Bioactive compounds extracted from ecklonia cava by using enzymatic hydrolysis protects high glucose-induced damage in INS-1 pancreatic β-cells

Applied Biochemistry and Biotechnology

Volumn 167, Issue 7, 2012, Pages 1973-1985

  Lee, Seung Hong ^a   Park, Mi Hwa ^b   Park, Sun Joo ^c   Kim, Jaeil ^c   Kim, Yong Tae ^d   Oh, Myung Cheol ^e   Jeong, Yoonhwa ^f   Kim, Misook ^a,f   Han, Ji Sook ^b   Jeon, You Jin ^a  

^a Jeju National University   (South Korea)

^b Pusan National University   (South Korea)

^c Pukyong National University   (South Korea)

^d Kunsan National University   (South Korea)

^e Jeju International University   (South Korea)

^f Dankook University   (South Korea)

Author keywords

Ecklonia cava; Enzymatic hydrolysate; High glucose; Oxidative stress; Pancreatic cells; Protective effects

Indexed keywords

ANTI-APOPTOTIC PROTEIN; ANTIOXIDANT ENZYME; BIOACTIVE COMPOUNDS; BROWN ALGAE; CELL VIABILITY; DOSE-DEPENDENT MANNER; ECKLONIA CAVA; ENZYMATIC HYDROLYSATE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; NUTRACEUTICALS; PROTECTIVE EFFECTS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASES;

CELL DEATH; ENZYMATIC HYDROLYSIS; LIPIDS; NITRIC OXIDE; OXIDATIVE STRESS; OXYGEN;

GLUCOSE;

ALGAL EXTRACT; CARBOHYDRASE; CATALASE; CELLULASE; ECKLONIA CAVA EXTRACT; GLUCOSE; GLUTATHIONE PEROXIDASE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN HYDROLYSATE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BROWN ALGA; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROLYSIS; HYPERGLYCEMIA; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; ENZYME ASSAYS; GLUCOSE; GLYCOSIDE HYDROLASES; HYDROLYSIS; INSULIN-SECRETING CELLS; INTRACELLULAR SPACE; LIPID PEROXIDATION; NITRIC OXIDE; PHAEOPHYTA; POLYPHENOLS; POLYSACCHARIDES; PROTECTIVE AGENTS; RATS; REACTIVE OXYGEN SPECIES; STAINING AND LABELING; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ECKLONIA CAVA; PHAEOPHYCEAE;

EID: 84866424748     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-012-9695-7     Document Type: Article

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