Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

Oncology Reports

Volumn 28, Issue 4, 2012, Pages 1293-1300

  Wang, Xuan ^a   Zhang, Hongwei ^a   Zhang, Anling ^b,c   Han, Lei ^b,c   Wang, Kun ^d   Liu, Ran ^e   Yang, Shaohua ^e   Pu, Peiyu ^a,b,c   Shen, Changhong ^b   Kang, Chunsheng ^a,b,c   Yu, Chunjiang ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c Tian Jin Normal University   (China)

^d ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Brainstem glioma; microRNA; miR 106b; miR 20a; Pediatric tumor

Indexed keywords

MICRORNA; MICRORNA 106B; MICRORNA 20A; UNCLASSIFIED DRUG;

ADULT; ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM TUMOR; CANCER GROWTH; CHILDHOOD CANCER; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; JUVENILE ANIMAL; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; UPREGULATION; VALIDATION STUDY;

ADULT; AGE FACTORS; ANIMALS; BRAIN STEM NEOPLASMS; CHILD; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MALE; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, NUDE; REPRODUCIBILITY OF RESULTS; UP-REGULATION;

EID: 84866458098     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1927     Document Type: Article

References (34)

1. Hargrave D, Bartels U and Bouffet E: Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol 7: 241-248, 2006.
2. Laigle-Donadey F, Doz F and Delattre JY: Brainstem gliomas in children and adults. Curr Opin Oncol 20: 662-667, 2008.
3. Guillamo JS, Doz F and Delattre JY: Brain stem gliomas. Curr Opin Neurol 14: 711-715, 2001.
4. Mischel PS and Cloughesy TF: Targeted molecular therapy of GBM. Brain Pathol 13: 52-61, 2003.
5. Hwang JH, Smith CA, Salhia B and Rutka JT: The role of fascin in the migration and invasiveness of malignant glioma cells. Neoplasia 10: 149-159, 2008.
6. Guillamo JS, Monjour A, Taillandier L, Devaux B, Varlet P, Haie-Meder C, Defer GL, Maison P, Mazeron JJ, Cornu P and Delattre JY: Brainstem gliomas in adults: prognostic factors and classification. Brain 124: 2528-2539, 2001.
7. Mursch K, Halatsch ME, Markakis E and Behnke-Mursch J: Intrinsic brainstem tumours in adults: results of microneurosurgical treatment of 16 consecutive patients. Br J Neurosurg 19: 128-136, 2005.
8. Kesari S, Kim RS, Markos V, Drappatz J, Wen PY and Pruitt AA: Prognostic factors in adult brainstem gliomas: a multicenter, retrospective analysis of 101 cases. J Neurooncol 88: 175-183, 2008.
9. Epstein F and Wisoff JH: Surgical management of brain stem tumors of childhood and adolescence. Neurosurg Clin N Am 1: 111-121, 1990.
10. Liu Q, Liu R, Kashyap MV, Agarwal R, Shi X, Wang CC and Yang SH: Brainstem glioma progression in juvenile and adult rats. J Neurosurg 109: 849-855, 2008.
11. Gilbertson RJ, Hill DA, Hernan R, Kocak M, Geyer R, Olson J, Gajjar A, Rush L, Hamilton RL, Finkelstein SD and Pollack IF: ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma. Clin Cancer Res 9: 3620-3624, 2003.
12. Lee RC, Feinbaum RL and Ambros V: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854, 1993.
13. Karginov FV, Conaco C, Xuan Z, Schmidt BH, Parker JS, Mandel G and Hannon GJ: A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci USA 104: 19291-19296, 2007.
14. Cui Q, Yu Z, Purisima EO and Wang E: Principles of microRNA regulation of a human cellular signaling network. Mol Syst Biol 2: 46, 2006.
15. Wang X, Han L, Zhang A, Wang G, Jia Z, Yang Y, Yue X, Pu P, Shen C and Kang C: Adenovirus-mediated shRNAs for co-repression of miR-221 and miR-222 expression and function in glioblastoma cells. Oncol Rep 25: 97-105, 2011.
16. Bhatti I, Lee A, Lund J and Larvin M: Small RNA: a large contributor to carcinogenesis? J Gastrointest Surg 13: 1379-1388, 2009.
17. Song YJ, Tian XB, Zhang S, Zhang YX, Li X, Li D, Cheng Y, Zhang JN, Kang CS and Zhao W: Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b. Brain Res 1387: 134-140, 2011.
18. Selvapandian S, Rajshekhar V and Chandy MJ: Brainstem glioma: comparative study of clinico-radiological presentation, pathology and outcome in children and adults. Acta Neurochir 141: 721-727, 1999.
19. Jallo G: Brainstem gliomas. Childs Nerv Syst 22: 1-2, 2006.
20. Salmaggi A, Fariselli L, Milanesi I, Lamperti E, Silvani A, Bizzi A, Maccagnano E, Trevisan E, Laguzzi E, Ruda R, et al: Natural history and management of brainstem gliomas in adults. A retrospective Italian study. J Neurol 255: 171-177, 2008.
21. Yin LX, Li DZ, Zhang JT, Wu Z and Zhang LW: Comparison of clinical characteristics and surgical outcomes between adults and children with astrocytomas of brain stem. Zhong Guo Wei Qin Xi Shen Jing Wai Ke Za Zhi 15: 158-160, 2010.
22. Pang JC, Kwok WK, Chen Z and Ng HK: Oncogenic role of microRNAs in brain tumors. Acta Neuropathol 117: 599-611, 2009.
23. Bottoni A, Zatelli MC, Ferracin M, Tagliati F, Piccin D, Vignali C, Calin GA, Negrini M, Croce CM and Degli Uberti EC: Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J Cell Physiol 210: 370-377, 2007.
24. Gokhale A, Kunder R, Goel A, Sarin R, Moiyadi A, Shenoy A, Mamidipally C, Noronha S, Kannan S and Shirsat NV: Distinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway. J Cancer Res Ther 6: 521-529, 2010.
25. Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM and Farace MG: Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 334: 1351-1358, 2005.
26. Miwa T, Hirose Y, Sasaki H, Ikeda E, Yoshida K and Kawase T: Genetic characterization of adult infratentorial gliomas. J Neurooncol 91: 251-255, 2009.
27. Hashizume R, Ozawa T, Dinca EB, Banerjee A, Prados MD, James CD and Gupta N: A human brainstem glioma xenograft model enabled for bioluminescence imaging. J Neurooncol 96: 151-159, 2010.
28. Yaz G, Kabadere S, Oztopcu P, Durmaz R and Uyar R: Comparison of the antiproliferative properties of antiestrogenic drugs (nafoxidine and clomiphene) on glioma cells in vitro. Am J Clin Oncol 27: 384-388, 2004.
29. Petrocca F, Vecchione A and Croce CM: Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res 68: 8191-8194, 2008.
30. Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM, Kobayashi SV, Lim L, Burchard J, Jackson AL, et al: MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol 28: 2167-2174, 2008.
31. Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N and Sawada K: MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 113: 396-402, 2009.
32. Peck B, Schulze A, Oliveras-Ferraros C, Vellon L, Joven J and Vazquez-Martin A: A role for the cancer-associated miR-106b~25 cluster in neuronal stem cells. Aging (Albany NY) 3: 329-331, 2011.
33. Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stuhler K, Meyer HE and Reifenberger G: Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol 20: 539-550, 2010.
34. Zhou X, Ren Y, Moore L, Mei M, You Y, Xu P, Wang B, Wang G, Jia Z, Pu P, Zhang W and Kang C: Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest 90: 144-155, 2010.