메뉴 건너뛰기




Volumn 24, Issue 5, 2012, Pages 584-591

Personalized medicine in pediatric cardiology: Do little changes make a big difference?

Author keywords

Congenital heart disease; genomics; pediatric cardiology; personalized medicine; pharmacogenomics

Indexed keywords

ANTHRACYCLINE; BUCINDOLOL; CLOPIDOGREL; DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TACROLIMUS; WARFARIN;

EID: 84866434141     PISSN: 10408703     EISSN: 1531698X     Source Type: Journal    
DOI: 10.1097/MOP.0b013e328357a4ea     Document Type: Review
Times cited : (9)

References (32)
  • 1
    • 79953746638 scopus 로고    scopus 로고
    • Personalized medicine: The promised land-are we there yet?
    • Li C. Personalized medicine: the promised land-are we there yet? Clin Genet 2011; 79:403-412.
    • (2011) Clin Genet , vol.79 , pp. 403-412
    • Li, C.1
  • 2
    • 84858667843 scopus 로고    scopus 로고
    • Personalized medicine in the genomics era: Highlights from an international symposium on childhood heart disease
    • Farra N, Manickaraj AK, Ellis J, Mital S. Personalized medicine in the genomics era: highlights from an international symposium on childhood heart disease. Future Cardiol 2012; 8:157-160.
    • (2012) Future Cardiol , vol.8 , pp. 157-160
    • Farra, N.1    Manickaraj, A.K.2    Ellis, J.3    Mital, S.4
  • 3
    • 80053040020 scopus 로고    scopus 로고
    • Cardiovascular Pharmacoge-nomics
    • Roden DM, Johnson JA, Kimmel SE, et al. Cardiovascular Pharmacoge-nomics. Circ Res 2011; 109:807-820.
    • (2011) Circ Res , vol.109 , pp. 807-820
    • Roden, D.M.1    Johnson, J.A.2    Kimmel, S.E.3
  • 4
    • 77957601615 scopus 로고    scopus 로고
    • Genetic factors in nonsyndromic congenital heart malformations
    • Wessels MW, Willems PJ. Genetic factors in nonsyndromic congenital heart malformations. Clin Genet 2010; 78:103-123.
    • (2010) Clin Genet , vol.78 , pp. 103-123
    • Wessels, M.W.1    Willems, P.J.2
  • 5
    • 68149181705 scopus 로고    scopus 로고
    • De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot
    • Greenway SC, Pereira AC, Lin JC, etal. De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot. Nat Genet 2009; 41:931-935.
    • (2009) Nat Genet , vol.41 , pp. 931-935
    • Greenway, S.C.1    Pereira, A.C.2    Lin, J.C.3
  • 6
    • 77956291376 scopus 로고    scopus 로고
    • Common variation in ISL1 confers genetic susceptibility for human congenital heart disease
    • Stevens KN, Hakonarson H, Kim CE, et al. Common variation in ISL1 confers genetic susceptibility for human congenital heart disease. PLoS ONE 2010; 5:e10855.
    • (2010) PLoS ONE , vol.5
    • Stevens, K.N.1    Hakonarson, H.2    Kim, C.E.3
  • 7
    • 84858257118 scopus 로고    scopus 로고
    • Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls
    • Soemedi R, Topf A, Wilson IJ, et al. Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls. Hum Mol Genet 2012; 21:1513-1520.
    • (2012) Hum Mol Genet , vol.21 , pp. 1513-1520
    • Soemedi, R.1    Topf, A.2    Wilson, I.J.3
  • 8
    • 84864586852 scopus 로고    scopus 로고
    • Common variant in the PTPN11 gene contri-butes to the risk of tetralogy of Fallot
    • Goodship JA, Hall D, Topf A, et al. Common variant in the PTPN11 gene contri-butes to the risk of tetralogy of Fallot. Circ Cardiovasc Genet 2012; 5:287
    • (2012) Circ Cardiovasc Genet , vol.5 , pp. 287
    • Goodship, J.A.1    Hall, D.2    Topf, A.3
  • 9
    • 79952593835 scopus 로고    scopus 로고
    • Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects
    • McBride KL, Zender GA, Fitzgerald-Butt SM, et al. Association of common variants in ERBB4 with congenital left ventricular outflow tract obstruction defects. Birth Defects Res A Clin Mol Teratol 2011; 91:162-168.
    • (2011) Birth Defects Res A Clin Mol Teratol , vol.91 , pp. 162-168
    • McBride, K.L.1    Zender, G.A.2    Fitzgerald-Butt, S.M.3
  • 10
    • 84860741138 scopus 로고    scopus 로고
    • Sporadic autism exomes reveal a highly interconnected protein networkof denovo mutations
    • O'Roak BJ, Vives L, Girirajan S, et al. Sporadic autism exomes reveal a highly interconnected protein networkof denovo mutations. Nature 2012; 485:246
    • (2012) Nature , vol.485 , pp. 246
    • O'Roak, B.J.1    Vives, L.2    Girirajan, S.3
  • 11
    • 84860788246 scopus 로고    scopus 로고
    • Exome analysis of a family with pleiotropic congenital heart disease/clinical perspective
    • Arrington CB, Bleyl SB, Matsunami N, et al. Exome analysis of a family with pleiotropic congenital heart disease/clinical perspective. Circ Cardiovasc Genet 2012; 5:175-182.
    • (2012) Circ Cardiovasc Genet , vol.5 , pp. 175-182
    • Arrington, C.B.1    Bleyl, S.B.2    Matsunami, N.3
  • 13
    • 84866370851 scopus 로고    scopus 로고
    • Clinical utility of noninvasive fetal trisomy (NIFTY) test: Early experience
    • Epub ahead of print
    • Lau TK, Chan MK, Salome Lo PS, et al. Clinical utility of noninvasive fetal trisomy (NIFTY) test: early experience. J Matern Fetal Neonatal Med 2012. [Epub ahead of print]
    • (2012) J Matern Fetal Neonatal Med
    • Lau, T.K.1    Chan, M.K.2    Salome Lo, P.S.3
  • 14
    • 84859363202 scopus 로고    scopus 로고
    • Noninvasive prenatal diagnosis of common fetal chromosomal aneuploidies by maternal plasma DNA sequencing
    • Epub ahead of print
    • Lau TK, Chen F, Pan X, et al. Noninvasive prenatal diagnosis of common fetal chromosomal aneuploidies by maternal plasma DNA sequencing. J Matern Fetal Neonatal Med 2012. [Epub ahead of print]
    • (2012) J Matern Fetal Neonatal Med
    • Lau, T.K.1    Chen, F.2    Pan, X.3
  • 15
    • 65449139505 scopus 로고    scopus 로고
    • Importance of gene-environment interactions in the etiology of selected birth defects
    • Zhu H, Kartiko S, Finnell RH. Importance of gene-environment interactions in the etiology of selected birth defects. Clin Genet 2009; 75:409-423.
    • (2009) Clin Genet , vol.75 , pp. 409-423
    • Zhu, H.1    Kartiko, S.2    Finnell, R.H.3
  • 16
    • 75749152463 scopus 로고    scopus 로고
    • Variants of folate metabolism genes and the risk of conotruncal cardiac defects
    • Goldmuntz E, Woyciechowski S, Renstrom D, et al. Variants of folate metabolism genes and the risk of conotruncal cardiac defects. Circ Cardio-vasc Genet 2008; 1:126-132.
    • (2008) Circ Cardio-vasc Genet , vol.1 , pp. 126-132
    • Goldmuntz, E.1    Woyciechowski, S.2    Renstrom, D.3
  • 17
    • 80053959531 scopus 로고    scopus 로고
    • Evaluation of heterogeneity in the association between congenital heart defects and variants of folate metabolism genes: Conotruncal and left-sided cardiac defects
    • Long J, Lupo PJ, Goldmuntz E, Mitchell LE. Evaluation of heterogeneity in the association between congenital heart defects and variants of folate metabolism genes: conotruncal and left-sided cardiac defects. Birth Defects Res A Clin Mol Teratol 2011; 91:879-884.
    • (2011) Birth Defects Res A Clin Mol Teratol , vol.91 , pp. 879-884
    • Long, J.1    Lupo, P.J.2    Goldmuntz, E.3    Mitchell, L.E.4
  • 18
    • 77955172447 scopus 로고    scopus 로고
    • Enalapril in infants with single ventricle
    • Hsu DT, Zak V, Mahony L, et al. Enalapril in infants with single ventricle. Circulation 2010; 122:333-340.
    • (2010) Circulation , vol.122 , pp. 333-340
    • Hsu, D.T.1    Zak, V.2    Mahony, L.3
  • 19
    • 79958100222 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle/clinical perspective
    • Mital S, Chung WK, Colan SD, et al. Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle/clinical perspective. Circulation 2011; 123:2353-2362.
    • (2011) Circulation , vol.123 , pp. 2353-2362
    • Mital, S.1    Chung, W.K.2    Colan, S.D.3
  • 20
    • 84873983241 scopus 로고    scopus 로고
    • Hypoxia-inducible factor gene polymorphisms and right ventricular adaptation in children after tetralogy of fallot repair
    • Jeewa A, Mertens L, Manlhiot C, et al. Hypoxia-inducible factor gene polymorphisms and right ventricular adaptation in children after tetralogy of fallot repair. Circulation 2010; 122:A17289.
    • (2010) Circulation , vol.122
    • Jeewa, A.1    Mertens, L.2    Manlhiot, C.3
  • 21
    • 84863661584 scopus 로고    scopus 로고
    • Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease
    • Zhang H, Gong D-X, Zhang YJ, et al. Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. Eur Heart J 2012; 33:1606-1614.
    • (2012) Eur Heart J , vol.33 , pp. 1606-1614
    • Zhang, H.1    Gong, D.-X.2    Zhang, Y.J.3
  • 22
    • 82455175258 scopus 로고    scopus 로고
    • A genetic contribution to risk for postoperative junctional ectopic tachycardia in children undergoing surgery for congenital heart disease
    • Borgman KY, Smith AH, Owen JP, et al. A genetic contribution to risk for postoperative junctional ectopic tachycardia in children undergoing surgery for congenital heart disease. Heart Rhythm 2011; 8:1900-1904.
    • (2011) Heart Rhythm , vol.8 , pp. 1900-1904
    • Borgman, K.Y.1    Smith, A.H.2    Owen, J.P.3
  • 23
    • 65549112600 scopus 로고    scopus 로고
    • Recipient genotype is a predictor of allograft cytokine expression and outcomes after pediatric cardiac transplantation
    • Auerbach SR, Manlhiot C, Reddy S, et al. Recipient genotype is a predictor of allograft cytokine expression and outcomes after pediatric cardiac transplantation. J Am Coll Cardiol 2009; 53:1909-1917.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1909-1917
    • Auerbach, S.R.1    Manlhiot, C.2    Reddy, S.3
  • 24
    • 47049104607 scopus 로고    scopus 로고
    • Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: A multi-institutional study
    • 10.1097/TP.0b013e3181722edc
    • Girnita DM, Brooks MM, Webber SA, et al. Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study. Transplantation 2008; 85:1632-1639; 10.1097/TP.0b013e3181722edc.
    • (2008) Transplantation , vol.85 , pp. 1632-1639
    • Girnita, D.M.1    Brooks, M.M.2    Webber, S.A.3
  • 25
    • 79959280748 scopus 로고    scopus 로고
    • The 14-bp deletion in the HLA-G gene indicates a low risk for acute cellular rejection in heart transplant recipients
    • Twito T, Joseph J, Mociornita A, et al. The 14-bp deletion in the HLA-G gene indicates a low risk for acute cellular rejection in heart transplant recipients. J Heart Lung Transplant 2011; 30:778-782.
    • (2011) J Heart Lung Transplant , vol.30 , pp. 778-782
    • Twito, T.1    Joseph, J.2    Mociornita, A.3
  • 26
    • 79955037043 scopus 로고    scopus 로고
    • Universal noninvasive detection of solid organ transplant rejection
    • Snyder TM, Khush KK, Valantine HA, Quake SR. Universal noninvasive detection of solid organ transplant rejection. Proc Natl Acad Sci 2011; 108:6229-6234.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 6229-6234
    • Snyder, T.M.1    Khush, K.K.2    Valantine, H.A.3    Quake, S.R.4
  • 27
    • 80052769827 scopus 로고    scopus 로고
    • Pharmacogenomics of cardiovascular drugs and adverse effects in pediatrics
    • Visscher H, Amstutz U, Sistonen J, et al. Pharmacogenomics of cardiovascular drugs and adverse effects in pediatrics. J Cardiovasc Pharmacol 2011; 58:228-239.
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 228-239
    • Visscher, H.1    Amstutz, U.2    Sistonen, J.3
  • 28
    • 80655147017 scopus 로고    scopus 로고
    • Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients
    • Gijsen V, Mital S, van Schaik RH, et al. Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. J Heart Lung Transplant 2011; 30:1352-1359.
    • (2011) J Heart Lung Transplant , vol.30 , pp. 1352-1359
    • Gijsen, V.1    Mital, S.2    Van Schaik, R.H.3
  • 29
    • 84863001655 scopus 로고    scopus 로고
    • Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children
    • Visscher H, Ross CJD, Rassekh SR, et al. Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children. J Clin Oncol 2012; 30:1422-1428.
    • (2012) J Clin Oncol , vol.30 , pp. 1422-1428
    • Visscher, H.1    Ross, C.J.D.2    Rassekh, S.R.3
  • 30
    • 79960401558 scopus 로고    scopus 로고
    • Personalizing medicine for the child with heart disease: A path forward
    • 10.1097/FJC.0b013e3182239ed7
    • Mital S. Personalizing medicine for the child with heart disease: a path forward. J Cardiovasc Pharmacol 2011; 58:1-3; 10.1097/FJC.0b013e3182239ed7.
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 1-3
    • Mital, S.1
  • 31
    • 80052455709 scopus 로고    scopus 로고
    • Genetic counseling in the adult with congenital heart disease: What is the role?
    • Burchill L, Greenway S, Silversides C, Mital S. Genetic counseling in the adult with congenital heart disease: what is the role? Curr Cardiol Rep 2011; 13:347-355.
    • (2011) Curr Cardiol Rep , vol.13 , pp. 347-355
    • Burchill, L.1    Greenway, S.2    Silversides, C.3    Mital, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.