorubicin-induced cardiotoxicity in rats
    • Iqbal M, Dubey K, Anwer T, Ashish A, Pillai KK. Protective effects of telmisartan against acute doxorubicin-induced cardiotoxicity in rats. Pharmacol Rep. 2008 ; 60: 382-390
    • (2008) Pharmacol Rep , vol.60 , pp. 382-390
    • Iqbal, M.1    Dubey, K.2    Anwer, T.3    Ashish, A.4    Pillai, K.K.5
  • 43
    • 0034957066 scopus 로고    scopus 로고
    • The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats
    • Saad SY, Najjar TA, Al-Rikabi AC. The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats. Pharmacol Res. 2001 ; 43: 211-218
    • (2001) Pharmacol Res , vol.43 , pp. 211-218
    • Saad, S.Y.1    Najjar, T.A.2    Al-Rikabi, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.