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Volumn 72, Issue 18, 2012, Pages 4616-4621

Role of the human high-affinity copper transporter in copper homeostasis regulation and cisplatin sensitivity in cancer chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CARRIER PROTEIN; CISPLATIN; COPPER; COPPER TRANSPORTER 1; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; PLATINUM COMPLEX; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; THIOMOLYBDIC ACID; TRIENTINE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84866426370     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0888     Document Type: Review
Times cited : (92)

References (31)
  • 1
    • 0037195066 scopus 로고    scopus 로고
    • Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
    • Ishida S, Lee J, Thiele DJ, Herskowitz I. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A 2002;99:14298-302.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14298-14302
    • Ishida, S.1    Lee, J.2    Thiele, D.J.3    Herskowitz, I.4
  • 3
    • 18244379333 scopus 로고    scopus 로고
    • Cellular processing of platinum anticancer drugs
    • Wang D, Lippard SJ. Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 2005;4:307-20.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 307-320
    • Wang, D.1    Lippard, S.J.2
  • 4
    • 70349336140 scopus 로고    scopus 로고
    • Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin
    • Liang ZD, Stockton D, Savaraj N, Tien Kuo M. Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin. Mol Pharmacol 2009;76:843-53.
    • (2009) Mol Pharmacol , vol.76 , pp. 843-853
    • Liang, Z.D.1    Stockton, D.2    Savaraj, N.3    Tien Kuo, M.4
  • 6
    • 2942573029 scopus 로고    scopus 로고
    • Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells
    • Beretta GL, Gatti L, Tinelli S, Corna E, Colangelo D, Zunino F, et al. Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells. Biochem Pharmacol 2004;68:283-91.
    • (2004) Biochem Pharmacol , vol.68 , pp. 283-291
    • Beretta, G.L.1    Gatti, L.2    Tinelli, S.3    Corna, E.4    Colangelo, D.5    Zunino, F.6
  • 7
    • 77952341427 scopus 로고    scopus 로고
    • Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs
    • Howell SB, Safaei R, Larson CA, Sailor MJ. Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs. Mol Pharmacol 2010;77:887-94.
    • (2010) Mol Pharmacol , vol.77 , pp. 887-894
    • Howell, S.B.1    Safaei, R.2    Larson, C.A.3    Sailor, M.J.4
  • 9
    • 33748922789 scopus 로고    scopus 로고
    • Contribution of the major copper influx transporter CTR1 to the cellular accumulation of cisplatin, carboplatin, and oxaliplatin
    • Holzer AK, Manorek GH, Howell SB. Contribution of the major copper influx transporter CTR1 to the cellular accumulation of cisplatin, carboplatin, and oxaliplatin. Mol Pharmacol 2006;70:1390-4.
    • (2006) Mol Pharmacol , vol.70 , pp. 1390-1394
    • Holzer, A.K.1    Manorek, G.H.2    Howell, S.B.3
  • 10
    • 77953270903 scopus 로고    scopus 로고
    • Enhancing tumor-specific uptake of the anticancer drug cisplatin with a copper chelator
    • Ishida S, McCormick F, Smith-McCune K, Hanahan D. Enhancing tumor-specific uptake of the anticancer drug cisplatin with a copper chelator. Cancer Cell 2010;17:574-83.
    • (2010) Cancer Cell , vol.17 , pp. 574-583
    • Ishida, S.1    McCormick, F.2    Smith-McCune, K.3    Hanahan, D.4
  • 11
    • 52649085237 scopus 로고    scopus 로고
    • Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
    • Tothill RW, Tinker AV, George J, Brown R, Fox SB, Lade S, et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin Cancer Res 2008;14:5198-208.
    • (2008) Clin Cancer Res , vol.14 , pp. 5198-5208
    • Tothill, R.W.1    Tinker, A.V.2    George, J.3    Brown, R.4    Fox, S.B.5    Lade, S.6
  • 12
    • 84866360659 scopus 로고    scopus 로고
    • Mechanistic basis for overcoming platinum resistance using copper chelating agents
    • Aug 21 Epub ahead of print
    • Liang ZD, Long Y, Tsai WB, Fu S, Kurzrock R, Gagea-Iurascu M, et al. Mechanistic basis for overcoming platinum resistance using copper chelating agents. Mol Cancer Ther 2012 Aug 21 [Epub ahead of print].
    • (2012) Mol Cancer Ther
    • Liang, Z.D.1    Long, Y.2    Tsai, W.B.3    Fu, S.4    Kurzrock, R.5    Gagea-Iurascu, M.6
  • 13
    • 84855418559 scopus 로고    scopus 로고
    • Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy
    • Chen HH, Yan JJ, Chen WC, Kuo MT, Lai YH, Lai WW, et al. Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy. Lung Cancer 2012;75:228-34.
    • (2012) Lung Cancer , vol.75 , pp. 228-234
    • Chen, H.H.1    Yan, J.J.2    Chen, W.C.3    Kuo, M.T.4    Lai, Y.H.5    Lai, W.W.6
  • 14
    • 50449087893 scopus 로고    scopus 로고
    • Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1
    • Chen HH, Song IS, Hossain A, Choi M-K, Yamane Y, Liang ZD, et al. Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1. Mol Pharmacol 2008;74:697-704.
    • (2008) Mol Pharmacol , vol.74 , pp. 697-704
    • Chen, H.H.1    Song, I.S.2    Hossain, A.3    Choi, M.-K.4    Yamane, Y.5    Liang, Z.D.6
  • 15
    • 84863116664 scopus 로고    scopus 로고
    • Specifi city protein 1 (sp1) oscillation is involved in copper homeostasis maintenance by regulating human high-affinity copper transporter 1 expression
    • Liang ZD, Tsai WB, Lee MY, Savaraj N, Kuo MT. Specifi city protein 1 (sp1) oscillation is involved in copper homeostasis maintenance by regulating human high-affinity copper transporter 1 expression. Mol Pharmacol 2012;81:455-64.
    • (2012) Mol Pharmacol , vol.81 , pp. 455-464
    • Liang, Z.D.1    Tsai, W.B.2    Lee, M.Y.3    Savaraj, N.4    Kuo, M.T.5
  • 16
    • 50449111002 scopus 로고    scopus 로고
    • Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells
    • Song IS, Chen HH, Aiba I, Hossain A, Liang ZD, Klomp LW, et al. Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells. Mol Pharmacol 2008;74:705-13.
    • (2008) Mol Pharmacol , vol.74 , pp. 705-713
    • Song, I.S.1    Chen, H.H.2    Aiba, I.3    Hossain, A.4    Liang, Z.D.5    Klomp, L.W.6
  • 17
    • 84862570268 scopus 로고    scopus 로고
    • Overcoming platinum resistance through the use of a copper-lowering agent
    • Fu S, Naing A, Fu C, Kuo MT, Kurzrock R. Overcoming platinum resistance through the use of a copper-lowering agent. Mol Cancer Ther 2012;11:1221-5.
    • (2012) Mol Cancer Ther , vol.11 , pp. 1221-1225
    • Fu, S.1    Naing, A.2    Fu, C.3    Kuo, M.T.4    Kurzrock, R.5
  • 18
    • 77957890686 scopus 로고    scopus 로고
    • Role of glutathione in the regulation of Cisplatin resistance in cancer chemotherapy
    • Chen HH, Kuo MT. Role of glutathione in the regulation of Cisplatin resistance in cancer chemotherapy. Met Based Drugs 2010;2010:1-7.
    • (2010) Met Based Drugs , vol.2010 , pp. 1-7
    • Chen, H.H.1    Kuo, M.T.2
  • 19
    • 80755187849 scopus 로고    scopus 로고
    • Copper: An essential metal in biology
    • Festa RA, Thiele DJ. Copper: an essential metal in biology. Curr Biol 2011;21:R877-83.
    • (2011) Curr Biol , vol.21
    • Festa, R.A.1    Thiele, D.J.2
  • 20
    • 2342444345 scopus 로고    scopus 로고
    • Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter
    • Guo Y, Smith K, Lee J, Thiele DJ, Petris MJ. Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter. J Biol Chem 2004;279:17428-33.
    • (2004) J Biol Chem , vol.279 , pp. 17428-17433
    • Guo, Y.1    Smith, K.2    Lee, J.3    Thiele, D.J.4    Petris, M.J.5
  • 21
    • 70350374212 scopus 로고    scopus 로고
    • Copper-dependent recycling of hCTR1, the human high affinity copper transporter
    • Molloy SA, Kaplan JH. Copper-dependent recycling of hCTR1, the human high affinity copper transporter. J Biol Chem 2009;284:29704-13.
    • (2009) J Biol Chem , vol.284 , pp. 29704-29713
    • Molloy, S.A.1    Kaplan, J.H.2
  • 22
    • 33845317647 scopus 로고    scopus 로고
    • The internalization and degradation of human copper transporter 1 following cisplatin exposure
    • Holzer AK, Howell SB. The internalization and degradation of human copper transporter 1 following cisplatin exposure. Cancer Res 2006;66:10944-52.
    • (2006) Cancer Res , vol.66 , pp. 10944-10952
    • Holzer, A.K.1    Howell, S.B.2
  • 23
    • 8744280624 scopus 로고    scopus 로고
    • Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: Requirement for the extracellular methionine-rich clusters
    • Guo Y, Smith K, Petris MJ. Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters. J Biol Chem 2004;279:46393-9.
    • (2004) J Biol Chem , vol.279 , pp. 46393-46399
    • Guo, Y.1    Smith, K.2    Petris, M.J.3
  • 24
    • 77957771488 scopus 로고    scopus 로고
    • Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stability
    • Nose Y, Wood LK, KimBE, Prohaska JR, Fry RS, Spears JW, et al. Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stability. J Biol Chem 2010;285:32385-92.
    • (2010) J Biol Chem , vol.285 , pp. 32385-32392
    • Nose, Y.1    Wood, L.K.2    Kim, B.E.3    Prohaska, J.R.4    Fry, R.S.5    Spears, J.W.6
  • 25
    • 58549089871 scopus 로고    scopus 로고
    • Elevated copper and oxidative stress in cancer cells as a target for cancer treatment
    • Gupte A, Mumper RJ. Elevated copper and oxidative stress in cancer cells as a target for cancer treatment. Cancer Treat Rev 2009;35:32-46.
    • (2009) Cancer Treat Rev , vol.35 , pp. 32-46
    • Gupte, A.1    Mumper, R.J.2
  • 26
    • 67649371133 scopus 로고    scopus 로고
    • The use of copper-lowering therapy with tetrathiomolybdate in medicine
    • Brewer GJ. The use of copper-lowering therapy with tetrathiomolybdate in medicine. Expert Opin Investig Drugs 2009;18:89-97.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 89-97
    • Brewer, G.J.1
  • 27
    • 79953752779 scopus 로고    scopus 로고
    • Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7B
    • Dmitriev OY. Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7B. Biochem Cell Biol 2011;89:138-47.
    • (2011) Biochem Cell Biol , vol.89 , pp. 138-147
    • Dmitriev, O.Y.1
  • 28
    • 78650972288 scopus 로고    scopus 로고
    • Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo
    • Blair BG, Larson CA, Adams PL, Abada PB, Pesce CE, Safaei R, et al. Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo. Mol Pharmacol 2011;79:157-66.
    • (2011) Mol Pharmacol , vol.79 , pp. 157-166
    • Blair, B.G.1    Larson, C.A.2    Adams, P.L.3    Abada, P.B.4    Pesce, C.E.5    Safaei, R.6
  • 29
    • 0034702881 scopus 로고    scopus 로고
    • Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant
    • Lee J, Prohaska JR, Dagenais SL, Glover TW, Thiele DJ. Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant. Gene 2000;254:87-96.
    • (2000) Gene , vol.254 , pp. 87-96
    • Lee, J.1    Prohaska, J.R.2    Dagenais, S.L.3    Glover, T.W.4    Thiele, D.J.5
  • 30
    • 31544454133 scopus 로고    scopus 로고
    • Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status
    • Kuo YM, Gybina AA, Pyatskowit JW, Gitschier J, Prohaska JR. Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status. J Nutr 2006;136:21-6.
    • (2006) J Nutr , vol.136 , pp. 21-26
    • Kuo, Y.M.1    Gybina, A.A.2    Pyatskowit, J.W.3    Gitschier, J.4    Prohaska, J.R.5
  • 31
    • 70349479538 scopus 로고    scopus 로고
    • Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
    • Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, et al. Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci U S A 2009;106:16281-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16281-16286
    • Bertolini, G.1    Roz, L.2    Perego, P.3    Tortoreto, M.4    Fontanella, E.5    Gatti, L.6


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