Adrenomedullin is involved in the progression of colonic adenocarcinoma

Molecular Medicine Reports

Volumn 6, Issue 5, 2012, Pages 1030-1034

  Kim, Jee Youn ^a   Park, Won Do ^a   Sun, Lee ^a   Park, Jae Hoon ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Adrenomedullin; Cancer promotion; Colon cancer; Stomach cancer

Indexed keywords

ADRENOMEDULLIN;

ARTICLE; CANCER GROWTH; CANCER STAGING; CANCER SURVIVAL; COLON ADENOCARCINOMA; COLON CANCER; COLON MUCOSA; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION; STOMACH CANCER; STOMACH MUCOSA;

ADENOCARCINOMA; ADRENOMEDULLIN; COLONIC NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; NEOPLASM STAGING; STOMACH NEOPLASMS;

EID: 84866445334     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1045     Document Type: Article

References (24)

1. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H and Eto T: Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 192: 553-560, 1993. (Pubitemid 23227359)
2. Eipper BA, Stoffers DA and Mains RE: The biosynthesis of neuropeptides: peptide α-amidation (Review). Annu Rev Neurosci 15: 57-85, 1992.
3. Kamitani S, Asakawa M, Shimekake Y, Kuwasako K, Nakahara K and Sakata T: The RAMP2/CRLR complex is a functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells. FEBS Lett 448: 111-114, 1999. (Pubitemid 29151640)
4. Hinson JP, Kapas S and Smith DM: Adrenomedullin, a multifunctional regulatory peptide (Review). Endocr Rev 21: 138-167, 2000. (Pubitemid 32275593)
5. Li Z, Takeuchi S, Otani T and Maruo T: Implications of adrenomedullin expression in the invasion of squamous cell carcinoma of the uterine cervix. Int J Clin Oncol 6: 263-270, 2001. (Pubitemid 34137226)
6. Martínez A, Vos M, Guédez L, Kaur G, Chen Z, Garayoa M, Pío R, Moody T, Stetler-Stevenson WG, Kleinman HK and Cuttitta F: The effects of adrenomedullin overexpression in breast tumor cells. J Natl Cancer Inst 94: 1226-1237, 2002. (Pubitemid 34993873)
7. Zudaire E, Martínez A and Cuttitta F: Adrenomedullin and cancer (Review). Regul Pept 112: 175-183, 2003. (Pubitemid 36351615)
8. Hanahan D and Weinberg RA: The hallmarks of cancer (Review). Cell 100: 57-70, 2000. (Pubitemid 30046295)
9. Möller P, Koretz K, Leithäuser F, Brüderlein S, Henne C, Quentmeier A and Krammer PH: Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium. Int J Cancer 57: 371-377, 1994. (Pubitemid 24168612)
10. Rich JN, Borton AJ and Wang X: Transforming growth factor-b signaling in cancer (Review). Microsc Res Tech 52: 363-373, 2001. (Pubitemid 32167824)
11. Oehler MK, Norbury C, Hague S, Rees MC and Bicknell R: Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth. Oncogene 20: 2937-2945, 2001. (Pubitemid 33027761)
12. Ryu BK, Lee MG, Chi SG, Kim YW and Park JH: Increased expression of cFLIP(L) in colonic adenocarcinoma. J Pathol 194: 15-19, 2001.
13. Hinson JP, Thomson LM and Kapas S. Adrenomedullin and CGRP receptors mediate different effects in the rat adrenal cortex. Endocr Res 24: 725-728, 1998. (Pubitemid 29016468)
14. Satoh F, Takahashi K, Murakami O, Totsune K, Sone M, Ohneda M, Abe K, Miura Y, Hayashi Y and Sasano H: Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma. J Clin Endocrinol Metab 80: 1750-1752, 1995.
15. Martinez A, Miller MJ, Unsworth EJ, Siegfried JM and Cuttitta F: Expression of adrenomedullin in normal human lung and in pulmonary tumors. Endocrinology 136: 4099-4105, 1995.
16. Ouafik L, Sauze S, Boudouresque F, Chinot O, Delfino C, Fina F, Vuaroqueaux V, Dussert C, Palmari J, Dufour H, et al: Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo. Am J Pathol 160: 1279-1292, 2002. (Pubitemid 34411632)
17. Miller MJ, Martínez A, Unsworth EJ, Thiele CJ, Moody TW, Elsasser T and Cuttitta F: Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor. J Biol Chem 271: 23345-23351, 1996. (Pubitemid 26314779)
18. Nakayama M, Takahashi K, Murakami O, Shirato K and Shibahara S: Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells. Biochem Biophys Res Commun 243: 514-517, 1998. (Pubitemid 28414056)
19. Kitani M, Sakata J, Asada Y, Kitamura K and Eto T: Distribution and expression of adrenomedullin in human gastrointestinal tissue. Ann Clin Biochem 35: 643-648, 1998. (Pubitemid 28434575)
20. Marutsuka K, Nawa Y, Asada Y, Hara S, Kitamura K, Eto T and Sumiyoshi A: Adrenomedullin and proadrenomudullin N-terminal 20 peptide (PAMP) are present in human colonic epithelia and exert an antimicrobial effect. Exp Physiol 86: 543-545, 2001. (Pubitemid 32910341)
21. Garayoa M, Martínez A, Lee S, Pio R, An WG, Neckers L, Trepel J, Montuenga LM, Ryan H, Johnson R, et al: Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. Mol Endocrinol 14: 848-862, 2000. (Pubitemid 32260498)
22. Zhao Y, Hague S, Manek S, Zhang L, Bicknell R and Rees MC: PCR display identifies tamoxifen induction of the novel angiogenic factor adrenomedullin by an non estrogenic mechanism in the human endometrium. Oncogene 16: 409-415, 1998. (Pubitemid 28052295)
23. Kim W, Moon SO, Sung MJ, Kim SH, Lee S, Kim HJ, Koh GY and Park SK: Protective effect of adrenomedullin in mannitol-induced apoptosis. Apoptosis 7: 527-536, 2002. (Pubitemid 35334447)
24. Kamoi H, Kanazawa H, Hirata K, Kurihara N, Yano Y and Otani S: Adrenomedullin inhibits the secretion of cytokine-induced neurtophil chemoattractant, a member of the interleukin-8 family, from rat alveolar macrophages. Biochem Biophys Res Commun 211: 1031-1035, 1995.