New reservoirs of HLA alleles: Pools of rare variants enhance immune defense

Trends in Genetics

Volumn 28, Issue 10, 2012, Pages 480-486

  Klitz, William ^a   Hedrick, Philip ^b   Louis, Edward J ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Gene conversion; HLA; MHC; Polymorphism; Population growth

Indexed keywords

ALLELE; DISEASE CARRIER; DNA POLYMORPHISM; DYNAMICS; GENE CONVERSION; GENE LOCUS; GENE MUTATION; GENETIC VARIABILITY; HAPLOTYPE; HLA SYSTEM; HUMAN; IMMUNITY; NONHUMAN; PATHOGEN LOAD; POPULATION RESEARCH; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMATOGENESIS;

ALLELES; HLA ANTIGENS; HUMANS; MUTATION; SELECTION, GENETIC;

EID: 84866414827     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2012.06.007     Document Type: Review

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